dbPTM

RH7_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RH7_ARATH
UniProt AC	Q39189
Protein Name	DEAD-box ATP-dependent RNA helicase 7
Gene Name	RH7
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	671
Subcellular Localization	Nucleus.
Protein Description
Protein Sequence	MPSLMLSDKKEEKKMKKKMALDTPELDSKKGKKEQKLKLSDSDEEESEKKKSKKKDKKRKASEEEDEVKSDSSSEKKKSSKKVKLGVEDVEVDNPNAVSKFRISAPLREKLKANGIEALFPIQASTFDMVLDGADLVGRARTGQGKTLAFVLPILESLVNGPAKSKRKMGYGRSPSVLVLLPTRELAKQVAADFDAYGGSLGLSSCCLYGGDSYPVQEGKLKRGVDIVVGTPGRIKDHIERQNLDFSYLQFRVLDEADEMLRMGFVEDVELILGKVEDSTKVQTLLFSATLPSWVKNISNRFLKRDQKTIDLVGNDKMKASNSVRHIAIPCNKAAMARLIPDIISCYSSGGQTIIFAETKVQVSELSGLLDGSRALHGEIPQSQREVTLAGFRNGKFATLVATNVAARGLDINDVQLIIQCEPPREVEAYIHRSGRTGRAGNTGVAVTLYDSRKSSVSRIEKEAGIKFEHLAAPQPDEIARSGGMEAAEKVKQVCDSVVPAFLEAAKELLETSGLSAEVLLAKALAKTAGFTEIKKRSLLTSMENYVTLHLEAGKPIYSPSFVYGLLRRVLPDDKVEMIEGLSLTADKTGAVFDVKQSDLDLFIAGAQKSAGSMSLEVVKVMPKLQEREPLPQKRFGGGGRGNRFGGGGGNRFGGGGGRGRGGSGGRGQRY

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
40	Phosphorylation	KEQKLKLSDSDEEES HHHCCCCCCCCHHHH	33.22	19880383
42	Phosphorylation	QKLKLSDSDEEESEK HCCCCCCCCHHHHHH	43.47	30291188
47	Phosphorylation	SDSDEEESEKKKSKK CCCCHHHHHHHHHHH	58.98	23776212
62	Phosphorylation	KDKKRKASEEEDEVK HHHHHHHHHHHHHHH	48.88	23776212
70	Phosphorylation	EEEDEVKSDSSSEKK HHHHHHHCCCCCCCH	48.15	23776212
72	Phosphorylation	EDEVKSDSSSEKKKS HHHHHCCCCCCCHHH	42.74	23776212
73	Phosphorylation	DEVKSDSSSEKKKSS HHHHCCCCCCCHHHC	47.72	23776212
74	Phosphorylation	EVKSDSSSEKKKSSK HHHCCCCCCCHHHCC	58.34	23776212
443	Phosphorylation	RTGRAGNTGVAVTLY CCCCCCCCEEEEEEE	31.92	23776212
448	Phosphorylation	GNTGVAVTLYDSRKS CCCEEEEEEEECCCH	15.17	23776212
450	Phosphorylation	TGVAVTLYDSRKSSV CEEEEEEEECCCHHH	11.51	23776212
452	Phosphorylation	VAVTLYDSRKSSVSR EEEEEEECCCHHHHH	28.22	23776212
455	Phosphorylation	TLYDSRKSSVSRIEK EEEECCCHHHHHHHH	34.56	23776212
456	Phosphorylation	LYDSRKSSVSRIEKE EEECCCHHHHHHHHH	27.44	23776212
458	Phosphorylation	DSRKSSVSRIEKEAG ECCCHHHHHHHHHHC	29.50	23776212

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RH7_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RH7_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RH7_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
SUMO3_ARATH	SUMO3	physical	20855607

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RH7_ARATH

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks."; Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.; Plant Physiol. 150:889-903(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-40 AND SER-42, AND MASSSPECTROMETRY.	19376835 [Abstract]