MYPOP_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MYPOP_MOUSE
• UniProt AC: Q8R4U1
• Protein Name: Myb-related transcription factor, partner of profilin
• Gene Name: Mypop
• Organism: Mus musculus (Mouse).
• Sequence Length: 393
• Subcellular Localization: Nucleus .
• Protein Description: Transcriptional repressor; DNA-binding protein that specifically recognizes the core sequence 5'-YAAC[GT]G-3'. Dimerization with PFN1 reduces its DNA-binding capacity..
• Protein Sequence: MASATAAAAPGEAEETTRLRKPRFSFEENQILIREVRAHYPQLYGAQSRRVSVAERRRVWDSIATKINGITSWKRTGQEVQKRWNDFKRRTKEKLARVPHSTQGAGPAAEDAFSAEEETIFAILGPGVAGPGAGSGAEESRAAASSQPQASTASTQRYVLSEDRRQDRRADTPAQSKGGSSSPESWARPSCNPQEAKERESTSPAAMQPVQLPRLALSPPLPAPPPPPTALAQVAPSSPSPTPPRPTSAPEQSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPADPLPPPPPPPPPPPPKPVLPPSAPKVELAPEPVSVVAAVVDGAVVAARGVIISPRSEEGVPKPLPPAPPLPLHDSPPHKRRKGFPTRKRRGRWKSP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MASATAAAAPGE ---CCCCCCCCCCCC	17.84	29895711
16	Phosphorylation	APGEAEETTRLRKPR CCCCHHHHHCCCCCC	14.55	22817900
17	Phosphorylation	PGEAEETTRLRKPRF CCCHHHHHCCCCCCC	30.87	22817900
48	Phosphorylation	PQLYGAQSRRVSVAE HHHHCCCCCCCCHHH	22.86	-
52	Phosphorylation	GAQSRRVSVAERRRV CCCCCCCCHHHHHHH	17.50	30482847
145	Phosphorylation	EESRAAASSQPQAST HHHHHHHHCCCCCCC	25.44	29895711
146	Phosphorylation	ESRAAASSQPQASTA HHHHHHHCCCCCCCH	40.95	29895711
151	Phosphorylation	ASSQPQASTASTQRY HHCCCCCCCHHHHHE	21.18	29895711
152	Phosphorylation	SSQPQASTASTQRYV HCCCCCCCHHHHHEE	27.87	29895711
154	Phosphorylation	QPQASTASTQRYVLS CCCCCCHHHHHEECC	25.76	29895711
155	Phosphorylation	PQASTASTQRYVLSE CCCCCHHHHHEECCC	18.01	29895711
180	Phosphorylation	PAQSKGGSSSPESWA CCCCCCCCCCHHHCC	35.99	28066266
181	Phosphorylation	AQSKGGSSSPESWAR CCCCCCCCCHHHCCC	53.86	28066266
182	Phosphorylation	QSKGGSSSPESWARP CCCCCCCCHHHCCCC	34.09	28066266
185	Phosphorylation	GGSSSPESWARPSCN CCCCCHHHCCCCCCC	29.44	28066266
201	Phosphorylation	QEAKERESTSPAAMQ HHHHHHHCCCCHHCC	40.17	25293948
202	Phosphorylation	EAKERESTSPAAMQP HHHHHHCCCCHHCCC	33.70	25293948
203	Phosphorylation	AKERESTSPAAMQPV HHHHHCCCCHHCCCC	23.09	25293948
240	Phosphorylation	QVAPSSPSPTPPRPT HCCCCCCCCCCCCCC	43.27	23384938
242	Phosphorylation	APSSPSPTPPRPTSA CCCCCCCCCCCCCCC	50.71	23384938
372	Phosphorylation	PPLPLHDSPPHKRRK CCCCCCCCCCCCCCC	29.59	26745281
383	Phosphorylation	KRRKGFPTRKRRGRW CCCCCCCCCCCCCCC	46.70	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MYPOP_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MYPOP_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MYPOP_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MYPOP_MOUSE	Mypop	physical	15615774

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.