dbPTM

RBPJL_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RBPJL_HUMAN
UniProt AC	Q9UBG7
Protein Name	Recombining binding protein suppressor of hairless-like protein
Gene Name	RBPJL
Organism	Homo sapiens (Human).
Sequence Length	517
Subcellular Localization	Nucleus .
Protein Description	Putative transcription factor, which cooperates with EBNA2 to activate transcription..
Protein Sequence	MDPAGAADPSVPPNPLTHLSLQDRSEMQLQSEADRRSLPGTWTRSSPEHTTILRGGVRRCLQQQCEQTVRILHAKVAQKSYGNEKRFFCPPPCVYLSGPGWRVKPGQDQAHQAGETGPTVCGYMGLDSASGSATETQKLNFEQQPDSREFGCAKTLYISDADKRKHFRLVLRLVLRGGRELGTFHSRLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEDGAFVASARQWAAFTLHLADGHSAQGDFPPREGYVRYGSLVQLVCTVTGITLPPMIIRKVAKQCALLDVDEPISQLHKCAFQFPGSPPGGGGTYLCLATEKVVQFQASPCPKEANRALLNDSSCWTIIGTESVEFSFSTSLACTLEPVTPVPLISTLELSGGGDVATLELHGENFHAGLKVWFGDVEAETMYRSPRSLVCVVPDVAAFCSDWRWLRAPITIPMSLVRADGLFYPSAFSFTYTPEYSVRPGHPGVPEPATDADALLESIHQEFTRTNFHLFIQT

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
41	Phosphorylation	DRRSLPGTWTRSSPE HHCCCCCCCCCCCCC	23.02	23403867
43	Phosphorylation	RSLPGTWTRSSPEHT CCCCCCCCCCCCCCH	22.10	23403867
79	Ubiquitination	LHAKVAQKSYGNEKR HHHHHHHHHHCCCCC	35.59	-
223	Phosphorylation	SLFNRLRSQTVSTRY HHHHHHHCCCCCCEE	34.49	23403867
225	Phosphorylation	FNRLRSQTVSTRYLS HHHHHCCCCCCEEEE	20.05	23403867
227	Phosphorylation	RLRSQTVSTRYLSVE HHHCCCCCCEEEEEC	15.56	23403867
228	Phosphorylation	LRSQTVSTRYLSVED HHCCCCCCEEEEECC	20.99	23403867
424 (in isoform 2)	Phosphorylation	-	26.93	27732954
426 (in isoform 2)	Phosphorylation	-	18.50	27732954
427 (in isoform 2)	Phosphorylation	-	29.39	27732954
454	Phosphorylation	RWLRAPITIPMSLVR HHHCCCCCCCHHHEE	20.26	23403867
458	Phosphorylation	APITIPMSLVRADGL CCCCCCHHHEECCCC	20.54	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RBPJL_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RBPJL_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RBPJL_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
A4_HUMAN	APP	physical	21832049

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RBPJL_HUMAN

Related Literatures of Post-Translational Modification