RBOHF_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RBOHF_ARATH
• UniProt AC: O48538
• Protein Name: Respiratory burst oxidase homolog protein F
• Gene Name: RBOHF
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 944
• Subcellular Localization: Cell membrane ; Multi-pass membrane protein .
• Protein Description: Calcium-dependent NADPH oxidase that generates superoxide. Generates reactive oxygen species (ROS) during incompatible interactions with pathogens and is important in the regulation of the hypersensitive response (HR). Involved in abscisic acid-induced stomatal closing and in UV-B and abscisic acid ROS-dependent signaling..
• Protein Sequence: MKPFSKNDRRRWSFDSVSAGKTAVGSASTSPGTEYSINGDQEFVEVTIDLQDDDTIVLRSVEPATAINVIGDISDDNTGIMTPVSISRSPTMKRTSSNRFRQFSQELKAEAVAKAKQLSQELKRFSWSRSFSGNLTTTSTAANQSGGAGGGLVNSALEARALRKQRAQLDRTRSSAQRALRGLRFISNKQKNVDGWNDVQSNFEKFEKNGYIYRSDFAQCIGMKDSKEFALELFDALSRRRRLKVEKINHDELYEYWSQINDESFDSRLQIFFDIVDKNEDGRITEEEVKEIIMLSASANKLSRLKEQAEEYAALIMEELDPERLGYIELWQLETLLLQKDTYLNYSQALSYTSQALSQNLQGLRGKSRIHRMSSDFVYIMQENWKRIWVLSLWIMIMIGLFLWKFFQYKQKDAFHVMGYCLLTAKGAAETLKFNMALILFPVCRNTITWLRSTRLSYFVPFDDNINFHKTIAGAIVVAVILHIGDHLACDFPRIVRATEYDYNRYLFHYFQTKQPTYFDLVKGPEGITGILMVILMIISFTLATRWFRRNLVKLPKPFDRLTGFNAFWYSHHLFVIVYILLILHGIFLYFAKPWYVRTTWMYLAVPVLLYGGERTLRYFRSGSYSVRLLKVAIYPGNVLTLQMSKPTQFRYKSGQYMFVQCPAVSPFEWHPFSITSAPEDDYISIHIRQLGDWTQELKRVFSEVCEPPVGGKSGLLRADETTKKSLPKLLIDGPYGAPAQDYRKYDVLLLVGLGIGATPFISILKDLLNNIVKMEEHADSISDFSRSSEYSTGSNGDTPRRKRILKTTNAYFYWVTREQGSFDWFKGVMNEVAELDQRGVIEMHNYLTSVYEEGDARSALITMVQALNHAKNGVDIVSGTRVRTHFARPNWKKVLTKLSSKHCNARIGVFYCGVPVLGKELSKLCNTFNQKGSTKFEFHKEHF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
13	Phosphorylation	KNDRRRWSFDSVSAG CCCCCCCCCCCCCCC	19.84	30291188
130	Phosphorylation	KRFSWSRSFSGNLTT HHHHCCCCCCCCEEE	20.46	30407730
132	Phosphorylation	FSWSRSFSGNLTTTS HHCCCCCCCCEEECC	28.19	30407730
136	Phosphorylation	RSFSGNLTTTSTAAN CCCCCCEEECCCCCC	31.84	30407730
137	Phosphorylation	SFSGNLTTTSTAANQ CCCCCEEECCCCCCC	23.16	30407730
138	Phosphorylation	FSGNLTTTSTAANQS CCCCEEECCCCCCCC	20.88	30407730
139	Phosphorylation	SGNLTTTSTAANQSG CCCEEECCCCCCCCC	17.60	30407730
140	Phosphorylation	GNLTTTSTAANQSGG CCEEECCCCCCCCCC	27.91	30407730
145	Phosphorylation	TSTAANQSGGAGGGL CCCCCCCCCCCCCHH	38.71	30407730
354	Phosphorylation	SQALSYTSQALSQNL HHHHHHHHHHHHHHH	12.77	-
358	Phosphorylation	SYTSQALSQNLQGLR HHHHHHHHHHHCHHH	21.75	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RBOHF_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RBOHF_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RBOHF_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CIPKQ_ARATH	AT5G21326	physical	23162070

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.