PEX14_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PEX14_SCHPO
• UniProt AC: O60065
• Protein Name: Peroxisomal membrane protein pex14
• Gene Name: pex14
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 286
• Subcellular Localization: Peroxisome membrane ; Peripheral membrane protein ; Cytoplasmic side .
• Protein Description: Component of the peroxisomal translocation machinery with pex13 and pex17..
• Protein Sequence: MREDLLRNSVEFLREKTVLDAPDVKKIEFLKSKGLTAEEIQEAFKLAKNPLFPSYPRFENTSNFVSRDWRDWFIMGVISTGFAWSAYSLVKKYIAPMFRAPSQNAYEADKNALDAKFLEAHKILENLDEQTRKLSERTEKQQDELDIALDDLEETLNTLKRTSENRDREIARISQDVYTMSTITLPQSLEQIKKSQEEALQNLSREISSLRCLQTDSKKDDTFATTSNSSIPVLENPLDTSEGFQTKKVGTASLPDWQISMHNEASKNIDFNDIDPAESYVAEDAY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Phosphorylation	REDLLRNSVEFLREK CHHHHHHHHHHHHHC	19.31	25720772
102	Phosphorylation	APMFRAPSQNAYEAD HHHHCCCCCCHHHHH	34.77	25720772
222	Phosphorylation	TDSKKDDTFATTSNS CCCCCCCCEEECCCC	25.88	29996109
225	Phosphorylation	KKDDTFATTSNSSIP CCCCCEEECCCCCCE	26.94	24763107
226	Phosphorylation	KDDTFATTSNSSIPV CCCCEEECCCCCCEE	23.60	25720772
227	Phosphorylation	DDTFATTSNSSIPVL CCCEEECCCCCCEEE	30.29	29996109
229	Phosphorylation	TFATTSNSSIPVLEN CEEECCCCCCEEECC	29.43	25720772
230	Phosphorylation	FATTSNSSIPVLENP EEECCCCCCEEECCC	34.85	25720772
253	Phosphorylation	TKKVGTASLPDWQIS CCCCCCCCCCCCEEE	40.03	29996109
260	Phosphorylation	SLPDWQISMHNEASK CCCCCEEECCCHHHC	10.01	29996109
279	Phosphorylation	NDIDPAESYVAEDAY CCCCHHHHHCCCCCC	27.32	24763107

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PEX14_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PEX14_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PEX14_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
COG4_SCHPO	cog4	physical	23695164
PEP12_SCHPO	pep12	physical	26771498
COG4_SCHPO	cog4	physical	26771498

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.