dbPTM

NINJ1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NINJ1_HUMAN
UniProt AC	Q92982
Protein Name	Ninjurin-1
Gene Name	NINJ1
Organism	Homo sapiens (Human).
Sequence Length	152
Subcellular Localization	Membrane Multi-pass membrane protein.
Protein Description	Homophilic cell adhesion molecule that promotes axonal growth. May play a role in nerve regeneration and in the formation and function of other tissues. Cell adhesion requires divalent cations..
Protein Sequence	MDSGTEEYELNGGLPPGTPGSPDASPARWGWRHGPINVNHYASKKSAAESMLDIALLMANASQLKAVVEQGPSFAFYVPLVVLISISLVLQIGVGVLLIFLVKYDLNNPAKHAKLDFLNNLATGLVFIIVVVNIFITAFGVQKPLMDMAPQQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MDSGTEEY -------CCCCCCEE	9.26	22814378
3	Phosphorylation	-----MDSGTEEYEL -----CCCCCCEEEC	46.44	26503514
5	Phosphorylation	---MDSGTEEYELNG ---CCCCCCEEECCC	29.60	24719451
8	Phosphorylation	MDSGTEEYELNGGLP CCCCCCEEECCCCCC	21.34	27642862
18	Phosphorylation	NGGLPPGTPGSPDAS CCCCCCCCCCCCCCC	30.19	26503514
21	Phosphorylation	LPPGTPGSPDASPAR CCCCCCCCCCCCCCC	22.32	-
25	Phosphorylation	TPGSPDASPARWGWR CCCCCCCCCCCCCCC	26.86	26503514
44	Ubiquitination	NVNHYASKKSAAESM CCHHHCCHHHHHHHH	42.44	27667366
46	Phosphorylation	NHYASKKSAAESMLD HHHCCHHHHHHHHHH	36.13	-
50	Phosphorylation	SKKSAAESMLDIALL CHHHHHHHHHHHHHH	21.66	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NINJ1_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NINJ1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NINJ1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
K1C40_HUMAN	KRT40	physical	25416956

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NINJ1_HUMAN

Related Literatures of Post-Translational Modification