MYG_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MYG_HUMAN
• UniProt AC: P02144
• Protein Name: Myoglobin
• Gene Name: MB
• Organism: Homo sapiens (Human).
• Sequence Length: 154
• Protein Description: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles..
• Protein Sequence: MGLSDGEWQLVLNVWGKVEADIPGHGQEVLIRLFKGHPETLEKFDKFKHLKSEDEMKASEDLKKHGATVLTALGGILKKKGHHEAEIKPLAQSHATKHKIPVKYLEFISECIIQVLQSKHPGDFGADAQGAMNKALELFRKDMASNYKELGFQG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MGLSDGEWQLV ----CCCCCCCEEEE	37.53	22673903
17	Acetylation	LVLNVWGKVEADIPG EEEEEEEEEEECCCC	22.61	90235
40	Phosphorylation	LFKGHPETLEKFDKF HHCCCHHHHHHHHHC	44.67	26437602
46	Acetylation	ETLEKFDKFKHLKSE HHHHHHHHCCCCCCH	60.49	24885839
48	Acetylation	LEKFDKFKHLKSEDE HHHHHHCCCCCCHHH	54.49	7822159
51	Acetylation	FDKFKHLKSEDEMKA HHHCCCCCCHHHHHH	52.06	7821827
52	Phosphorylation	DKFKHLKSEDEMKAS HHCCCCCCHHHHHHC	57.55	26437602
57	Acetylation	LKSEDEMKASEDLKK CCCHHHHHHCHHHHH	46.87	156167
59	Phosphorylation	SEDEMKASEDLKKHG CHHHHHHCHHHHHHC	26.56	19764811
63	Acetylation	MKASEDLKKHGATVL HHHCHHHHHHCHHHH	55.86	156263
64	Acetylation	KASEDLKKHGATVLT HHCHHHHHHCHHHHH	55.35	155979
68	Phosphorylation	DLKKHGATVLTALGG HHHHHCHHHHHHHHH	22.20	29396449
71	Phosphorylation	KHGATVLTALGGILK HHCHHHHHHHHHHHH	18.59	29396449
78	Acetylation	TALGGILKKKGHHEA HHHHHHHHHCCCCCC	50.98	7923437
93	Phosphorylation	EIKPLAQSHATKHKI CHHHHHHHHCCCCCC	14.96	26437602
96	Phosphorylation	PLAQSHATKHKIPVK HHHHHHCCCCCCCHH	28.40	26437602
104	Phosphorylation	KHKIPVKYLEFISEC CCCCCHHHHHHHHHH	16.23	26437602
104	Nitration	KHKIPVKYLEFISEC CCCCCHHHHHHHHHH	16.23	-
109	Phosphorylation	VKYLEFISECIIQVL HHHHHHHHHHHHHHH	31.56	26437602
118	Phosphorylation	CIIQVLQSKHPGDFG HHHHHHHCCCCCCCC	28.86	26437602
145	Phosphorylation	LFRKDMASNYKELGF HHHHHHHHHHHHHCC	33.77	19764811
147	Phosphorylation	RKDMASNYKELGFQG HHHHHHHHHHHCCCC	11.89	19764811
147	Nitration	RKDMASNYKELGFQG HHHHHHHHHHHCCCC	11.89	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MYG_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MYG_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MYG_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
ANK1_HUMAN	ANK1	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.