RGDSR_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RGDSR_HUMAN
• UniProt AC: Q8IZJ4
• Protein Name: Ral-GDS-related protein
• Gene Name: RGL4
• Organism: Homo sapiens (Human).
• Sequence Length: 473
• Subcellular Localization: Cytoplasmic vesicle.
• Protein Sequence: MRKLLTNLPAAAVLSAQVYSAVLQGLWEENVCGTPGRTRVCTALLYGQVCPFQDSTDGLRTITSILFNWPPENTSVYYQPPQRSSFRIKLAFRNLSWPGLGLEDHQEIVLGQLVLPEPNEAKPDDPAPRPGQHALTMPALEPAPPLLADLGPALEPESPAALGPPGYLHSAPGPAPAPGEGPPPGTVLEPQSAPESSCPCRGSVKNQPSEELPDMTTFPPRLLAEQLTLMDAELFKKVVLHECLGCIWGQGHLKGNEHMAPTVRATIAHFNRLTNCITTSCLGDHSMRARDRARVVEHWIKVARECLSLNNFSSVHVIVSALCSNPIGQLHKTWAGVSSKSMKELKELCKKDTAVKRDLLIKAGSFKVATQERNPQRVQMRLRRQKKGVVPFLGDFLTELQRLDSAIPDDLDGNTNKRSKEVRVLQEMQLLQVAAMNYRLRPLEKFVTYFTRMEQLSDKESYKLSCQLEPENP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
85	Phosphorylation	YQPPQRSSFRIKLAF ECCCCCCCEEEEEEE	22.27	17081983
228	Phosphorylation	RLLAEQLTLMDAELF HHHHHHHHHCCHHHH	21.52	-
333	Phosphorylation	PIGQLHKTWAGVSSK CCHHHHHHHCCCCCH	15.14	26074081
338	Phosphorylation	HKTWAGVSSKSMKEL HHHHCCCCCHHHHHH	31.00	26074081
339	Phosphorylation	KTWAGVSSKSMKELK HHHCCCCCHHHHHHH	26.75	26074081
340	Acetylation	TWAGVSSKSMKELKE HHCCCCCHHHHHHHH	47.25	20167786
341	Phosphorylation	WAGVSSKSMKELKEL HCCCCCHHHHHHHHH	36.71	26074081
343	Acetylation	GVSSKSMKELKELCK CCCCHHHHHHHHHHH	67.97	20167786
417	Ubiquitination	DLDGNTNKRSKEVRV CCCCCCCHHHHHHHH	56.88	-
419	Phosphorylation	DGNTNKRSKEVRVLQ CCCCCHHHHHHHHHH	34.47	-
465	Phosphorylation	DKESYKLSCQLEPEN CHHHCCCCEECCCCC	8.82	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RGDSR_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RGDSR_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RGDSR_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RASH_HUMAN	HRAS	physical	12874025
RALA_HUMAN	RALA	physical	12874025
RALB_HUMAN	RALB	physical	12874025
RAP1A_HUMAN	RAP1A	physical	12874025
OCAD1_HUMAN	OCIAD1	physical	26186194
DCX_HUMAN	DCX	physical	28514442
OCAD1_HUMAN	OCIAD1	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.