dbPTM

ODD_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ODD_DROME
UniProt AC	P23803
Protein Name	Protein odd-skipped
Gene Name	odd
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	392
Subcellular Localization	Nucleus .
Protein Description	Pair-rule protein that determines both the size and polarity of even-numbered as well as odd-numbered parasegments during embryogenesis. DNA-binding transcription factor that acts primarily as a transcriptional repressor but can also function as a transcriptional activator, depending on the stage of development and spatial restrictions. May function redundantly with odd and drm in leg joint formation during the larval stages, acting downstream of Notch activation..
Protein Sequence	MSSTSASPISNITVDDELNLSREQDFAEEDFIVIKEERETSLSPMLTPPHTPTEEPLRRVHPAISEEAVATQLHMRHMAHYQQQQQQQQQQQQHRLWLQMQQQQQQHQAPQQYPVYPTASADPVAVHQQLMNHWIRNAAIYQQQQQQQQHPHHHHHHGHPHHPHPHPHHVRPYPAGLHSLHAAVMGRHFGAMPTLKLGGAGGASGVPSGATGSSRPKKQFICKYCNRQFTKSYNLLIHERTHTDERPYSCDICGKAFRRQDHLRDHRYIHSKDKPFKCSDCGKGFCQSRTLAVHKVTHLEEGPHKCPICQRSFNQRANLKSHLQSHSEQSTKEVVVTTSPATSHSVPNQALSSPQPENLAQHLPVLDLSSSSSSSEKPKRMLGFTIDEIMSR

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
2	Phosphorylation	------MSSTSASPI ------CCCCCCCCC	42.18	22668510
21	Phosphorylation	VDDELNLSREQDFAE CCCCCCCCCCCCCCC	32.47	22668510

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ODD_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ODD_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ODD_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
RG92B_DROME	RhoGAP92B	physical	14605208
U428_DROME	CG16865	physical	25242320

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ODD_DROME

Related Literatures of Post-Translational Modification