PAL2_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PAL2_ARATH
• UniProt AC: P45724
• Protein Name: Phenylalanine ammonia-lyase 2
• Gene Name: PAL2
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 717
• Subcellular Localization: Cytoplasm .
• Protein Description: This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton..
• Protein Sequence: MDQIEAMLCGGGEKTKVAVTTKTLADPLNWGLAADQMKGSHLDEVKKMVEEYRRPVVNLGGETLTIGQVAAISTVGGSVKVELAETSRAGVKASSDWVMESMNKGTDSYGVTTGFGATSHRRTKNGTALQTELIRFLNAGIFGNTKETCHTLPQSATRAAMLVRVNTLLQGYSGIRFEILEAITSLLNHNISPSLPLRGTITASGDLVPLSYIAGLLTGRPNSKATGPDGESLTAKEAFEKAGISTGFFDLQPKEGLALVNGTAVGSGMASMVLFEANVQAVLAEVLSAIFAEVMSGKPEFTDHLTHRLKHHPGQIEAAAIMEHILDGSSYMKLAQKVHEMDPLQKPKQDRYALRTSPQWLGPQIEVIRQATKSIEREINSVNDNPLIDVSRNKAIHGGNFQGTPIGVSMDNTRLAIAAIGKLMFAQFSELVNDFYNNGLPSNLTASSNPSLDYGFKGAEIAMASYCSELQYLANPVTSHVQSAEQHNQDVNSLGLISSRKTSEAVDILKLMSTTFLVGICQAVDLRHLEENLRQTVKNTVSQVAKKVLTTGINGELHPSRFCEKDLLKVVDREQVFTYVDDPCSATYPLMQRLRQVIVDHALSNGETEKNAVTSIFQKIGAFEEELKAVLPKEVEAARAAYGNGTAPIPNRIKECRSYPLYRFVREELGTKLLTGEKVVSPGEEFDKVFTAMCEGKLIDPLMDCLKEWNGAPIPIC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
106	Phosphorylation	MESMNKGTDSYGVTT HHHCCCCCCCCCCCC	24.31	30407730
108	Phosphorylation	SMNKGTDSYGVTTGF HCCCCCCCCCCCCCC	24.51	30407730
109	Phosphorylation	MNKGTDSYGVTTGFG CCCCCCCCCCCCCCC	20.58	30407730
112	Phosphorylation	GTDSYGVTTGFGATS CCCCCCCCCCCCCCC	19.48	30407730
204	"2,3-didehydroalanine (Ser)"	LRGTITASGDLVPLS CCCEEEECCCEEEHH	24.96	-
204	Other	LRGTITASGDLVPLS CCCEEEECCCEEEHH	24.96	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PAL2_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PAL2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PAL2_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SP1L4_ARATH	SP1L4	physical	21798944
SKI20_ARATH	AT3G59940	physical	21798944
PAL2_ARATH	PAL2	physical	21798944

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.