PAL1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PAL1_ARATH
• UniProt AC: P35510
• Protein Name: Phenylalanine ammonia-lyase 1
• Gene Name: PAL1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 725
• Subcellular Localization: Cytoplasm .
• Protein Description: This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton..
• Protein Sequence: MEINGAHKSNGGGVDAMLCGGDIKTKNMVINAEDPLNWGAAAEQMKGSHLDEVKRMVAEFRKPVVNLGGETLTIGQVAAISTIGNSVKVELSETARAGVNASSDWVMESMNKGTDSYGVTTGFGATSHRRTKNGVALQKELIRFLNAGIFGSTKETSHTLPHSATRAAMLVRINTLLQGFSGIRFEILEAITSFLNNNITPSLPLRGTITASGDLVPLSYIAGLLTGRPNSKATGPNGEALTAEEAFKLAGISSGFFDLQPKEGLALVNGTAVGSGMASMVLFETNVLSVLAEILSAVFAEVMSGKPEFTDHLTHRLKHHPGQIEAAAIMEHILDGSSYMKLAQKLHEMDPLQKPKQDRYALRTSPQWLGPQIEVIRYATKSIEREINSVNDNPLIDVSRNKAIHGGNFQGTPIGVSMDNTRLAIAAIGKLMFAQFSELVNDFYNNGLPSNLTASRNPSLDYGFKGAEIAMASYCSELQYLANPVTSHVQSAEQHNQDVNSLGLISSRKTSEAVDILKLMSTTFLVAICQAVDLRHLEENLRQTVKNTVSQVAKKVLTTGVNGELHPSRFCEKDLLKVVDREQVYTYADDPCSATYPLIQKLRQVIVDHALINGESEKNAVTSIFHKIGAFEEELKAVLPKEVEAARAAYDNGTSAIPNRIKECRSYPLYRFVREELGTELLTGEKVTSPGEEFDKVFTAICEGKIIDPMMECLNEWNGAPIPIC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
114	Phosphorylation	MESMNKGTDSYGVTT HHHCCCCCCCCCCCC	24.31	30407730
116	Phosphorylation	SMNKGTDSYGVTTGF HCCCCCCCCCCCCCC	24.51	30407730
117	Phosphorylation	MNKGTDSYGVTTGFG CCCCCCCCCCCCCCC	20.58	30407730
120	Phosphorylation	GTDSYGVTTGFGATS CCCCCCCCCCCCCCC	19.48	30407730
152	Phosphorylation	LNAGIFGSTKETSHT HHCCCCCCCCCCCCC	26.09	23328941
163	Phosphorylation	TSHTLPHSATRAAML CCCCCCCHHHHHHHH	29.42	19880383
212	"2,3-didehydroalanine (Ser)"	LRGTITASGDLVPLS CCCEEEECCCEEEHH	24.96	-
212	Other	LRGTITASGDLVPLS CCCEEEECCCEEEHH	24.96	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PAL1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PAL1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PAL1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PAL4_ARATH	PAL4	physical	21798944
PAL1_ARATH	PAL1	physical	21798944
SKI20_ARATH	AT3G59940	physical	21798944

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.