| UniProt ID | NMD3_MOUSE | |
|---|---|---|
| UniProt AC | Q99L48 | |
| Protein Name | 60S ribosomal export protein NMD3 | |
| Gene Name | Nmd3 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 503 | |
| Subcellular Localization | Cytoplasm . Nucleus . Shuttles between the nucleus/nucleolus and the cytoplasm in a XPO1/CRM1-dependent manner. | |
| Protein Description | Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.. | |
| Protein Sequence | MEYMAESIEHSPGHILCCECGVPISPNPANICVACLRSKVDISQGVPKQVSISFCKQCQRYFQPPASWVQCALESRELLALCLKKIKAPLSKVRLVDAGFVWTEPHSKRLKVKLTIQKEVMNGAILQQVFVVDYVVQSQMCGDCHRVEAKDFWKAVIQVRQKTLHKKTFYYLEQLILKYGMHQNTLRIKEIHDGLDFYYSSKQHAQKMVEFLQGIVPCRYKASQRLISQDIHSNTYNYKSTFSVEIVPICKDNVVCLSPKLAQSLGNMSQICICIRVTSAIHLIDPNTLQVADIDGNTFWSHPFNSLCHPKQLEEFIVIECSTVRDLKRSAGAGVISKKHTLGEVWIQKTSEMNTDKQYFCRTHLGHLLNPGDLVLGFDLANCNLNDEYVNKMNSDRVPDVVLIKKSYDRTKRQRRRNWKLKELARDRENMDTDDERQYQDFLEDLEEDEAIRKHVNIYRDATIPVESDTDDEGAPRISLAEMLEDLHISQDATGEEGASMMS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 1 | Acetylation | -------MEYMAESI -------CCCCHHHC | 8.21 | - | |
| 3 | Phosphorylation | -----MEYMAESIEH -----CCCCHHHCCC | 10.59 | 26745281 | |
| 7 | Phosphorylation | -MEYMAESIEHSPGH -CCCCHHHCCCCCCE | 24.60 | 26745281 | |
| 11 | Phosphorylation | MAESIEHSPGHILCC CHHHCCCCCCEEEEE | 21.56 | 26745281 | |
| 25 | Phosphorylation | CECGVPISPNPANIC EECCCCCCCCHHHHH | 16.74 | 26824392 | |
| 179 | Phosphorylation | LEQLILKYGMHQNTL HHHHHHHHCCCCCEE | 19.08 | - | |
| 218 | S-palmitoylation | FLQGIVPCRYKASQR HHHCHHHCCHHHHHH | 5.27 | 28526873 | |
| 236 | Phosphorylation | QDIHSNTYNYKSTFS CCCCCCCCCCCCEEE | 22.27 | - | |
| 258 | Phosphorylation | KDNVVCLSPKLAQSL CCCEEEECHHHHHHH | 18.18 | 21454597 | |
| 433 | Phosphorylation | RDRENMDTDDERQYQ HHHHCCCCCCHHHHH | 34.28 | 25521595 | |
| 463 | Phosphorylation | VNIYRDATIPVESDT CCEECCCCCCCCCCC | 30.06 | 25619855 | |
| 468 | Phosphorylation | DATIPVESDTDDEGA CCCCCCCCCCCCCCC | 46.15 | 27087446 | |
| 470 | Phosphorylation | TIPVESDTDDEGAPR CCCCCCCCCCCCCCC | 55.41 | 27087446 | |
| 490 | Phosphorylation | MLEDLHISQDATGEE HHHHCCCCCCCCCCC | 15.97 | 26643407 | |
| 494 | Phosphorylation | LHISQDATGEEGASM CCCCCCCCCCCCCCC | 54.11 | 26643407 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of NMD3_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of NMD3_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of NMD3_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| ES8L3_HUMAN | EPS8L3 | physical | 17124247 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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