NXPE3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NXPE3_HUMAN
• UniProt AC: Q969Y0
• Protein Name: NXPE family member 3
• Gene Name: NXPE3
• Organism: Homo sapiens (Human).
• Sequence Length: 559
• Subcellular Localization: Secreted .
• Protein Sequence: MWTNFFKLRLFCCLLAVLMVVVLVINVTQVEYLDHETVSATFIDSSGQFVSSQVTGISRNPYCGYDQQTLSSQERMEEDSLLAALHRQVPDVGPVPFVKSTDPSSSYFVILNSAAFFKVGSQLEVLVHVQDFQRKPKKYGGDYLQARIHSLKLQAGAVGRVVDYQNGFYKVFFTLLWPGKVKVSVSLVHPSEGIRVLQRLQEDKPDRVYFKSLFRSGRISETTECNVCLPGNLPLCNFTDLYTGEPWFCFKPKKLPCSSRITHFKGGYLKGLLTAAESAFFQSGVNIKMPVNSSGPDWVTVIPRRIKETNSLELSQGSGTFPSGYYYKDQWRPRKFKMRQFNDPDNITECLQRKVVHLFGDSTIRQWFEYLTTFVPDLVEFNLGSPKNVGPFLAVDQKHNILLKYRCHGPPIRFTTVFSNELHYVANELNGIVGGKNTVVAIAVWSHFSTFPLEVYIRRLRNIRRAVVRLLDRSPKTVVVIRTANAQELGPEVSLFNSDWYNFQLDTILRRMFSGVGVYLVDAWEMTLAHYLPHKLHPDEVIVKNQLDMFLSFVCPLET

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
26	N-linked_Glycosylation	MVVVLVINVTQVEYL HHHHHHHCCCCCEEC		UniProtKB CARBOHYD
51	O-linked_Glycosylation	DSSGQFVSSQVTGIS CCCCCEEEEEEECCC		OGP
121	Phosphorylation	AAFFKVGSQLEVLVH CEEEECCCEEEEEEE		-
184	Phosphorylation	WPGKVKVSVSLVHPS CCCEEEEEEEEECCC		-
191	Phosphorylation	SVSLVHPSEGIRVLQ EEEEECCCHHHHHHH		-
211	Ubiquitination	KPDRVYFKSLFRSGR CCCCEEEHHHHHCCC		-
237	N-linked_Glycosylation	PGNLPLCNFTDLYTG CCCCCCCCCCCCCCC		UniProtKB CARBOHYD
292	N-linked_Glycosylation	VNIKMPVNSSGPDWV CCEEECCCCCCCCCE		UniProtKB CARBOHYD
320	Phosphorylation	ELSQGSGTFPSGYYY EECCCCCCCCCCCCC		19690332
323	Phosphorylation	QGSGTFPSGYYYKDQ CCCCCCCCCCCCCCC		22817900
327	Phosphorylation	TFPSGYYYKDQWRPR CCCCCCCCCCCCCCC		19690332
346	N-linked_Glycosylation	RQFNDPDNITECLQR CCCCCCCCHHHHHHH		UniProtKB CARBOHYD
474	Phosphorylation	VVRLLDRSPKTVVVI HHHHHCCCCCEEEEE		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NXPE3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NXPE3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NXPE3_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.