PTH_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PTH_HUMAN
• UniProt AC: Q86Y79
• Protein Name: Probable peptidyl-tRNA hydrolase
• Gene Name: PTRH1
• Organism: Homo sapiens (Human).
• Sequence Length: 214
• Protein Sequence: MRPGGFLGAGQRLSRAMSRCVLEPRPPGKRWMVAGLGNPGLPGTRHSVGMAVLGQLARRLGVAESWTRDRHCAADLALAPLGDAQLVLLRPRRLMNANGRSVARAAELFGLTAEEVYLVHDELDKPLGRLALKLGGSARGHNGVRSCISCLNSNAMPRLRVGIGRPAHPEAVQAHVLGCFSPAEQELLPLLLDRATDLILDHIRERSQGPSLGP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
133	Malonylation	PLGRLALKLGGSARG HHHHHHHHHCCCCCC	39.21	26320211
133	Acetylation	PLGRLALKLGGSARG HHHHHHHHHCCCCCC	39.21	25953088
196	Phosphorylation	PLLLDRATDLILDHI HHHHHHHHHHHHHHH	32.03	24825855
207	Phosphorylation	LDHIRERSQGPSLGP HHHHHHHHCCCCCCC	34.43	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PTH_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PTH_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PTH_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
FAM9B_HUMAN	FAM9B	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.