PPI1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PPI1_ARATH
• UniProt AC: O23144
• Protein Name: Proton pump-interactor 1
• Gene Name: PPI1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 612
• Subcellular Localization: Cell membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane ; Single-pass membrane protein .
• Protein Description: Promotes AHA1 plasma membrane ATPase activity by binding to a site different from the 14-3-3 binding site..
• Protein Sequence: MGVEVVNSGGFEVAPAPFEGKPEKNGKLDQGKGDDAPINFGSVGELPKNAEENNNKVVNSDAPKNAAEEWPVAKQIHSFYLVKYRSYADPKIKAKLDLADKELEKLNKARTGVLDKLRAKRAERSELFDLLDPLKSERKGFNTMFDEKRKEMEPLQQALGKLRSNDGGSARGPAICSSEEELNSMIYSYQYRIQHESIPLTEEKQILKEIRLLEGTRDKVIANAAMRAKIKESMGQKDDIQGQVKLMGAGLDGVKKERQAISARINELSEKLKATKDEITVLENELKTVSEKRDKAYSNIHDLRRQRDETNSEYYQNRTVLNKARDLAAQKNISELEALANAEVEKFISLWCSKKNFREDYEKRILQSLDSRQLSRDGRMRNPDEKPLIAPEAAPSKATPSETEVVPKAKAKPQPKEEPVSAPKPDATVAQNTEKAKDAVKVKNVADDDDDEVYGLGKPQKEEKPVDAATAKEMRKQEEIAKAKQAMERKKKLAEKAAAKAAIRAQKEAEKKEKKEQEKKAKKKTGGNTETETEEVPEASEEEIEAPVQEEKPQKEKVFKEKPIRNRTRGRGPETIPRAILKRKKSTNYWVYAAPAALVVLLLLVLGYYYVL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	Phosphorylation	MGVEVVNSGGFEVAP CCCEEECCCCCEEEC		27288362
42	Phosphorylation	DAPINFGSVGELPKN CCCCCCCCCCCCCCC		23111157
164	Phosphorylation	QALGKLRSNDGGSAR HHHHHHHCCCCCCCC		29654922
169	Phosphorylation	LRSNDGGSARGPAIC HHCCCCCCCCCCEEC		25561503
197	Phosphorylation	QYRIQHESIPLTEEK HHHHCCCCCCCCHHH		23111157
399	Phosphorylation	EAAPSKATPSETEVV CCCCCCCCCCCCCCC		27288362
401	Phosphorylation	APSKATPSETEVVPK CCCCCCCCCCCCCCC		27288362
403	Phosphorylation	SKATPSETEVVPKAK CCCCCCCCCCCCCHH		27288362
421	Phosphorylation	QPKEEPVSAPKPDAT CCCCCCCCCCCCCCC		19880383
525	Phosphorylation	EKKAKKKTGGNTETE HHHHHHHCCCCCCCC		23776212
529	Phosphorylation	KKKTGGNTETETEEV HHHCCCCCCCCCCCC		27532006
531	Phosphorylation	KTGGNTETETEEVPE HCCCCCCCCCCCCCC		23776212
533	Phosphorylation	GGNTETETEEVPEAS CCCCCCCCCCCCCCC		15308754
540	Phosphorylation	TEEVPEASEEEIEAP CCCCCCCCHHHCCCC		30291188

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PPI1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PPI1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PPI1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SUMO3_ARATH	SUMO3	physical	20855607

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.