| UniProt ID | RAB6C_HUMAN | |
|---|---|---|
| UniProt AC | Q9H0N0 | |
| Protein Name | Ras-related protein Rab-6C | |
| Gene Name | RAB6C | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 254 | |
| Subcellular Localization | Nucleus . Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . | |
| Protein Description | May be involved in the regulation of centrosome duplication and cell cycle progression.. | |
| Protein Sequence | MSAGGDFGNPLRKFKLVFLGEQSVAKTSLITRFRYDSFDNTYQAIIGIDFLSKTMYLEDGTIGLRLWDTAGQERLRSLIPRYIRDSAAAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIITLVGNRTDLADKRQVSVEEGERKAKGLNVTFIETRAKAGYNVKQLFRRVAAALPGMESTQDGSREDMSDIKLEKPQEQTVSEGGCSCYSPMSSSTLPQKPPYSFIDCSVNIGLNLFPSLITFCNSSLLPVSWR | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Phosphorylation | ------MSAGGDFGN ------CCCCCCCCC | 35.30 | 28355574 | |
| 28 | Phosphorylation | EQSVAKTSLITRFRY CCCCCCEECCCEEEE | 19.64 | 24719451 | |
| 56 | Phosphorylation | DFLSKTMYLEDGTIG EECCCEEEECCCCEE | 16.51 | - | |
| 69 | Phosphorylation | IGLRLWDTAGQERLR EEEEEECCHHHHHHH | 22.55 | - | |
| 82 | O-AMP-tyrosine | LRSLIPRYIRDSAAA HHHHHHHHHHHCCCE | 8.58 | - | |
| 82 | AMPylation | LRSLIPRYIRDSAAA HHHHHHHHHHHCCCE | 8.58 | 21822290 | |
| 112 | Methylation | TKWIDDVRTERGSDV CHHHHHHHHHCCCCE | 37.55 | - | |
| 164 | Ubiquitination | AKAGYNVKQLFRRVA HHCCCCHHHHHHHHH | 37.33 | 21890473 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RAB6C_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RAB6C_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RAB6C_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| BICL2_MOUSE | Ccdc64b | physical | 20360680 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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