| UniProt ID | RAB15_HUMAN | |
|---|---|---|
| UniProt AC | P59190 | |
| Protein Name | Ras-related protein Rab-15 | |
| Gene Name | RAB15 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 212 | |
| Subcellular Localization |
Cell membrane Lipid-anchor Cytoplasmic side . |
|
| Protein Description | May act in concert with RAB3A in regulating aspects of synaptic vesicle membrane flow within the nerve terminal.. | |
| Protein Sequence | MAKQYDVLFRLLLIGDSGVGKTCLLCRFTDNEFHSSHISTIGVDFKMKTIEVDGIKVRIQIWDTAGQERYQTITKQYYRRAQGIFLVYDISSERSYQHIMKWVSDVDEYAPEGVQKILIGNKADEEQKRQVGREQGQQLAKEYGMDFYETSACTNLNIKESFTRLTELVLQAHRKELEGLRMRASNELALAELEEEEGKPEGPANSSKTCWC | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 3 | Ubiquitination | -----MAKQYDVLFR -----CHHHHHHHHH | 48.36 | - | |
| 17 | Phosphorylation | RLLLIGDSGVGKTCL HHEHHCCCCCCCEEE | 30.11 | - | |
| 56 | Acetylation | TIEVDGIKVRIQIWD EEEECCEEEEEEEEC | 30.87 | 30591747 | |
| 64 | Phosphorylation | VRIQIWDTAGQERYQ EEEEEECCCCHHHHH | 20.07 | 21815630 | |
| 88 | Phosphorylation | AQGIFLVYDISSERS CCCEEEEEECCCHHH | 15.09 | 20068231 | |
| 92 | Phosphorylation | FLVYDISSERSYQHI EEEEECCCHHHHHHH | 37.05 | - | |
| 95 | Phosphorylation | YDISSERSYQHIMKW EECCCHHHHHHHHHH | 25.70 | 28152594 | |
| 96 | Phosphorylation | DISSERSYQHIMKWV ECCCHHHHHHHHHHH | 15.44 | 28152594 | |
| 116 | Ubiquitination | YAPEGVQKILIGNKA HCCCHHHHHEECCCC | 36.75 | - | |
| 158 (in isoform 2) | Phosphorylation | - | 6.20 | - | |
| 185 | Phosphorylation | EGLRMRASNELALAE HHHHHHHHCHHHHHH | 22.07 | 25849741 | |
| 210 | Geranylgeranylation | PANSSKTCWC----- CCCCCCCCCC----- | 3.92 | - | |
| 212 | Methylation | NSSKTCWC------- CCCCCCCC------- | 4.32 | - | |
| 212 | Geranylgeranylation | NSSKTCWC------- CCCCCCCC------- | 4.32 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RAB15_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RAB15_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RAB15_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| MSS4_HUMAN | RABIF | physical | 12105226 | |
| GDS1_HUMAN | RAP1GDS1 | physical | 28514442 | |
| TOIP2_HUMAN | TOR1AIP2 | physical | 28514442 | |
| IFG15_HUMAN | TOR1AIP2 | physical | 28514442 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
