QKI_MOUSE - dbPTM
QKI_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID QKI_MOUSE
UniProt AC Q9QYS9
Protein Name Protein quaking
Gene Name Qki
Organism Mus musculus (Mouse).
Sequence Length 341
Subcellular Localization Cytoplasm. Nucleus.
Isoform 1: Cytoplasm. Nucleus. Isoform 1 localizes predominantly in the nucleus and at lower levels in cytoplasm. It shuttles between the cytoplasm and the nucleus.
Isoform 3: Cytoplasm. Nucleus. Isoform 3 localizes predomi
Protein Description RNA-binding protein that plays a central role in myelinization. [PubMed: 10864952]
Protein Sequence MVGEMETKEKPKPTPDYLMQLMNDKKLMSSLPNFCGIFNHLERLLDEEISRVRKDMYNDTLNGSTEKRSAELPDAVGPIVQLQEKLYVPVKEYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKEEQNRGKPNWEHLNEDLHVLITVEDAQNRAEIKLKRAVEEVKKLLVPAAEGEDSLKKMQLMELAILNGTYRDANIKSPALAFSLAATAQAAPRIITGPAPVLPPAALRTPTPAGPTIMPLIRQIQTAVMPNGTPHPTAAIVPPGPEAGLIYTPYEYPYTLAPATSILEYPIEPSGVLGAVATKVRRHDMRVHPYQRIVTADRAATGN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
54UbiquitinationEEISRVRKDMYNDTL
HHHHHHHHHHHCCCC		43.9522790023
54 (in isoform 7)Ubiquitination-43.9522790023
69PhosphorylationNGSTEKRSAELPDAV
CCCCCCCCCCCCCCC		36.8424068923
87PhosphorylationVQLQEKLYVPVKEYP
HEEECCEECCHHHCC		17.4925367039
91UbiquitinationEKLYVPVKEYPDFNF
CCEECCHHHCCCCCC		45.5222790023
91 (in isoform 7)Ubiquitination-45.5222790023
188PhosphorylationPAAEGEDSLKKMQLM
CCCCCCCHHHHHHHH		37.4729176673
190UbiquitinationAEGEDSLKKMQLMEL
CCCCCHHHHHHHHHH		50.5922790023
190 (in isoform 7)Ubiquitination-50.5922790023
203PhosphorylationELAILNGTYRDANIK
HHHHHCCCCCCCCCC		17.82-
210 (in isoform 7)Ubiquitination-50.6322790023
210UbiquitinationTYRDANIKSPALAFS
CCCCCCCCCHHHHHH		50.6322790023
211 (in isoform 6)Phosphorylation-16.1724899341
211PhosphorylationYRDANIKSPALAFSL
CCCCCCCCHHHHHHH		16.1725266776
213 (in isoform 6)Phosphorylation-20.7227742792
217PhosphorylationKSPALAFSLAATAQA
CCHHHHHHHHHHHHH		16.1126643407
221PhosphorylationLAFSLAATAQAAPRI
HHHHHHHHHHHCCCE		17.4420047950
227MethylationATAQAAPRIITGPAP
HHHHHCCCEECCCCC		28.3724129315
242MethylationVLPPAALRTPTPAGP
CCCHHHHCCCCCCCC		33.6526542117
242Asymmetric dimethylarginineVLPPAALRTPTPAGP
CCCHHHHCCCCCCCC		33.65-
243PhosphorylationLPPAALRTPTPAGPT
CCHHHHCCCCCCCCC		32.1526643407
245PhosphorylationPAALRTPTPAGPTIM
HHHHCCCCCCCCCHH		25.7625521595
250PhosphorylationTPTPAGPTIMPLIRQ
CCCCCCCCHHHHHHH		29.0526643407
256DimethylationPTIMPLIRQIQTAVM
CCHHHHHHHHHHHCC		34.92-
256MethylationPTIMPLIRQIQTAVM
CCHHHHHHHHHHHCC		34.9224129315
339PhosphorylationVTADRAATGN-----
EECCHHHCCC-----		35.95-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of QKI_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of QKI_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of QKI_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
QKI_MOUSEQkphysical
22751500
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of QKI_MOUSE

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Related Literatures of Post-Translational Modification

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