NP214_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NP214_ARATH
• UniProt AC: F4I1T7
• Protein Name: Nuclear pore complex protein NUP214 {ECO:0000303|PubMed:21189294}
• Gene Name: NUP214 {ECO:0000303|PubMed:21189294}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 1819
• Subcellular Localization: Nucleus envelope . Nucleus, nuclear pore complex .
• Protein Description: Required for normal embryogenesis and seed viability. Involved in the first asymmetrical cell division of the zygote. Regulates the number and planes of cell divisions required for generating the normal embryo proper and suspensor, apical-basal axis, cotyledons and meristem..
• Protein Sequence: MSRVEIEEDTEGDRISTNDYYFERIGEPISIKEDDAQYDLENPPSQPLAISERHAVLFVAHSSGFFVGRTNDVISASKNSNGNGDKVFIQDLSLVDVPVGDVRILSLSADDSILAVTVAADIHFFSVDSLLKKDAKPSFSYSPDESGFVKDFRWRRNDKHSYLVLSNTGKLFHGIDNAPPRHVMDAVDAVEWSSKGSYIAVAQDNSLRIFSSKFNEKRCIALSFDSWIGDSDEDCFVKVDSIRWVRNNCILLGCFQLIEGREENYLVQVIRSPDGKISDGSTNLVALSFSDLFPCSMDDLVPVGVGPHLLFSYIDQCKLAVTANRKSIDEHIVLLDWSSGDDKSAVSVVDIDRETFLPRIGLQENNDDNTVMGLCIDRVSIEGTVNVRSGDDELKELQPYFVLVCLTLEGKLVMFNVASVAGRPASSDTDLASSSDIEDAYTPLIEDDLSKQSSEKHQQLNIAVQNDQKHLNTEKFSTEQRLPNENIFSKEFESVKSSVSGDNNKKQEPYAEKPLQVEDAQQSMIPRLSGTSFGQLPMSLGYDTNKFAGFGPALPVSEKLQKDIFAQSNSMHLQANVESKSTAAFFGSPGLQNAILQSPQNTSSQPWSSGKSVSPPDFVSGPFPSMRDTQHKQSVQSGTGYVNPPMSIKDKSVQVIETGRVSALSNLSPLLGQNQDTNEGVEKIEPIPSIRASQLSQQVKSSFEKSASHQQHKTPLSTGPLRLEHNMSNQPSNINEMAREMDTLLQSIEGPGGFKDSCAFILKSNVEELEQGLESLAGKCQTWKSTIHEQQAEIQHLLDKTIQVLAKKTYMEGMYKQTADNQYWQLWNRQKLNPELEAKRQHIMKLNKDLTHQLIELERYFNRLELDRYNEDGGHPVARRGVPNRSAPSRRVQSLHSLHNTMSSQLAAAEQLSECLSKQMTYLKIDSPVKKNVKQELFETIGIPYDASFSSPDAVKAKNASSAKNLLLSSIPASINQQSRQRQSSAMKNSDPETARRRRESLDRVIFNWAAFEPPKTTVKRMLLQEQQKTGMNQQTVLSERLRSANNTQDRSLLHVKDHASPVVSSNKGIMESFQQDTSEAQSTPFKTRPPMPQSNSPFTISPISASKPSFNWSGNKSSNTTSYAEESAPSQIKDTRTVSQPGGSSFLPKRPVASTVLEQTEKKAGEFKFSEAKANAFVETAAGSVQRLSTTSSGSDFESSKGFGAQFSTMSSGAPASSFSSKSLFGFNSSSSIPGDKFTFPAVTAPLSGTPLDSTSTLFTASSAPVSSSSQDPVPASIPISSAPVPQTFSVTSTSTVSATGFNVPFGKPLTSVKVDLNQAAPSTPSPSPGPTAGFTFNLPALSPSSPEMVSSSTGQSSLFPPSAPTSQVSSDQASATSSLTDSSRLFSSTSLSSTPPITPPDAFQSPQVSTPSSAVPITEPVSEPKKPEAQSSSILSTQSTVDSVANATKTQNEPLPVKSEISNPGTTVTPVSSSGFLSGFSSGTQSSLASMAAPSFSWPGSSQPQQLSSTPAPFPASSPTSASPFGEKKDIVDTQEDEMDEEAPEASQTTELSMGSFGGFGLGSTPNPGAPKTNPFGGPFGNATTTTSNPFNMTVPSGELFKPASFNFQNPQPSQPAGFGSFSVTPSQTPAQSGFGQPSQIGGGQQALGSVLGSFGQSRQIGAGLPGATFGSPTGFGGSNPGSGLPNAPASGGFAAAGSSATGGFAAMASAGRGFAGASSTPTGGFAALASGSGGFAGAAPGGGGGGFGGLGSGTGGFGGFAPQGSSGGFAGAAGGGGFGGFGGQAQGQAGGGGFSAFGGNSGATGKPSELFTQMRK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
193	Phosphorylation	AVDAVEWSSKGSYIA HHHEEECCCCCCEEE		24894044
194	Phosphorylation	VDAVEWSSKGSYIAV HHEEECCCCCCEEEE		24894044
419	Phosphorylation	LVMFNVASVAGRPAS EEEEEEHHHCCCCCC		19880383
426	Phosphorylation	SVAGRPASSDTDLAS HHCCCCCCCCCCCCC		19880383
427	Phosphorylation	VAGRPASSDTDLASS HCCCCCCCCCCCCCC		26187819
429	Phosphorylation	GRPASSDTDLASSSD CCCCCCCCCCCCCCC		27531888
433	Phosphorylation	SSDTDLASSSDIEDA CCCCCCCCCCCHHHH		26187819
434	Phosphorylation	SDTDLASSSDIEDAY CCCCCCCCCCHHHHH		19880383
441	Phosphorylation	SSDIEDAYTPLIEDD CCCHHHHHHHHHHCC		19880383
708	Phosphorylation	SSFEKSASHQQHKTP HHHHHHHHCCCCCCC		24894044
714	Phosphorylation	ASHQQHKTPLSTGPL HHCCCCCCCCCCCCC		24894044
927	Phosphorylation	MTYLKIDSPVKKNVK CCEEECCCCCCHHHH		23776212
1095	Phosphorylation	TRPPMPQSNSPFTIS CCCCCCCCCCCCEEC		28295753
1097	Phosphorylation	PPMPQSNSPFTISPI CCCCCCCCCCEECCC		28295753
1100	Phosphorylation	PQSNSPFTISPISAS CCCCCCCEECCCCCC		28295753
1102	Phosphorylation	SNSPFTISPISASKP CCCCCEECCCCCCCC		28295753
1105	Phosphorylation	PFTISPISASKPSFN CCEECCCCCCCCCCC		28295753
1107	Phosphorylation	TISPISASKPSFNWS EECCCCCCCCCCCCC		28295753

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NP214_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NP214_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NP214_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of NP214_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.