PEPT1_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PEPT1_DROME
• UniProt AC: P91679
• Protein Name: Peptide transporter family 1
• Gene Name: yin
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 743
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Description: Important role in absorption of dietary peptides. High-affinity transporter of alanylalanine. Dipeptide transport activity is proton dependent..
• Protein Sequence: MASEITNGKNGQNGKNGQKEESDSQIAPPIPYPKSVAFIISNEFCERFNYYGMRTILVLYLTNKLGYNEETATVLFHTFTMLVYIFPLIGALIADGWLGKYKTILYLSLVYSLGAMVVSFGAVPLSGMPTKAVTVVGLLLIAIGTGGIKPCVSAFGGDQFSLPAQSFQLAKFFSLFYFAINAGSLISTTFTPILRADVHCFGDQDCFSLAFGVPAILMIFSVIIFMAGKRLYRCQPPAGNMIFGVSRCIADAFKGWQKRRHSEPMESFLDYAKPTVGSRMVQETKCLGRILRLFLPFPVFWALFDQQGSRWTFQATRMDGNVLGFQIKPDQMQVVNPLLILGFLPLFDYIIYPALARCGIRRPLQKLTLGLLLAALGFFLSAGLEMKMEQAAYRATPIEPDMTHLRIYNGMPCRYEISSAVVQTPRVIEPLNVWEDLSLQMTESKEYTFNAQPVSGECPSIIDKLRLQPGKSVSYFLAQDKLVEFADGLQMAATDTGRTSVRALLNTPDGEGPVLLSTESATSQEPPLTLDKGNVPQLHRITPGFARVDINGKKVASFEAKEGRLYSILVTGSARDGYQHNVIEVVALSTVSILWQLPQIVVMTAAEVMFSVTGLEFSYSQSPPSMKSVLQACWLLSVAIGNMLVVVIAEFKFTSSQSGEFTLFASLMLVDMMIFLWLARSYQYKDQREDFEDDDDATIDSVMQSKPKATTVDTTARKTNGIEAEPGYGAYRNHAYDNDFSEA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
22	Phosphorylation	KNGQKEESDSQIAPP CCCCCCCCCCCCCCC	43.59	29892262
24	Phosphorylation	GQKEESDSQIAPPIP CCCCCCCCCCCCCCC	32.53	29892262
262	Phosphorylation	GWQKRRHSEPMESFL HHHHHCCCCCCHHHH	41.40	19429919
271	Phosphorylation	PMESFLDYAKPTVGS CCHHHHHHHCCCCCH	20.76	18281928
728	Phosphorylation	GIEAEPGYGAYRNHA CCCCCCCCCCCCCCC	14.86	18281928
731	Phosphorylation	AEPGYGAYRNHAYDN CCCCCCCCCCCCCCC	13.95	18281928
736	Phosphorylation	GAYRNHAYDNDFSEA CCCCCCCCCCCCCCC	14.02	18281928

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PEPT1_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PEPT1_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PEPT1_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SGO1_DROME	mei-S332	physical	14605208

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.