| UniProt ID | PCDBE_HUMAN | |
|---|---|---|
| UniProt AC | Q9Y5E9 | |
| Protein Name | Protocadherin beta-14 | |
| Gene Name | PCDHB14 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 798 | |
| Subcellular Localization |
Cell membrane Single-pass type I membrane protein. |
|
| Protein Description | Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.. | |
| Protein Sequence | MEIRGALDLRKRQVLIFLVLLGLSRAGTESAHYSVAEETEIGSFVANLARDLGLGVEELSSREARVVSDDNKKYLHLDLLTGNLLLNEKLDRDELCGSTEPCVLHFQVVLENPLQFFRFELCVKDINDHSPTFLDKEILIKISEGTTVGATFLMESAQDLDVGSNSLQNYTISPNSHFYIKIPDSSDRKIYPELVLDRALDYEQEAELRLTLTAVDGGSPPKSGTTLVLIKVLDINDNAPEFPQSLYEVQVPEDRPLGSWIATISAKDLDAGNYGKISYTFFHASEDIRKTFEINPISGEVNLRSPLDFEVIQSYTINIQATDGGGLSGKCTLLVKVMDINDNPPEVTISSITKRIPENASETLVALFSILDQDSGDNGRMICSIQDNLPFFLKPTFKNFFTLVSEKALDRESQAEYNITITVTDLGTPRLKTEYNITVLLSDVNDNAPTFTQTSYTLFVRENNSPALHIGSVSATDRDSGTNAQVNYSLLPPQDRHLPLASLVSINADNGHLFALRSLDYEALQEFEFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHVLLVDGFSQPYLPLPEAAPAQAQADSLTVYLVVALASVSSLFLFSVLLFVAVRLCRRSRAASVGRCSVPEGPFPGHLVDVSGTGTLSQSYQYEVCLTGGSGTNEFKFLKPIIPNFQVHDTGRNMGEIENFRNSFGLNIQ | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 33 | Phosphorylation | AGTESAHYSVAEETE CCCCCCCCCCCCHHH | 12.45 | 21253578 | |
| 169 | N-linked_Glycosylation | VGSNSLQNYTISPNS CCCCCCCCEEECCCC | 41.00 | UniProtKB CARBOHYD | |
| 202 | Phosphorylation | VLDRALDYEQEAELR HHHHHCCHHHHHEEE | 21.99 | 19658100 | |
| 219 | Phosphorylation | LTAVDGGSPPKSGTT EEEECCCCCCCCCCE | 43.49 | - | |
| 359 | N-linked_Glycosylation | ITKRIPENASETLVA HHCCCCCCHHHHHHH | 43.33 | UniProtKB CARBOHYD | |
| 418 | N-linked_Glycosylation | RESQAEYNITITVTD CHHHCEEEEEEEEEE | 19.21 | UniProtKB CARBOHYD | |
| 436 | N-linked_Glycosylation | PRLKTEYNITVLLSD CCCEEEEEEEEEEEC | 19.75 | UniProtKB CARBOHYD | |
| 487 | N-linked_Glycosylation | SGTNAQVNYSLLPPQ CCCCCEEEEECCCCC | 14.48 | UniProtKB CARBOHYD | |
| 567 | N-linked_Glycosylation | FVLYPLQNGSAPCTE EEEEECCCCCCCCCC | 54.81 | UniProtKB CARBOHYD | |
| 765 | Ubiquitination | GSGTNEFKFLKPIIP CCCCCCEEECCCCCC | 43.54 | 23000965 | |
| 768 | Ubiquitination | TNEFKFLKPIIPNFQ CCCEEECCCCCCCEE | 36.98 | 23000965 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PCDBE_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PCDBE_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PCDBE_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| RBY1F_HUMAN | RBMY1F | physical | 25416956 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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