dbPTM

BICL2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	BICL2_MOUSE
UniProt AC	Q8CHW5
Protein Name	BICD family-like cargo adapter 2
Gene Name	Bicdl2
Organism	Mus musculus (Mouse).
Sequence Length	507
Subcellular Localization
Protein Description
Protein Sequence	MDSPGEPSFPSGLLSGGASPSGDEGFFPFVLERRDSFLGGGPGPEEPEDLALQLQQKEKDLLLAAELGKMLLERNEELRRQLETLNTQHLEHEERLQQENHELRRGLAARGAEWEARAVELEGDVEALRAQLGEQRSERQDSGRERARALGELSEQNLRLSQQLAQASRTEQELQRELDTLRERCQTQALAGAELGARLESLQAENQMLQDRRQDLEAQIRGLREEVDKGQNRLQTTHEELLLLRRERKEHKLELERARFEAGEALRTLRGLQRRVSELEEESRLQDTEISGASLQTELAHSLDSDQDQDQQVNECGGSQAILSPETQETSSPQPSIQEEILEPPKKRASLSPVEILEEKEAEVARLQDEITLHRTELQTLRDELQRQKELRAQDNPEEALSSALSDRDEAVNKAMKLSLELSRVSLERDSLSRELLRAIRQKVALTQELEAWQDDMQVVIGQQLRSQRQKELSEAAAAPRRAKTRFSLRLGSGQSGGFLSNLFRRT

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
36	Phosphorylation	FVLERRDSFLGGGPG HHHEECCCCCCCCCC	22817900
277	Phosphorylation	RGLQRRVSELEEESR HHHHHHHHHHHHHHH	19367708
350	Phosphorylation	EPPKKRASLSPVEIL CCCCCCCCCCCHHHH	26239621
488	Phosphorylation	RRAKTRFSLRLGSGQ HHCCCCEEEECCCCC	30372032
501	Phosphorylation	GQSGGFLSNLFRRT- CCCCCHHHHHHCCC-	28059163

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of BICL2_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of BICL2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of BICL2_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DC1I1_HUMAN	DYNC1I1	physical	20360680
DCTN1_HUMAN	DCTN1	physical	20360680
DYHC1_HUMAN	DYNC1H1	physical	20360680

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of BICL2_MOUSE

Related Literatures of Post-Translational Modification