PRP3_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PRP3_SCHPO
• UniProt AC: Q09856
• Protein Name: U4/U5/U6 small nuclear ribonucleoprotein prp3
• Gene Name: prp3
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 542
• Subcellular Localization: Nucleus . Cytoplasm, cytoskeleton, spindle . Cytoplasm, cytoskeleton, spindle pole .
• Protein Description: Participates in pre-mRNA splicing and in nuclear mRNA export. May play a role in the assembly of the U4/U5/U6 tri-snRNP complex..
• Protein Sequence: MDRNKRRLESSQLRESSSPNSQNKPNAMEEIKRRRLQLEQRLAQQAQVPWEKRSENGNNAGMETIQNRISELKEKTAKRFNANIPKSEGLFRDDSNGAKGGLKVGIHPVLLDGNIQNTILTPENRKRTASFSTKGVSLSQHQLLKPPAITEQNPFLDTAPTPRLEDSPFYDPRTKESRKTRGSRNLHLNESGKFIEEANQARRQARLEDLKKRIALHSHKAGIEDELDITSKSIGRDTIPNIEWWDLPFIKDYNDYGDENNWLIDGPQSIINSAIQHPIPVLPPYAKNQPSSHSVFLTKKEQKKIRRQTRAEARKEKQDRQLLGIEPPEPPKVKLSNLMHVLGDDAIKDPTKIEAEVRKQVEERRLRHERENEERKLTPEERKEKAFRKKDEDSAAGLRCLVFRIKYLAHRPHRLKIDLNAKQWGATGVCILNANFNLVIFEAGQKAIKKLKRLMLERIDWTDTSRNSIIAQGNKLVDTEGRELNYTENTCNLVWEGEIGRRAFRYWSFRSCPSENDAKSYLEEQGGAEHFWMLAKSWSENV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
16	Phosphorylation	ESSQLRESSSPNSQN HHHHHHCCCCCCCCC		29996109
17	Phosphorylation	SSQLRESSSPNSQNK HHHHHCCCCCCCCCC		29996109
18	Phosphorylation	SQLRESSSPNSQNKP HHHHCCCCCCCCCCC		29996109
21	Phosphorylation	RESSSPNSQNKPNAM HCCCCCCCCCCCCHH		29996109
54	Phosphorylation	QVPWEKRSENGNNAG CCCHHHCCCCCCCHH		21712547
118	Phosphorylation	LDGNIQNTILTPENR ECCCEECCEECCCCC		29996109
121	Phosphorylation	NIQNTILTPENRKRT CEECCEECCCCCCCC		29996109
128	Phosphorylation	TPENRKRTASFSTKG CCCCCCCCCCCCCCC		21712547
130	Phosphorylation	ENRKRTASFSTKGVS CCCCCCCCCCCCCCC		27738172
132	Phosphorylation	RKRTASFSTKGVSLS CCCCCCCCCCCCCCC		24763107
191	Phosphorylation	RNLHLNESGKFIEEA CCEEECCHHHHHHHH		29996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PRP3_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PRP3_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PRP3_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
YJ03_SCHPO	rhn1	genetic	22681890
GBB_SCHPO	git5	genetic	22681890
CYB51_SCHPO	SPBC29A10.16c	genetic	22681890

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.