PA216_HUMAN - dbPTM
PA216_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PA216_HUMAN
UniProt AC P53816
Protein Name HRAS-like suppressor 3 {ECO:0000303|PubMed:17374643}
Gene Name PLA2G16 {ECO:0000312|HGNC:HGNC:17825}
Organism Homo sapiens (Human).
Sequence Length 162
Subcellular Localization Membrane
Single-pass membrane protein . Cytoplasm . Cytoplasm, perinuclear region . Peroxisome membrane .
Protein Description Lipid-modifying enzyme that acts as major regulator of adipocyte lipolysis by catalyzing the release of fatty acids from phospholipids in adipose tissue. [PubMed: 19615464]
Protein Sequence MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIVKKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNELRYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of PA216_HUMAN !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PA216_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PA216_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PA216_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
UBQL1_HUMANUBQLN1physical
16189514
2AAA_HUMANPPP2R1Aphysical
17374643
UBQL1_HUMANUBQLN1physical
25416956
RASH_HUMANHRASphysical
24884338

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PA216_HUMAN

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Related Literatures of Post-Translational Modification

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