NPR3_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NPR3_ARATH
• UniProt AC: Q8L746
• Protein Name: Regulatory protein NPR3
• Gene Name: NPR3
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 586
• Subcellular Localization: Nucleus .
• Protein Description: May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Involved in the regulation of basal defense responses against pathogens..
• Protein Sequence: MATLTEPSSSLSFTSSHFSYGSIGSNHFSSSSASNPEVVSLTKLSSNLEQLLSNSDCDYSDAEIIVDGVPVGVHRCILAARSKFFQDLFKKEKKISKTEKPKYQLREMLPYGAVAHEAFLYFLSYIYTGRLKPFPLEVSTCVDPVCSHDCCRPAIDFVVQLMYASSVLQVPELVSSFQRRLCNFVEKTLVENVLPILMVAFNCKLTQLLDQCIERVARSDLYRFCIEKEVPPEVAEKIKQLRLISPQDEETSPKISEKLLERIGKILKALDSDDVELVKLLLTESDITLDQANGLHYSVVYSDPKVVAEILALDMGDVNYRNSRGYTVLHFAAMRREPSIIISLIDKGANASEFTSDGRSAVNILRRLTNPKDYHTKTAKGRESSKARLCIDILEREIRKNPMVLDTPMCSISMPEDLQMRLLYLEKRVGLAQLFFPTEAKVAMDIGNVEGTSEFTGLSPPSSGLTGNLSQVDLNETPHMQTQRLLTRMVALMKTVETGRRFFPYGSEVLDKYMAEYIDDDILDDFHFEKGSTHERRLKRMRYRELKDDVQKAYSKDKESKIARSCLSASSSPSSSSIRDDLHNTT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
10	Phosphorylation	TLTEPSSSLSFTSSH CCCCCCCCCEEECCC	32.16	-
570	Phosphorylation	ARSCLSASSSPSSSS HHHHHHCCCCCCCHH	28.15	28295753
574	Phosphorylation	LSASSSPSSSSIRDD HHCCCCCCCHHHHHH	44.81	28295753
575	Phosphorylation	SASSSPSSSSIRDDL HCCCCCCCHHHHHHH	31.33	28295753
576	Phosphorylation	ASSSPSSSSIRDDLH CCCCCCCHHHHHHHC	33.84	28295753

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NPR3_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NPR3_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NPR3_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TGA2_ARATH	AHBP-1B	physical	17076807
TGA3_ARATH	TGA3	physical	17076807
TGA5_ARATH	OBF5	physical	17076807
TGA6_ARATH	TGA6	physical	17076807
TGA2_ARATH	AHBP-1B	physical	22986789

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.