RH38_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RH38_ARATH
• UniProt AC: Q93ZG7
• Protein Name: DEAD-box ATP-dependent RNA helicase 38
• Gene Name: RH38
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 496
• Subcellular Localization: Cytoplasm . Nucleus .
• Protein Description: ATP-dependent RNA helicase essential for mRNA export from the nucleus. Plays an important role in the positive regulation of CBF/DREB transcription factors..
• Protein Sequence: MADTVEKVPTVVESSSSSTVEASNSAEKTEPTTEKKKWGDVEDDDDEEEAVSELNSLSIKEEEKPDSILEEPEDSNIKAVTSGDTPYTSASRFEDLNLSPELMKGLYVEMKFEKPSKIQAISLPMIMTPPHKHLIAQAHNGSGKTTCFVLGMLSRVDPTLREPQALCICPTRELANQNMEVLQKMGKFTGITAELAVPDSTRGAPAATRGAPVSAHVVIGTPGTLKKWMAFKRLGLNHLKILVFDEADHMLATDGFRDDSLKIMKDIGRVNPNFQVLLFSATFNETVKDFVARTVKDPNQLFVKREDLALDSVKQYKVVCPKEQNKIEVIKDQIMELGDIGQTIIFVKTKASAQKVHKALAEMGYDVTSVHGNLTESDRDKIVKEFKECLTQVLIATDVIARGFDQQRVNLVVNYNLPTKYETGEPDYEVYLHRVGRAGRFGRKGAVFNLLLDDGWDKEVMEKIEKYFEANVKEIKSWNSEEEYKSALKEAGLLDE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MADTVEKVP ------CCCCCCCCC	22.60	22223895
14	Phosphorylation	KVPTVVESSSSSTVE CCCEEEECCCCCCEE	24.74	23776212
15	Phosphorylation	VPTVVESSSSSTVEA CCEEEECCCCCCEEC	22.27	23776212
16	Phosphorylation	PTVVESSSSSTVEAS CEEEECCCCCCEECC	37.27	23776212
17	Phosphorylation	TVVESSSSSTVEASN EEEECCCCCCEECCC	31.79	23776212
18	Phosphorylation	VVESSSSSTVEASNS EEECCCCCCEECCCC	38.12	23776212
19	Phosphorylation	VESSSSSTVEASNSA EECCCCCCEECCCCC	25.06	23776212
23	Phosphorylation	SSSTVEASNSAEKTE CCCCEECCCCCCCCC	20.15	23776212
25	Phosphorylation	STVEASNSAEKTEPT CCEECCCCCCCCCCC	35.00	23776212
29	Phosphorylation	ASNSAEKTEPTTEKK CCCCCCCCCCCCCCC	38.41	23776212
67	Phosphorylation	KEEEKPDSILEEPED CCCCCCCCCCCCCCC	37.29	19880383
179	Sulfoxidation	RELANQNMEVLQKMG HHHHHHCHHHHHHHC	2.44	23289948
200	Phosphorylation	AELAVPDSTRGAPAA EEEECCCCCCCCCCC	17.59	19880383
221	Phosphorylation	SAHVVIGTPGTLKKW EEEEEECCCCHHHHH	13.86	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RH38_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RH38_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RH38_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NP214_ARATH	emb1011	physical	22898497
GLE1_ARATH	emb1745	physical	25670768
IPPK_ARATH	IPK1	physical	25670768

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.