RIR2_CAEEL - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RIR2_CAEEL
• UniProt AC: P42170
• Protein Name: Ribonucleoside-diphosphate reductase small chain
• Gene Name: rnr-2
• Organism: Caenorhabditis elegans.
• Sequence Length: 381
• Protein Description: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides..
• Protein Sequence: MTLTEIQNVEKENAGASVPKHSSNKLKLEKELEKLEIVDQTKAASAEETNNESEVNELDADEPMLQDLDNRFVIFPLKHHDIWNFYKKAVASFWTVEEVDLGKDMNDWEKMNGDEQYFISRILAFFAASDGIVNENLCERFSNEVQVSEARFFYGFQIAIENIHSEMYSKLIETYIRDETERNTLFNAVDEFEFIKKKADWALRWISDKKASFAERLIAFAAVEGIFFSGSFASIFWLKKRGLMPGLTHSNELISRDEGLHRDFACLLYSKLQKKLTQQRIYDIIKDAVAIEQEFLTEALPVDMIGMNCRLMSQYIEFVADHLLVELGCDKLYKSKNPFDFMENISIDGKTNFFEKRVSEYQRPGVMVNEAERQFDLEADF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
45	Phosphorylation	VDQTKAASAEETNNE HCHHHHCCHHHHCCH	40.86	30078680
49	Phosphorylation	KAASAEETNNESEVN HHCCHHHHCCHHHHH	34.54	30078680
53	Phosphorylation	AEETNNESEVNELDA HHHHCCHHHHHCCCC	49.30	30078680

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RIR2_CAEEL !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RIR2_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RIR2_CAEEL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RIR2_CAEEL	rnr-2	physical	14704431

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.