dbPTM

RFX4_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RFX4_MOUSE
UniProt AC	Q7TNK1
Protein Name	Transcription factor RFX4
Gene Name	Rfx4
Organism	Mus musculus (Mouse).
Sequence Length	735
Subcellular Localization	Nucleus .
Protein Description	Isoform 1: Transcription factor that plays a role in early brain development. May activate transcription by interacting directly with the X-box. May activate transcription from CX3CL1 promoter through the X-box during brain development..
Protein Sequence	MHCGLLEEPDMDSTESWIERCLNESENKRYSSHTSLGNVSNDENEEKENNRASKPHSTPATLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQFPQLTTRRLGTRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKREVTKQTVAYSPRSKLGTLLPDFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRILDTVIRANFDEVQSFLLHFWQGMPPHMLPVLGSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLSSITKQTLYTMEDSRDEHRRLIIQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANELMRAMKGEGSTAEAQEEIILTEATPPTPSPGPSFSPAKSATSVEVPPPSSPVSNPSPEYTGLSTAGAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRSTHMPSSSVTHRIPVYSHREEHGYTGSYNYGSYGNQHPHPLQNQYPALPHDTAISGPLHYSPYHRSSAQYPFNSPTSRMEPCLMSSTPRLHPTPVTPRWPEVPTANACYTSPSVHSTRYGNSSDMYTPLTTRRNSEYEHMQHFPGFAYINGEASTGWAK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
40	Phosphorylation	HTSLGNVSNDENEEK CCCCCCCCCCCCHHH	42.43	29899451
669	Phosphorylation	STPRLHPTPVTPRWP CCCCCCCCCCCCCCC	21.46	24759943
706	Phosphorylation	SDMYTPLTTRRNSEY CCCCCCCCCCCCCCC	21.33	28576409

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RFX4_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RFX4_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RFX4_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
SSBP3_MOUSE	Ssbp3	physical	20211142

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RFX4_MOUSE

Related Literatures of Post-Translational Modification