dbPTM

NMUR1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NMUR1_HUMAN
UniProt AC	Q9HB89
Protein Name	Neuromedin-U receptor 1
Gene Name	NMUR1
Organism	Homo sapiens (Human).
Sequence Length	426
Subcellular Localization	Cell membrane Multi-pass membrane protein.
Protein Description	Receptor for the neuromedin-U and neuromedin-S neuropeptides..
Protein Sequence	MTPLCLNCSVLPGDLYPGGARNPMACNGSAARGHFDPEDLNLTDEALRLKYLGPQQTELFMPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYEMWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRRVLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALLFFCLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLFVLVVVFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANPVLYSLMSSRFRETFQEALCLGACCHRLRPRHSSHSLSRMTTGSTLCDVGSLGSWVHPLAGNDGPEAQQETDPS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	N-linked_Glycosylation	-MTPLCLNCSVLPGD -CCCCEECCEECCCC	18.28	UniProtKB CARBOHYD
27	N-linked_Glycosylation	ARNPMACNGSAARGH CCCCCCCCCCCCCCC	37.61	UniProtKB CARBOHYD
41	N-linked_Glycosylation	HFDPEDLNLTDEALR CCCHHHCCCCCHHHH	53.90	UniProtKB CARBOHYD
156	Phosphorylation	VLNVTALSVERYVAV HHHHHCCCHHHHHEE	21.33	24719451
160	Phosphorylation	TALSVERYVAVVHPL HCCCHHHHHEECCHH	4.54	-
171	Phosphorylation	VHPLQARSMVTRAHV CCHHHHHHHHHHHHH	22.18	29900121
174	Phosphorylation	LQARSMVTRAHVRRV HHHHHHHHHHHHHHH	17.31	29900121

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NMUR1_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NMUR1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NMUR1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
NMU_HUMAN	NMU	physical	10899166

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NMUR1_HUMAN

Related Literatures of Post-Translational Modification