MYCB2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MYCB2_HUMAN
• UniProt AC: O75592
• Protein Name: E3 ubiquitin-protein ligase MYCBP2 {ECO:0000305}
• Gene Name: MYCBP2 {ECO:0000312|HGNC:HGNC:23386}
• Organism: Homo sapiens (Human).
• Sequence Length: 4678
• Subcellular Localization: Nucleus . Cell projection, axon . Cytoplasm, cytoskeleton . Localizes to axon shafts and associates with microtubule cytoskeleton (By similarity). Translocates to the nucleus following interaction with sumoylated RANGAP1 (PubMed:26304119).
• Protein Description: Atypical E3 ubiquitin-protein ligase which specifically mediates ubiquitination of threonine and serine residues on target proteins, instead of ubiquitinating lysine residues. [PubMed: 29643511 Shows esterification activity towards both threonine and serine, with a preference for threonine, and acts via two essential catalytic cysteine residues that relay ubiquitin to its substrate via thioester intermediates]
• Protein Sequence: MMMCAATASPAAASSGLGGDGFYPAATFSSSPAPGALFMPVPDGSVAAAGLGLGLPAADSRGHYQLLLSGRALADRYRRIYTAALNDRDQGGGSAGHPASRNKKILNKKKLKRKQKSKSKVKTRSKSENLENTVIIPDIKLHSNPSAFNIYCNVRHCVLEWQKKEISLAAASKNSVQSGESDSDEEEESKEPPIKLPKIIEVGLCEVFELIKETRFSHPSLCLRSLQALLNVLQGQQPEGLQSEPPEVLESLFQLLLEITVRSTGMNDSTGQSLTALSCACLFSLVASWGETGRTLQAISAILTNNGSHACQTIQVPTILNSLQRSVQAVLVGKIQIQDWFSNGIKKAALMHKWPLKEISVDEDDQCLLQNDGFFLYLLCKDGLYKIGSGYSGTVRGHIYNSTSRIRNRKEKKSWLGYAQGYLLYRDVNNHSMTAIRISPETLEQDGTVMLPDCHTEGQNILFTDGEYINQIAASRDDGFVVRIFATSTEPVLQQELQLKLARKCLHACGISLFDLEKDLHIISTGFDEESAILGAGREFALMKTANGKIYYTGKYQSLGIKQGGPSAGKWVELPITKSPKIVHFSVGHDGSHALLVAEDGSIFFTGSASKGEDGESTKSRRQSKPYKPKKIIKMEGKIVVYTACNNGSSSVISKDGELYMFGKDAIYSDSSSLVTDLKGHFVTQVAMGKAHTCVLMKNGEVWTFGVNNKGQCGRDTGAMNQGGKGFGVENMATAMDEDLEEELDEKDEKSMMCPPGMHKWKLEQCMVCTVCGDCTGYGASCVSSGRPDRVPGGICGCGSGESGCAVCGCCKACARELDGQEARQRGILDAVKEMIPLDLLLAVPVPGVNIEEHLQLRQEEKRQRVIRRHRLEEGRGPLVFAGPIFMNHREQALARLRSHPAQLKHKRDKHKDGSGERGEKDASKITTYPPGSVRFDCELRAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQALPGPSTQVTAGSNHTAVLLMDGQVFTFGSFSKGQLGRPILDVPYWNAKPAPMPNIGSKYGRKATWIGASGDQTFLRIDEALINSHVLATSEIFASKHIIGLVPASISEPPPFKCLLINKVDGSCKTFNDSEQEDLQGFGVCLDPVYDVIWRFRPNTRELWCYNAVVADARLPSAADMQSRCSILSPELALPTGSRALTTRSHAALHILGCLDTLAAMQDLKMGVASTEEETQAVMKVYSKEDYSVVNRFESHGGGWGYSAHSVEAIRFSADTDILLGGLGLFGGRGEYTAKIKLFELGPDGGDHETDGDLLAETDVLAYDCAAREKYAMMFDEPVLLQAGWWYVAWARVSGPSSDCGSHGQASITTDDGVVFQFKSSKKSNNGTDVNAGQIPQLLYRLPTSDGSASKGKQQTSEPVHILKRSFARTVSVECFESLLSILHWSWTTLVLGVEELRGLKGFQFTATLLDLERLRFVGTCCLRLLRVYTCEIYPVSATGKAVVEETSKLAECIGKTRTLLRKILSEGVDHCMVKLDNDPQGYLSQPLSLLEAVLQECHNTFTACFHSFYPTPALQWACLCDLLNCLDQDIQEANFKTSSSRLLAAVMSALCHTSVKLTSIFPIAYDGEVLLRSIVKQVSTENDSTLVHRFPLLVAHMEKLSQSEENISGMTSFREVLEKMLVIVVLPVRNSLRRENELFSSHLVSNTCGLLASIVSELTASALGSEVDGLNSLHSVKASANRFTKTSQGRSWNTGNGSPDAICFSVDKPGIVVVGFSVYGGGGIHEYELEVLVDDSEHAGDSTHSHRWTSLELVKGTYTTDDSPSDIAEIRLDKVVPLKENVKYAVRLRNYGSRTANGDGGMTTVQCPDGVTFTFSTCSLSSNGTNQTRGQIPQILYYRSEFDGDLQSQLLSKANEEDKNCSRALSVVSTVVRASKDLLHRALAVDADDIPELLSSSSLFSMLLPLIIAYIGPVAAAIPKVAVEVFGLVQQLLPSVAILNQKYAPPAFNPNQSTDSTTGNQPEQGLSACTTSSHYAVIESEHPYKPACVMHYKVTFPECVRWMTIEFDPQCGTAQSEDVLRLLIPVRTVQNSGYGPKLTSVHENLNSWIELKKFSGSSGWPTMVLVLPGNEALFSLETASDYVKDDKASFYGFKCFAIGYEFSPGPDEGVIQLEKELANLGGVCAAALMKKDLALPIGNELEEDLEILEEAALQVCKTHSGILGKGLALSHSPTILEALEGNLPLQIQSNEQSFLDDFIACVPGSSGGRLARWLQPDSYADPQKTSLILNKDDIRCGWPTTITVQTKDQYGDVVHVPNMKVEVKAVPVSQKKMSLQQDQAKKPQRIPGSPAVTAASSNTDMTYGGLASPKLDVSYEPMIVKEARYIAITMMKVYENYSFEELRFASPTPKRPSENMLIRVNNDGTYCANWTPGAIGLYTLHVTIDGIEIDAGLEVKVKDPPKGMIPPGTQLVKPKSEPQPNKVRKFVAKDSAGLRIRSHPSLQSEQIGIVKVNGTITFIDEIHNDDGVWLRLNDETIKKYVPNMNGYTEAWCLSFNQHLGKSLLVPVDESKTNTDDFFKDINSCCPQEATMQEQDMPFLRGGPGMYKVVKTGPSGHNIRSCPNLRGIPIGMLVLGNKVKAVGEVTNSEGTWVQLDQNSMVEFCESDEGEAWSLARDRGGNQYLRHEDEQALLDQNSQTPPPSPFSVQAFNKGASCSAQGFDYGLGNSKGDRGNISTSSKPASTSGKSELSSKHSRSLKPDGRMSRTTADQKKPRGTESLSASESLILKSDAAKLRSDSHSRSLSPNHNTLQTLKSDGRMPSSSRAESPGPGSRLSSPKPKTLPANRSSPSGASSPRSSSPHDKNLPQKSTAPVKTKLDPPRERSKSDSYTLDPDTLRKKKMPLTEPLRGRSTSPKPKSVPKDSTDSPGSENRAPSPHVVQENLHSEVVEVCTSSTLKTNSLTDSTCDDSSEFKSVDEGSNKVHFSIGKAPLKDEQEMRASPKISRKCANRHTRPKKEKSSFLFKGDGSKPLEPAKQAMSPSVAECARAVFASFLWHEGIVHDAMACSSFLKFHPELSKEHAPIRSSLNSQQPTEEKETKLKNRHSLEISSALNMFNIAPHGPDISKMGSINKNKVLSMLKEPPLHEKCEDGKTETTFEMSMHNTMKSKSPLPLTLQHLVAFWEDISLATIKAASQNMIFPSPGSCAVLKKKECEKENKKSKKEKKKKEKAEVRPRGNLFGEMAQLAVGGPEKDTICELCGESHPYPVTYHMRQAHPGCGRYAGGQGYNSIGHFCGGWAGNCGDGGIGGSTWYLVCDRCREKYLREKQAAAREKVKQSRRKPMQVKTPRALPTMEAHQVIKANALFLLSLSSAAEPSILCYHPAKPFQSQLPSVKEGISEDLPVKMPCLYLQTLARHHHENFVGYQDDNLFQDEMRYLRSTSVPAPYISVTPDASPNVFEEPESNMKSMPPSLETSPITDTDLAKRTVFQRSYSVVASEYDKQHSILPARVKAIPRRRVNSGDTEVGSSLLRHPSPELSRLISAHSSLSKGERNFQWPVLAFVIQHHDLEGLEIAMKQALRKSACRVFAMEAFNWLLCNVIQTTSLHDILWHFVASLTPAPVEPEEEEDEENKTSKENSEQEKDTRVCEHPLSDIVIAGEAAHPLPHTFHRLLQTISDLMMSLPSGSSLQQMALRCWSLKFKQSDHQFLHQSNVFHHINNILSKSDDGDSEESFSISIQSGFEAMSQELCIVMCLKDLTSIVDIKTSSRPAMIGSLTDGSTETFWESGDEDKNKTKNITINCVKGINARYVSVHVDNSRDLGNKVTSMTFLTGKAVEDLCRIKQVDLDSRHIGWVTSELPGGDNHIIKIELKGPENTLRVRQVKVLGWKDGESTKIAGQISASVAQQRNCEAETLRVFRLITSQVFGKLISGDAEPTPEQEEKALLSSPEGEEKVYNATSDADLKEHMVGIIFSRSKLTNLQKQVCAHIVQAIRMEATRVREEWEHAISSKENANSQPNDEDASSDAYCFELLSMVLALSGSNVGRQYLAQQLTLLQDLFSLLHTASPRVQRQVTSLLRRVLPEVTPSRLASIIGVKSLPPADISDIIHSTEKGDWNKLGILDMFLGCIAKALTVQLKAKGTTITGTAGTTVGKGVTTVTLPMIFNSSYLRRGESHWWMKGSTPTQISEIIIKLIKDMAAGHLSEAWSRVTKNAIAETIIALTKMEEEFRSPVRCIATTRLWLALASLCVLDQDHVDRLSSGRWMGKDGQQKQMPMCDNHDDGETAAIILCNVCGNLCTDCDRFLHLHRRTKTHQRQVFKEEEEAIKVDLHEGCGRTKLFWLMALADSKTMKAMVEFREHTGKPTTSSSEACRFCGSRSGTELSAVGSVCSDADCQEYAKIACSKTHPCGHPCGGVKNEEHCLPCLHGCDKSATSLKQDADDMCMICFTEALSAAPAIQLDCSHIFHLQCCRRVLENRWLGPRITFGFISCPICKNKINHIVLKDLLDPIKELYEDVRRKALMRLEYEGLHKSEAITTPGVRFYNDPAGYAMNRYAYYVCYKCRKAYFGGEARCDAEAGRGDDYDPRELICGACSDVSRAQMCPKHGTDFLEYKCRYCCSVAVFFCFGTTHFCNACHDDFQRMTSIPKEELPHCPAGPKGKQLEGTECPLHVVHPPTGEEFALGCGVCRNAHTF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
26	Phosphorylation	GDGFYPAATFSSSPA CCCCCCCCEECCCCC	12.04	22817900
31	Phosphorylation	PAATFSSSPAPGALF CCCEECCCCCCCCEE	26.63	29214152
39	Phosphorylation	PAPGALFMPVPDGSV CCCCCEEEECCCCCC	12.56	22817900
56	Phosphorylation	AGLGLGLPAADSRGH CCCCCCCCCCCCCCH	34.06	28555341
69	Phosphorylation	GHYQLLLSGRALADR CHHHHHHCCHHHHHH	58.54	-
87	Phosphorylation	IYTAALNDRDQGGGS HHHHHCCCCCCCCCC	45.85	23186163
88	Ubiquitination	YTAALNDRDQGGGSA HHHHCCCCCCCCCCC	59.50	-
89	Phosphorylation	TAALNDRDQGGGSAG HHHCCCCCCCCCCCC	32.72	28450419
91	Ubiquitination	ALNDRDQGGGSAGHP HCCCCCCCCCCCCCC	60.80	21890473
95	Phosphorylation	RDQGGGSAGHPASRN CCCCCCCCCCCCHHC	12.05	23186163
95	Ubiquitination	RDQGGGSAGHPASRN CCCCCCCCCCCCHHC	12.05	22817900
108	Phosphorylation	RNKKILNKKKLKRKQ HCHHHCCHHHHHHHH	50.14	27080861
126	Ubiquitination	SKVKTRSKSENLENT HHCCCCCCCCCCCCC	45.22	-
127	Phosphorylation	KVKTRSKSENLENTV HCCCCCCCCCCCCCE	44.86	23186163
129	Phosphorylation	KTRSKSENLENTVII CCCCCCCCCCCCEEE	17.04	20068231
134	Phosphorylation	SENLENTVIIPDIKL CCCCCCCEEECCCCC	27.87	23898821
137	Phosphorylation	LENTVIIPDIKLHSN CCCCEEECCCCCCCC	25.85	21955146
140	Phosphorylation	TVIIPDIKLHSNPSA CEEECCCCCCCCCHH	42.23	21955146
143	Phosphorylation	IPDIKLHSNPSAFNI ECCCCCCCCCHHHHH	46.04	20164059
145	Phosphorylation	DIKLHSNPSAFNIYC CCCCCCCCHHHHHHC	57.09	20164059
151	Phosphorylation	NPSAFNIYCNVRHCV CCHHHHHHCCCEEHH	45.67	22115753
167	Phosphorylation	EWQKKEISLAAASKN HHHHHHHHHHHHHCC	3.26	20068231
178	Phosphorylation	ASKNSVQSGESDSDE HHCCCCCCCCCCCCC	11.68	18669648
181	Phosphorylation	NSVQSGESDSDEEEE CCCCCCCCCCCCCHH	28.00	24719451
183	Phosphorylation	VQSGESDSDEEEESK CCCCCCCCCCCHHHC	3.62	24719451
226	Phosphorylation	PSLCLRSLQALLNVL HHHHHHHHHHHHHHH	29.86	22210691
232	Phosphorylation	SLQALLNVLQGQQPE HHHHHHHHHCCCCCC	41.95	22210691
257	Phosphorylation	ESLFQLLLEITVRST HHHHHHHHHHHHHCC	25.27	-
262	Phosphorylation	LLLEITVRSTGMNDS HHHHHHHHCCCCCCC	16.57	-
351	Phosphorylation	GIKKAALMHKWPLKE CHHHHHHHCCCCCCC	37.72	29507054
354	Phosphorylation	KAALMHKWPLKEISV HHHHHCCCCCCCCCC	31.36	29507054
356	Phosphorylation	ALMHKWPLKEISVDE HHHCCCCCCCCCCCC	10.90	29507054
367	Methylation	SVDEDDQCLLQNDGF CCCCCCCEEECCCCE	31.79	115383785
376	Phosphorylation	LQNDGFFLYLLCKDG ECCCCEEEEEEECCC	38.30	-
380	Phosphorylation	GFFLYLLCKDGLYKI CEEEEEEECCCCEEC	8.12	17081983
384	Phosphorylation	YLLCKDGLYKIGSGY EEEECCCCEECCCCC	4.97	-
396	Phosphorylation	SGYSGTVRGHIYNST CCCCCCCHHCCCCCC	23.19	-
405	Methylation	HIYNSTSRIRNRKEK CCCCCCHHCCCCCCC	5.47	-
414	Phosphorylation	RNRKEKKSWLGYAQG CCCCCCCCHHHHCHH	24.88	-
418	Phosphorylation	EKKSWLGYAQGYLLY CCCCHHHHCHHEEEE	48.41	17081983
434	Phosphorylation	DVNNHSMTAIRISPE ECCCCCCEEEEECHH	2.75	-
539	Phosphorylation	AILGAGREFALMKTA HHHCCCHHEEEEEEC	24.43	20068231
540	Ubiquitination	ILGAGREFALMKTAN HHCCCHHEEEEEECC	66.53	-
562	Ubiquitination	KYQSLGIKQGGPSAG CCCCCCEECCCCCCC	46.53	-
568	Phosphorylation	IKQGGPSAGKWVELP EECCCCCCCCEEEEE	21.34	-
570	Phosphorylation	QGGPSAGKWVELPIT CCCCCCCCEEEEECC	26.72	-
572	Phosphorylation	GPSAGKWVELPITKS CCCCCCEEEEECCCC	42.78	-
578	Ubiquitination	WVELPITKSPKIVHF EEEEECCCCCCEEEE	68.50	-
579	Phosphorylation	VELPITKSPKIVHFS EEEECCCCCCEEEEE	46.82	-
580	Phosphorylation	ELPITKSPKIVHFSV EEECCCCCCEEEEEE	28.83	24275569
582	Phosphorylation	PITKSPKIVHFSVGH ECCCCCCEEEEEECC	32.55	21955146
630	Phosphorylation	QSKPYKPKKIIKMEG CCCCCCCCEEEEEEC	14.24	22210691
631	Phosphorylation	SKPYKPKKIIKMEGK CCCCCCCEEEEEECE	25.55	22210691
633	Phosphorylation	PYKPKKIIKMEGKIV CCCCCEEEEEECEEE	18.84	23403867
634	Phosphorylation	YKPKKIIKMEGKIVV CCCCEEEEEECEEEE	32.45	23403867
635	Phosphorylation	KPKKIIKMEGKIVVY CCCEEEEEECEEEEE	30.70	23403867
646	Ubiquitination	IVVYTACNNGSSSVI EEEEEEECCCCCCEE	19.18	23503661
666	Ubiquitination	LYMFGKDAIYSDSSS EEEECCCCEECCCCC	18.71	23503661
687	Ubiquitination	GHFVTQVAMGKAHTC CCCEEEEECCCCCEE	58.87	-
724	Ubiquitination	TGAMNQGGKGFGVEN CCCCCCCCCCCCHHH	47.12	-
760	Ubiquitination	MCPPGMHKWKLEQCM CCCCCCCCCCCCCCE	3.21	-
781	Ubiquitination	DCTGYGASCVSSGRP CCCCCCCHHHCCCCC	52.56	21890473
785	Ubiquitination	YGASCVSSGRPDRVP CCCHHHCCCCCCCCC	12.67	22817900
861	Phosphorylation	HLQLRQEEKRQRVIR HHHHCHHHHHHHHHH	38.11	23312004
886	Phosphorylation	LVFAGPIFMNHREQA EEEECCEECCHHHHH	34.42	18452278
924	Phosphorylation	ERGEKDASKITTYPP CCCCCCHHHCCCCCC	10.90	18452278
937	Ubiquitination	PPGSVRFDCELRAVQ CCCCEEEEEEEEEEE	38.47	21890473
941	Ubiquitination	VRFDCELRAVQVSCG EEEEEEEEEEEEECC	29.87	22817900
979	Phosphorylation	LGHGDVNSRGCPTLV CCCCCCCCCCCCCHH	23.35	24719451
1008	Ubiquitination	NHTAVLLMDGQVFTF CCEEEEEECCEEEEE	46.65	21890473
1008 (in isoform 1)	Ubiquitination	-	46.65	21890473
1008 (in isoform 2)	Ubiquitination	-	46.65	21890473
1010	Ubiquitination	TAVLLMDGQVFTFGS EEEEEECCEEEEEEC	28.48	21890473
1014	Ubiquitination	LMDGQVFTFGSFSKG EECCEEEEEECCCCC	22.20	22817900
1046	Ubiquitination	PMPNIGSKYGRKATW CCCCCCCCCCCEEEE	35.08	21890473
1050	Ubiquitination	IGSKYGRKATWIGAS CCCCCCCEEEEEECC	21.73	22817900
1123	Phosphorylation	NDSEQEDLQGFGVCL CHHCCHHHCCCCEEC	40.45	-
1127	Sulfoxidation	QEDLQGFGVCLDPVY CHHHCCCCEECCHHH	3.14	21406390
1135	Phosphorylation	VCLDPVYDVIWRFRP EECCHHHHHHHCCCC	18.04	27050516
1142	Phosphorylation	DVIWRFRPNTRELWC HHHHCCCCCCCCEEE	48.95	18691976
1148	Phosphorylation	RPNTRELWCYNAVVA CCCCCCEEEEEEEEE	21.12	22210691
1149	Phosphorylation	PNTRELWCYNAVVAD CCCCCEEEEEEEEEC	30.90	22210691
1151	Phosphorylation	TRELWCYNAVVADAR CCCEEEEEEEEECCC	18.52	22210691
1174	Ubiquitination	SRCSILSPELALPTG HHCCCCCHHHCCCCC	3.21	22817900
1176	Phosphorylation	CSILSPELALPTGSR CCCCCHHHCCCCCCC	33.67	25907765
1177	Phosphorylation	SILSPELALPTGSRA CCCCHHHCCCCCCCC	37.36	25907765
1177	Ubiquitination	SILSPELALPTGSRA CCCCHHHCCCCCCCC	37.36	21890473
1180	Phosphorylation	SPELALPTGSRALTT CHHHCCCCCCCCCCC	39.73	18691976
1181	Phosphorylation	PELALPTGSRALTTR HHHCCCCCCCCCCCH	25.71	25907765
1188	Phosphorylation	GSRALTTRSHAALHI CCCCCCCHHHHHHHH	14.43	25907765
1189	Phosphorylation	SRALTTRSHAALHIL CCCCCCHHHHHHHHH	32.34	25907765
1219	Phosphorylation	VASTEEETQAVMKVY CCCCHHHHHHHHHHH	18.52	30576142
1238	Phosphorylation	YSVVNRFESHGGGWG CCHHHCEECCCCCCC	18.15	22817900
1277	Phosphorylation	FGGRGEYTAKIKLFE CCCCCEEEEEEEEEE	8.58	-
1293	Phosphorylation	GPDGGDHETDGDLLA CCCCCCCCCCCCCCC	3.62	-
1330	Phosphorylation	VLLQAGWWYVAWARV CHHHCCEEEEEEEEE	38.98	-
1334	Phosphorylation	AGWWYVAWARVSGPS CCEEEEEEEEECCCC	38.61	-
1336	Ubiquitination	WWYVAWARVSGPSSD EEEEEEEEECCCCCC	5.48	23503661
1356	Ubiquitination	QASITTDDGVVFQFK CEEEECCCEEEEEEE	43.57	23503661
1395	Phosphorylation	TSDGSASKGKQQTSE CCCCCCCCCCCCCCC	14.49	-
1395	Ubiquitination	TSDGSASKGKQQTSE CCCCCCCCCCCCCCC	14.49	-
1443	Phosphorylation	LGVEELRGLKGFQFT HCHHHHCCCCCCEEE	18.66	-
1445	Phosphorylation	VEELRGLKGFQFTAT HHHHCCCCCCEEEEE	31.54	-
1465	Phosphorylation	RLRFVGTCCLRLLRV HHHHHHHHHHHHHHH	35.06	24260401
1472	Phosphorylation	CCLRLLRVYTCEIYP HHHHHHHHEECEEEE	35.46	28450419
1472 (in isoform 2)	Phosphorylation	-	35.46	21406692
1492	Ubiquitination	KAVVEETSKLAECIG CHHHHCHHHHHHHHH	40.12	23503661
1510	Phosphorylation	TLLRKILSEGVDHCM HHHHHHHHCCCCEEE	6.98	-
1512	Ubiquitination	LRKILSEGVDHCMVK HHHHHHCCCCEEEEE	5.12	23503661
1563 (in isoform 2)	Ubiquitination	-	45.90	-
1565	Ubiquitination	ALQWACLCDLLNCLD HHHHHHHHHHHHHHC	17.66	23503661
1583 (in isoform 2)	Ubiquitination	-	43.22	-
1585	Ubiquitination	ANFKTSSSRLLAAVM CCCCCHHHHHHHHHH	6.74	23503661
1586	Phosphorylation	NFKTSSSRLLAAVMS CCCCHHHHHHHHHHH	27.75	29255136
1587	Phosphorylation	FKTSSSRLLAAVMSA CCCHHHHHHHHHHHH	39.69	29255136
1591	Phosphorylation	SSRLLAAVMSALCHT HHHHHHHHHHHHHCC	34.91	29978859
1592	Phosphorylation	SRLLAAVMSALCHTS HHHHHHHHHHHHCCC	35.35	29978859
1601	Ubiquitination	ALCHTSVKLTSIFPI HHHCCCCCHHHCCCC	4.53	23503661
1604	Sulfoxidation	HTSVKLTSIFPIAYD CCCCCHHHCCCCCCC	3.33	31801345
1621	Ubiquitination	VLLRSIVKQVSTEND HHHHHHHHHHCCCCC	32.64	23503661
1624	Phosphorylation	RSIVKQVSTENDSTL HHHHHHHCCCCCCCH	4.48	24719451
1625	Phosphorylation	SIVKQVSTENDSTLV HHHHHHCCCCCCCHH	41.41	20068231
1672	Phosphorylation	MLVIVVLPVRNSLRR CCCEEEECCCCHHHH	34.98	24275569
1710	Phosphorylation	LTASALGSEVDGLNS HHHHHHCCCCCCHHH	1.92	-
1756	Phosphorylation	FSVDKPGIVVVGFSV EECCCCCEEEEEEEE	24.32	24732914
1757	Phosphorylation	SVDKPGIVVVGFSVY ECCCCCEEEEEEEEE	16.94	24732914
1762	Ubiquitination	GIVVVGFSVYGGGGI CEEEEEEEEECCCCC	59.15	-
1764	Phosphorylation	VVVGFSVYGGGGIHE EEEEEEEECCCCCCE	16.39	24732914
1765	Phosphorylation	VVGFSVYGGGGIHEY EEEEEEECCCCCCEE	19.13	24732914
1766	Phosphorylation	VGFSVYGGGGIHEYE EEEEEECCCCCCEEE	24.48	24732914
1767	Phosphorylation	GFSVYGGGGIHEYEL EEEEECCCCCCEEEE	27.65	24732914
1770	Phosphorylation	VYGGGGIHEYELEVL EECCCCCCEEEEEEE	29.16	24732914
1772	Phosphorylation	GGGGIHEYELEVLVD CCCCCCEEEEEEEEC	45.67	24732914
1790	Acetylation	HAGDSTHSHRWTSLE CCCCCCCCCCEEEEE	38.79	19608861
1791	Phosphorylation	AGDSTHSHRWTSLEL CCCCCCCCCEEEEEE	13.17	25884760
1819	Ubiquitination	IAEIRLDKVVPLKEN CEEEECCEEEECCCC	23.61	-
1824	Ubiquitination	LDKVVPLKENVKYAV CCEEEECCCCHHHEE	11.26	-
1828	Acetylation	VPLKENVKYAVRLRN EECCCCHHHEEEEEE	12.88	19608861
1829	Phosphorylation	PLKENVKYAVRLRNY ECCCCHHHEEEEEEC	44.57	-
1859	Phosphorylation	CPDGVTFTFSTCSLS CCCCCEEEEEECEEC	38.01	24719451
1864	Ubiquitination	TFTFSTCSLSSNGTN EEEEEECEECCCCCC	74.27	22817900
1867	Ubiquitination	FSTCSLSSNGTNQTR EEECEECCCCCCCCC	41.12	21890473
1876	Phosphorylation	GTNQTRGQIPQILYY CCCCCCCCCCEEEEE	17.21	-
1877	Phosphorylation	TNQTRGQIPQILYYR CCCCCCCCCEEEEEE	16.06	24719451
1883	Acetylation	QIPQILYYRSEFDGD CCCEEEEEECCCCCH	51.95	26822725
1898	Ubiquitination	LQSQLLSKANEEDKN HHHHHHHHCCHHCCC	32.93	-
1914	O-linked_Glycosylation	SRALSVVSTVVRASK HHHHHHHHHHHHHCH	1.27	30379171
1963	Phosphorylation	IGPVAAAIPKVAVEV HHHHHHHCHHHHHHH	28.14	24275569
1964	Phosphorylation	GPVAAAIPKVAVEVF HHHHHHCHHHHHHHH	41.34	24275569
2020	Ubiquitination	ACTTSSHYAVIESEH ECCCCCCEEEEECCC	29.20	22817900
2023	Ubiquitination	TSSHYAVIESEHPYK CCCCEEEEECCCCCC	33.04	21890473
2093	Ubiquitination	VHENLNSWIELKKFS HHHHHHHHEEEEECC	42.58	22817900
2094	Ubiquitination	HENLNSWIELKKFSG HHHHHHHEEEEECCC	56.94	21890473
2094 (in isoform 2)	Ubiquitination	-	56.94	21890473
2096	Ubiquitination	NLNSWIELKKFSGSS HHHHHEEEEECCCCC	25.41	21890473
2129	Ubiquitination	ETASDYVKDDKASFY EEHHHHCCCCCHHHC	17.94	22817900
2132	Ubiquitination	SDYVKDDKASFYGFK HHHCCCCCHHHCEEE	8.05	21890473
2175	Ubiquitination	VCAAALMKKDLALPI HHHHHHHHCCCCCCC	18.71	-
2248	Ubiquitination	DDFIACVPGSSGGRL HHEEEECCCCCCCHH	15.57	24816145
2253	Phosphorylation	CVPGSSGGRLARWLQ ECCCCCCCHHHHHCC	32.05	30257219
2276	Ubiquitination	KTSLILNKDDIRCGW CCEEEEECCCCCCCC	30.16	-
2281	Phosphorylation	LNKDDIRCGWPTTIT EECCCCCCCCCEEEE	31.72	23927012
2296	Phosphorylation	VQTKDQYGDVVHVPN EEEECCCCCEEECCC	12.34	25159151
2300	Phosphorylation	DQYGDVVHVPNMKVE CCCCCEEECCCCEEE	20.72	20068231
2303	Phosphorylation	GDVVHVPNMKVEVKA CCEEECCCCEEEEEE	22.96	20068231
2304	Phosphorylation	DVVHVPNMKVEVKAV CEEECCCCEEEEEEE	38.74	20068231
2306	Phosphorylation	VHVPNMKVEVKAVPV EECCCCEEEEEEEEC	29.15	20068231
2309	Phosphorylation	PNMKVEVKAVPVSQK CCCEEEEEEEECCHH	23.09	20068231
2309	Ubiquitination	PNMKVEVKAVPVSQK CCCEEEEEEEECCHH	23.09	-
2310	Phosphorylation	NMKVEVKAVPVSQKK CCEEEEEEEECCHHC	11.54	20068231
2315	Phosphorylation	VKAVPVSQKKMSLQQ EEEEECCHHCCCCCH	27.84	25159151
2319	Phosphorylation	PVSQKKMSLQQDQAK ECCHHCCCCCHHHCC	33.18	24719451
2321	Phosphorylation	SQKKMSLQQDQAKKP CHHCCCCCHHHCCCC	24.36	21712546
2334	Phosphorylation	KPQRIPGSPAVTAAS CCCCCCCCCCCCCCC	5.14	20068231
2338	Phosphorylation	IPGSPAVTAASSNTD CCCCCCCCCCCCCCC	1.67	-
2341	Phosphorylation	SPAVTAASSNTDMTY CCCCCCCCCCCCCCC	7.92	28152594
2342	Phosphorylation	PAVTAASSNTDMTYG CCCCCCCCCCCCCCC	53.32	-
2344	Phosphorylation	VTAASSNTDMTYGGL CCCCCCCCCCCCCCC	11.64	-
2345	Phosphorylation	TAASSNTDMTYGGLA CCCCCCCCCCCCCCC	37.45	24505115
2348	Phosphorylation	SSNTDMTYGGLASPK CCCCCCCCCCCCCCC	43.14	-
2353	Phosphorylation	MTYGGLASPKLDVSY CCCCCCCCCCCCCCC	26.96	21815630
2355	Phosphorylation	YGGLASPKLDVSYEP CCCCCCCCCCCCCCC	38.66	24505115
2359	Phosphorylation	ASPKLDVSYEPMIVK CCCCCCCCCCCCHHH	52.71	-
2405	Acetylation	SENMLIRVNNDGTYC CCCCEEEECCCCCEE	59.82	7407385
2409	Acetylation	LIRVNNDGTYCANWT EEEECCCCCEECCCC	67.51	7407395
2420	Acetylation	ANWTPGAIGLYTLHV CCCCCCCEEEEEEEE	56.15	7407405
2422	Acetylation	WTPGAIGLYTLHVTI CCCCCEEEEEEEEEE	62.83	19608861
2445	Phosphorylation	LEVKVKDPPKGMIPP CEEEECCCCCCCCCC	37.06	28348404
2448	Phosphorylation	KVKDPPKGMIPPGTQ EECCCCCCCCCCCCC	33.35	28348404
2460	Acetylation	GTQLVKPKSEPQPNK CCCCCCCCCCCCCCC	35.85	19608861
2517	Phosphorylation	DDGVWLRLNDETIKK CCCEEEEECHHHHHH	40.07	22985185
2555	Phosphorylation	LLVPVDESKTNTDDF CEEECCCCCCCHHHH	2.69	27251275
2556	Ubiquitination	LVPVDESKTNTDDFF EEECCCCCCCHHHHH	3.93	-
2629	Phosphorylation	KVKAVGEVTNSEGTW EEEEEEEEECCCCCE	15.09	21406692
2643	Phosphorylation	WVQLDQNSMVEFCES EEEECCCCCEEEEEC	29.78	25159151
2643 (in isoform 2)	Phosphorylation	-	29.78	21406692
2645	Phosphorylation	QLDQNSMVEFCESDE EECCCCCEEEEECCC	37.27	25159151
2645 (in isoform 2)	Phosphorylation	-	37.27	21406692
2649	Phosphorylation	NSMVEFCESDEGEAW CCCEEEEECCCCCHH	44.33	25159151
2652	Phosphorylation	VEFCESDEGEAWSLA EEEEECCCCCHHHHH	19.39	30266825
2661	Phosphorylation	EAWSLARDRGGNQYL CHHHHHHCCCCCCCC	19.78	20068231
2663	Phosphorylation	WSLARDRGGNQYLRH HHHHHCCCCCCCCCC	22.56	20068231
2669	Phosphorylation	RGGNQYLRHEDEQAL CCCCCCCCCHHHHHH	16.40	20068231
2674	Phosphorylation	YLRHEDEQALLDQNS CCCCHHHHHHHCCCC	35.90	20068231
2681	Phosphorylation	QALLDQNSQTPPPSP HHHHCCCCCCCCCCC	5.46	20068231
2682	Phosphorylation	ALLDQNSQTPPPSPF HHHCCCCCCCCCCCC	26.66	29083192
2683	Phosphorylation	LLDQNSQTPPPSPFS HHCCCCCCCCCCCCC	32.97	17081983
2684	Phosphorylation	LDQNSQTPPPSPFSV HCCCCCCCCCCCCCE	29.58	23312004
2685	Phosphorylation	DQNSQTPPPSPFSVQ CCCCCCCCCCCCCEE	42.63	23312004
2687	Phosphorylation	NSQTPPPSPFSVQAF CCCCCCCCCCCEEEE	33.13	17081983
2689	Phosphorylation	QTPPPSPFSVQAFNK CCCCCCCCCEEEECC	31.47	25159151
2690	Phosphorylation	TPPPSPFSVQAFNKG CCCCCCCCEEEECCC	43.54	18669648
2691	Phosphorylation	PPPSPFSVQAFNKGA CCCCCCCEEEECCCC	41.55	23312004
2694	Phosphorylation	SPFSVQAFNKGASCS CCCCEEEECCCCCCC	47.50	29083192
2697	Phosphorylation	SVQAFNKGASCSAQG CEEEECCCCCCCCCC	33.03	28348404
2698	Phosphorylation	VQAFNKGASCSAQGF EEEECCCCCCCCCCC	47.19	29083192
2699	Phosphorylation	QAFNKGASCSAQGFD EEECCCCCCCCCCCC	42.07	20068231
2701	Phosphorylation	FNKGASCSAQGFDYG ECCCCCCCCCCCCCC	27.57	28348404
2712	Phosphorylation	FDYGLGNSKGDRGNI CCCCCCCCCCCCCCC	27.10	-
2725	Phosphorylation	NISTSSKPASTSGKS CCCCCCCCCCCCCCC	27.71	28555341
2729	Phosphorylation	SSKPASTSGKSELSS CCCCCCCCCCCCCCC	25.09	23186163
2731	Phosphorylation	KPASTSGKSELSSKH CCCCCCCCCCCCCCC	20.43	23917254
2743	Phosphorylation	SKHSRSLKPDGRMSR CCCCCCCCCCCCCCC	54.63	20873877
2745	Phosphorylation	HSRSLKPDGRMSRTT CCCCCCCCCCCCCCC	25.30	20873877
2747	Phosphorylation	RSLKPDGRMSRTTAD CCCCCCCCCCCCCCC	27.76	23401153
2749	Phosphorylation	LKPDGRMSRTTADQK CCCCCCCCCCCCCCC	35.89	29255136
2749 (in isoform 2)	Phosphorylation	-	35.89	21406692
2751	Phosphorylation	PDGRMSRTTADQKKP CCCCCCCCCCCCCCC	25.54	29255136
2751 (in isoform 2)	Phosphorylation	-	25.54	21406692
2756	Phosphorylation	SRTTADQKKPRGTES CCCCCCCCCCCCCCC	16.82	29255136
2756 (in isoform 2)	Phosphorylation	-	16.82	21406692
2759	Phosphorylation	TADQKKPRGTESLSA CCCCCCCCCCCCCCH	38.99	29255136
2762	Phosphorylation	QKKPRGTESLSASES CCCCCCCCCCCHHHH	48.70	30576142
2768	Phosphorylation	TESLSASESLILKSD CCCCCHHHHEEECCC	31.44	23403867
2769	Phosphorylation	ESLSASESLILKSDA CCCCHHHHEEECCCH	20.27	23403867
2770	Phosphorylation	SLSASESLILKSDAA CCCHHHHEEECCCHH	39.59	23403867
2774	Phosphorylation	SESLILKSDAAKLRS HHHEEECCCHHHHCC	33.88	29255136
2779	Phosphorylation	LKSDAAKLRSDSHSR ECCCHHHHCCCCCCC	32.93	23403867
2782	Phosphorylation	DAAKLRSDSHSRSLS CHHHHCCCCCCCCCC	43.41	29396449
2783	Phosphorylation	AAKLRSDSHSRSLSP HHHHCCCCCCCCCCC	41.35	30576142
2785	Acetylation	KLRSDSHSRSLSPNH HHCCCCCCCCCCCCC	62.18	7825963
2787	Acetylation	RSDSHSRSLSPNHNT CCCCCCCCCCCCCCH	69.67	19819005
2787	Phosphorylation	RSDSHSRSLSPNHNT CCCCCCCCCCCCCCH	69.67	17081983
2788	Phosphorylation	SDSHSRSLSPNHNTL CCCCCCCCCCCCCHH	46.64	21712546
2789	Phosphorylation	DSHSRSLSPNHNTLQ CCCCCCCCCCCCHHH	4.75	17081983
2794	Phosphorylation	SLSPNHNTLQTLKSD CCCCCCCHHHHHHHC	46.54	25159151
2795	Phosphorylation	LSPNHNTLQTLKSDG CCCCCCHHHHHHHCC	21.61	25159151
2797	Phosphorylation	PNHNTLQTLKSDGRM CCCCHHHHHHHCCCC	49.27	28176443
2800	Phosphorylation	NTLQTLKSDGRMPSS CHHHHHHHCCCCCCC	44.38	25159151
2801	Phosphorylation	TLQTLKSDGRMPSSS HHHHHHHCCCCCCCC	24.65	26055452
2804	Phosphorylation	TLKSDGRMPSSSRAE HHHHCCCCCCCCCCC	38.25	23927012
2805	Phosphorylation	LKSDGRMPSSSRAES HHHCCCCCCCCCCCC	49.52	23927012
2806	Phosphorylation	KSDGRMPSSSRAESP HHCCCCCCCCCCCCC	27.74	23401153
2810	Acetylation	RMPSSSRAESPGPGS CCCCCCCCCCCCCCC	58.30	30590545
2812	Phosphorylation	PSSSRAESPGPGSRL CCCCCCCCCCCCCCC	6.15	24719451
2817	Phosphorylation	AESPGPGSRLSSPKP CCCCCCCCCCCCCCC	41.85	-
2820	Phosphorylation	PGPGSRLSSPKPKTL CCCCCCCCCCCCCCC	13.10	24719451
2821	Phosphorylation	GPGSRLSSPKPKTLP CCCCCCCCCCCCCCC	38.59	27251275
2822	Phosphorylation	PGSRLSSPKPKTLPA CCCCCCCCCCCCCCC	36.75	23911959
2826	Phosphorylation	LSSPKPKTLPANRSS CCCCCCCCCCCCCCC	40.04	24719451
2831	Phosphorylation	PKTLPANRSSPSGAS CCCCCCCCCCCCCCC	31.58	29255136
2831 (in isoform 2)	Phosphorylation	-	31.58	21406692
2832	Phosphorylation	KTLPANRSSPSGASS CCCCCCCCCCCCCCC	65.58	24719451
2833	Phosphorylation	TLPANRSSPSGASSP CCCCCCCCCCCCCCC	32.79	29255136
2833 (in isoform 2)	Phosphorylation	-	32.79	21406692
2835	Phosphorylation	PANRSSPSGASSPRS CCCCCCCCCCCCCCC	27.40	22167270
2836	Phosphorylation	ANRSSPSGASSPRSS CCCCCCCCCCCCCCC	19.13	22167270
2837	Phosphorylation	NRSSPSGASSPRSSS CCCCCCCCCCCCCCC	28.74	23927012
2839	Phosphorylation	SSPSGASSPRSSSPH CCCCCCCCCCCCCCC	31.09	24719451
2842	Phosphorylation	SGASSPRSSSPHDKN CCCCCCCCCCCCCCC	33.57	23927012
2844	Phosphorylation	ASSPRSSSPHDKNLP CCCCCCCCCCCCCCC	51.33	33259812
2851	Phosphorylation	SPHDKNLPQKSTAPV CCCCCCCCCCCCCCC	29.68	24719451
2858	Phosphorylation	PQKSTAPVKTKLDPP CCCCCCCCCCCCCCC	35.74	23403867
2859	Phosphorylation	QKSTAPVKTKLDPPR CCCCCCCCCCCCCCC	47.92	23403867
2860	Phosphorylation	KSTAPVKTKLDPPRE CCCCCCCCCCCCCCC	31.97	23403867
2865	Phosphorylation	VKTKLDPPRERSKSD CCCCCCCCCCCCCCC	52.78	20860994
2869	Phosphorylation	LDPPRERSKSDSYTL CCCCCCCCCCCCCCC	51.18	17081983
2870	Phosphorylation	DPPRERSKSDSYTLD CCCCCCCCCCCCCCC	39.99	27251275
2871	Phosphorylation	PPRERSKSDSYTLDP CCCCCCCCCCCCCCH	51.10	29255136
2873	Phosphorylation	RERSKSDSYTLDPDT CCCCCCCCCCCCHHH	31.11	29255136
2875	Phosphorylation	RSKSDSYTLDPDTLR CCCCCCCCCCHHHHH	52.09	-
2876	Phosphorylation	SKSDSYTLDPDTLRK CCCCCCCCCHHHHHC	34.77	29255136
2882	Phosphorylation	TLDPDTLRKKKMPLT CCCHHHHHCCCCCCC	27.01	30266825
2889	Phosphorylation	RKKKMPLTEPLRGRS HCCCCCCCCCCCCCC	26.43	24719451
2892	Phosphorylation	KMPLTEPLRGRSTSP CCCCCCCCCCCCCCC	34.94	30266825
2896	Phosphorylation	TEPLRGRSTSPKPKS CCCCCCCCCCCCCCC	36.73	-
2897	Phosphorylation	EPLRGRSTSPKPKSV CCCCCCCCCCCCCCC	2.66	24719451
2903	Phosphorylation	STSPKPKSVPKDSTD CCCCCCCCCCCCCCC	7.51	-
2905	Phosphorylation	SPKPKSVPKDSTDSP CCCCCCCCCCCCCCC	32.90	28450419
2907	Phosphorylation	KPKSVPKDSTDSPGS CCCCCCCCCCCCCCC	37.57	28450419
2909	Phosphorylation	KSVPKDSTDSPGSEN CCCCCCCCCCCCCCC	27.94	28450419
2911	Phosphorylation	VPKDSTDSPGSENRA CCCCCCCCCCCCCCC	26.21	21815630
2912	Phosphorylation	PKDSTDSPGSENRAP CCCCCCCCCCCCCCC	23.82	21815630
2916	Phosphorylation	TDSPGSENRAPSPHV CCCCCCCCCCCCCCH	20.65	28450419
2917	Phosphorylation	DSPGSENRAPSPHVV CCCCCCCCCCCCCHH	54.79	28450419
2920	Phosphorylation	GSENRAPSPHVVQEN CCCCCCCCCCHHCCC	45.58	24719451
2932	Phosphorylation	QENLHSEVVEVCTSS CCCCCHHHHHHHCCC	18.63	29396449
2938	Ubiquitination	EVVEVCTSSTLKTNS HHHHHHCCCCCCCCC	15.14	24816145
2945	Phosphorylation	SSTLKTNSLTDSTCD CCCCCCCCCCCCCCC	31.03	-
2947	Phosphorylation	TLKTNSLTDSTCDDS CCCCCCCCCCCCCCC	19.16	23401153
2952	Ubiquitination	SLTDSTCDDSSEFKS CCCCCCCCCCCCCEE	41.36	23000965
2966	Phosphorylation	SVDEGSNKVHFSIGK ECCCCCCCEEEEEEC	27.67	28555341
2967	Phosphorylation	VDEGSNKVHFSIGKA CCCCCCCEEEEEECC	36.72	29970186
2970	Phosphorylation	GSNKVHFSIGKAPLK CCCCEEEEEECCCCC	8.61	-
2975	Phosphorylation	HFSIGKAPLKDEQEM EEEEECCCCCCHHHH	35.52	24719451
2985	Phosphorylation	DEQEMRASPKISRKC CHHHHHCCHHHHHHH	5.84	24719451
3003	Ubiquitination	HTRPKKEKSSFLFKG CCCCCCCCCCCCCCC	26.08	-
3009	Ubiquitination	EKSSFLFKGDGSKPL CCCCCCCCCCCCCCC	27.43	24816145
3015	Phosphorylation	FKGDGSKPLEPAKQA CCCCCCCCCHHHHHH	34.19	24719451
3025	Ubiquitination	PAKQAMSPSVAECAR HHHHHCCHHHHHHHH	67.17	24816145
3033	Phosphorylation	SVAECARAVFASFLW HHHHHHHHHHHHHHC	23.01	28555341
3037	Ubiquitination	CARAVFASFLWHEGI HHHHHHHHHHCCCCC	52.80	27667366
3040	Phosphorylation	AVFASFLWHEGIVHD HHHHHHHCCCCCHHH	53.06	-
3043	Ubiquitination	ASFLWHEGIVHDAMA HHHHCCCCCHHHHHH	65.53	24816145
3048	Ubiquitination	HEGIVHDAMACSSFL CCCCHHHHHHHHHHH	54.19	24816145
3052	Phosphorylation	VHDAMACSSFLKFHP HHHHHHHHHHHHHCH	25.18	22617229
3056	Phosphorylation	MACSSFLKFHPELSK HHHHHHHHHCHHHCH	10.53	20068231
3057	Phosphorylation	ACSSFLKFHPELSKE HHHHHHHHCHHHCHH	42.30	20068231
3061	Ubiquitination	FLKFHPELSKEHAPI HHHHCHHHCHHCCCH	2.57	24816145
3063	Ubiquitination	KFHPELSKEHAPIRS HHCHHHCHHCCCHHH	20.81	-
3065	Ubiquitination	HPELSKEHAPIRSSL CHHHCHHCCCHHHHC	7.37	24816145
3069	Ubiquitination	SKEHAPIRSSLNSQQ CHHCCCHHHHCCCCC	32.50	24816145
3072	Phosphorylation	HAPIRSSLNSQQPTE CCCHHHHCCCCCCCH	24.78	23090842
3073	Ubiquitination	APIRSSLNSQQPTEE CCHHHHCCCCCCCHH	47.84	24816145
3076	Phosphorylation	RSSLNSQQPTEEKET HHHCCCCCCCHHHHH	21.35	20068231
3084	Phosphorylation	PTEEKETKLKNRHSL CCHHHHHHHCCCHHH	25.67	-
3084	Ubiquitination	PTEEKETKLKNRHSL CCHHHHHHHCCCHHH	25.67	24816145
3090	Phosphorylation	TKLKNRHSLEISSAL HHHCCCHHHHHHHHH	47.65	24719451
3091	Ubiquitination	KLKNRHSLEISSALN HHCCCHHHHHHHHHH	13.75	23503661
3094	Phosphorylation	NRHSLEISSALNMFN CCHHHHHHHHHHHHC	31.98	20068231
3094	Ubiquitination	NRHSLEISSALNMFN CCHHHHHHHHHHHHC	31.98	24816145
3095	Phosphorylation	RHSLEISSALNMFNI CHHHHHHHHHHHHCC	5.40	20068231
3095	Ubiquitination	RHSLEISSALNMFNI CHHHHHHHHHHHHCC	5.40	24816145
3100	Phosphorylation	ISSALNMFNIAPHGP HHHHHHHHCCCCCCC	44.06	29888752
3102	Phosphorylation	SALNMFNIAPHGPDI HHHHHHCCCCCCCCH	41.85	29888752
3103	Phosphorylation	ALNMFNIAPHGPDIS HHHHHCCCCCCCCHH	16.03	29888752
3103	Ubiquitination	ALNMFNIAPHGPDIS HHHHHCCCCCCCCHH	16.03	24816145
3107	Phosphorylation	FNIAPHGPDISKMGS HCCCCCCCCHHHCCC	15.08	29888752
3109	Ubiquitination	IAPHGPDISKMGSIN CCCCCCCHHHCCCCC	21.21	24816145
3111	Phosphorylation	PHGPDISKMGSINKN CCCCCHHHCCCCCHH	15.99	29888752
3114	Phosphorylation	PDISKMGSINKNKVL CCHHHCCCCCHHHHH	27.78	29888752
3125	Ubiquitination	NKVLSMLKEPPLHEK HHHHHHHCCCCCCCC	1.59	24816145
3136	Ubiquitination	LHEKCEDGKTETTFE CCCCCCCCCCEEEEE	28.44	24816145
3141	Phosphorylation	EDGKTETTFEMSMHN CCCCCEEEEEEHHHH	27.26	22210691
3142	Ubiquitination	DGKTETTFEMSMHNT CCCCEEEEEEHHHHC	38.49	24816145
3143	Ubiquitination	GKTETTFEMSMHNTM CCCEEEEEEHHHHCC	24.03	24816145
3148	Phosphorylation	TFEMSMHNTMKSKSP EEEEHHHHCCCCCCC	31.01	25159151
3151	Phosphorylation	MSMHNTMKSKSPLPL EHHHHCCCCCCCCCC	11.42	25159151
3159	Ubiquitination	SKSPLPLTLQHLVAF CCCCCCCHHHHHHHH	57.71	24816145
3161	Ubiquitination	SPLPLTLQHLVAFWE CCCCCHHHHHHHHHH	65.58	24816145
3167	Phosphorylation	LQHLVAFWEDISLAT HHHHHHHHHHCHHHH	51.04	26657352
3167	Ubiquitination	LQHLVAFWEDISLAT HHHHHHHHHHCHHHH	51.04	24816145
3169	Ubiquitination	HLVAFWEDISLATIK HHHHHHHHCHHHHHH	80.16	24816145
3176	Methylation	DISLATIKAASQNMI HCHHHHHHHHHCCCC	59.74	-
3178	Ubiquitination	SLATIKAASQNMIFP HHHHHHHHHCCCCCC	50.56	24816145
3184	Ubiquitination	AASQNMIFPSPGSCA HHHCCCCCCCCCCCH	33.21	24816145
3186	Phosphorylation	SQNMIFPSPGSCAVL HCCCCCCCCCCCHHH	10.12	-
3189	Phosphorylation	MIFPSPGSCAVLKKK CCCCCCCCCHHHCHH	2.70	27251275
3195	Ubiquitination	GSCAVLKKKECEKEN CCCHHHCHHHHHHHC	40.09	24816145
3201	Phosphorylation	KKKECEKENKKSKKE CHHHHHHHCHHCHHH	38.30	22210691
3203	Ubiquitination	KECEKENKKSKKEKK HHHHHHCHHCHHHHH	3.38	24816145
3215	Phosphorylation	EKKKKEKAEVRPRGN HHHHHHHHCCCCCCC	11.82	22210691
3228	Phosphorylation	GNLFGEMAQLAVGGP CCHHHHHHHHHCCCC	8.55	22817900
3234	Phosphorylation	MAQLAVGGPEKDTIC HHHHHCCCCCCCCCH	9.61	22817900
3236	Phosphorylation	QLAVGGPEKDTICEL HHHCCCCCCCCCHHH	22.82	22817900
3256	Phosphorylation	PYPVTYHMRQAHPGC CCCCEEEECCCCCCC	15.56	22817900
3266	Phosphorylation	AHPGCGRYAGGQGYN CCCCCCCCCCCCCCC	44.32	-
3272	Phosphorylation	RYAGGQGYNSIGHFC CCCCCCCCCCCCCCC	47.10	-
3274	Phosphorylation	AGGQGYNSIGHFCGG CCCCCCCCCCCCCCC	31.32	-
3294	Phosphorylation	GDGGIGGSTWYLVCD CCCCCCHHHEEEEEH	17.52	-
3339	Phosphorylation	PRALPTMEAHQVIKA CCCCCCCCHHHHHHH	55.18	25159151
3356	Phosphorylation	LFLLSLSSAAEPSIL HHHHCCCCCCCCEEE	11.95	-
3377	Phosphorylation	PFQSQLPSVKEGISE CHHHCCCCCCCCCCC	12.33	27251275
3382	Methylation	LPSVKEGISEDLPVK CCCCCCCCCCCCCCC	25.86	115383777
3383	Phosphorylation	PSVKEGISEDLPVKM CCCCCCCCCCCCCCH	12.73	22468782
3386	Phosphorylation	KEGISEDLPVKMPCL CCCCCCCCCCCHHHH	23.57	28102081
3387	Phosphorylation	EGISEDLPVKMPCLY CCCCCCCCCCHHHHH	27.58	28450419
3388	Phosphorylation	GISEDLPVKMPCLYL CCCCCCCCCHHHHHH	27.61	22499768
3393	Phosphorylation	LPVKMPCLYLQTLAR CCCCHHHHHHHHHHH	14.13	28450419
3395	Phosphorylation	VKMPCLYLQTLARHH CCHHHHHHHHHHHHC	17.69	28450419
3397	Phosphorylation	MPCLYLQTLARHHHE HHHHHHHHHHHHCHH	14.52	26074081
3401	Phosphorylation	YLQTLARHHHENFVG HHHHHHHHCHHCCCC	25.12	26074081
3414	Phosphorylation	VGYQDDNLFQDEMRY CCCCCCCCCHHHHHH	26.25	26074081
3418	Phosphorylation	DDNLFQDEMRYLRST CCCCCHHHHHHHHCC	32.73	25159151
3420	Methylation	NLFQDEMRYLRSTSV CCCHHHHHHHHCCCC	52.13	-
3421	Phosphorylation	LFQDEMRYLRSTSVP CCHHHHHHHHCCCCC	45.13	25159151
3422	Phosphorylation	FQDEMRYLRSTSVPA CHHHHHHHHCCCCCC	12.62	25159151
3424	Phosphorylation	DEMRYLRSTSVPAPY HHHHHHHCCCCCCCE	5.65	18669648
3425	Phosphorylation	EMRYLRSTSVPAPYI HHHHHHCCCCCCCEE	35.91	28450419
3426	Phosphorylation	MRYLRSTSVPAPYIS HHHHHCCCCCCCEEE	38.65	24719451
3427	Phosphorylation	RYLRSTSVPAPYISV HHHHCCCCCCCEEEC	25.02	26074081
3438	Phosphorylation	YISVTPDASPNVFEE EEECCCCCCCCCCCC	15.81	23927012
3439	Phosphorylation	ISVTPDASPNVFEEP EECCCCCCCCCCCCC	13.99	23403867
3440	Phosphorylation	SVTPDASPNVFEEPE ECCCCCCCCCCCCCC	16.03	25159151
3444	Phosphorylation	DASPNVFEEPESNMK CCCCCCCCCCCHHCC	25.69	23403867
3446	Phosphorylation	SPNVFEEPESNMKSM CCCCCCCCCHHCCCC	26.41	23927012
3451	Phosphorylation	EEPESNMKSMPPSLE CCCCHHCCCCCCCCC	24.27	23927012
3456	Phosphorylation	NMKSMPPSLETSPIT HCCCCCCCCCCCCCC	28.64	27251275
3459	Phosphorylation	SMPPSLETSPITDTD CCCCCCCCCCCCCHH	17.73	19413330
3460	Phosphorylation	MPPSLETSPITDTDL CCCCCCCCCCCCHHH	1.95	19413330
3467	Phosphorylation	SPITDTDLAKRTVFQ CCCCCHHHHHHHHHH	34.88	19664994
3470	Phosphorylation	TDTDLAKRTVFQRSY CCHHHHHHHHHHCCC	35.77	30266825
3474	Phosphorylation	LAKRTVFQRSYSVVA HHHHHHHHCCCEEEC	24.00	23403867
3475	Phosphorylation	AKRTVFQRSYSVVAS HHHHHHHCCCEEECC	26.03	23403867
3476	Phosphorylation	KRTVFQRSYSVVASE HHHHHHCCCEEECCH	5.37	-
3478	Phosphorylation	TVFQRSYSVVASEYD HHHHCCCEEECCHHH	44.99	18669648
3481	Phosphorylation	QRSYSVVASEYDKQH HCCCEEECCHHHHCC	25.53	21712546
3485	Phosphorylation	SVVASEYDKQHSILP EEECCHHHHCCCCCH	24.31	27732954
3489	Phosphorylation	SEYDKQHSILPARVK CHHHHCCCCCHHHEE	25.23	28555341
3496	Ubiquitination	SILPARVKAIPRRRV CCCHHHEEECCCCCC	70.82	-
3505	Phosphorylation	IPRRRVNSGDTEVGS CCCCCCCCCCCCHHH	5.70	19664994
3508	Phosphorylation	RRVNSGDTEVGSSLL CCCCCCCCCHHHHHH	4.32	17081983
3519	Phosphorylation	SSLLRHPSPELSRLI HHHHCCCCHHHHHHH	39.29	-
3534	Ubiquitination	SAHSSLSKGERNFQW HHHHCCCCCCCCCCC	2.50	-
3621	Phosphorylation	EENKTSKENSEQEKD CCCCCCCCCHHHHHH	23.55	26503514
3623	Phosphorylation	NKTSKENSEQEKDTR CCCCCCCHHHHHHHC	28.25	26503514
3628	Phosphorylation	ENSEQEKDTRVCEHP CCHHHHHHHCCCCCC	24.14	26503514
3642	Ubiquitination	PLSDIVIAGEAAHPL CHHHEEEECCCCCCC	2.77	23000965
3713	Ubiquitination	LSKSDDGDSEESFSI HHCCCCCCCCCCEEE	21.24	23000965
3723	Phosphorylation	ESFSISIQSGFEAMS CCEEEEEHHCHHHHC	39.76	30576142
3726	Phosphorylation	SISIQSGFEAMSQEL EEEEHHCHHHHCHHH	26.36	30576142
3727	Ubiquitination	ISIQSGFEAMSQELC EEEHHCHHHHCHHHH	44.57	27667366
3729	Ubiquitination	IQSGFEAMSQELCIV EHHCHHHHCHHHHHH	33.85	23000965
3733	Phosphorylation	FEAMSQELCIVMCLK HHHHCHHHHHHHHHC	41.98	30576142
3747	Ubiquitination	KDLTSIVDIKTSSRP CCCHHCEECCCCCCC	18.84	23000965
3749	Ubiquitination	LTSIVDIKTSSRPAM CHHCEECCCCCCCCE	5.71	-
3750	Ubiquitination	TSIVDIKTSSRPAMI HHCEECCCCCCCCEE	57.16	-
3752	Ubiquitination	IVDIKTSSRPAMIGS CEECCCCCCCCEEEE	2.78	23000965
3756	Phosphorylation	KTSSRPAMIGSLTDG CCCCCCCEEEECCCC	8.48	23312004
3758	Phosphorylation	SSRPAMIGSLTDGST CCCCCEEEECCCCCC	9.51	22817900
3765	Ubiquitination	GSLTDGSTETFWESG EECCCCCCCCCCCCC	49.80	23000965
3769	Ubiquitination	DGSTETFWESGDEDK CCCCCCCCCCCCCCC	42.81	23000965
3773	Phosphorylation	ETFWESGDEDKNKTK CCCCCCCCCCCCCCC	20.86	-
3773	Ubiquitination	ETFWESGDEDKNKTK CCCCCCCCCCCCCCC	20.86	23000965
3775	Phosphorylation	FWESGDEDKNKTKNI CCCCCCCCCCCCCCE	18.43	21060948
3777	Ubiquitination	ESGDEDKNKTKNITI CCCCCCCCCCCCEEE	4.54	23000965
3781	Ubiquitination	EDKNKTKNITINCVK CCCCCCCCEEEEECC	15.98	23503661
3788	Ubiquitination	NITINCVKGINARYV CEEEEECCCCCCEEE	3.41	23000965
3796	Phosphorylation	GINARYVSVHVDNSR CCCCEEEEEEEECCC	25.72	-
3798	Ubiquitination	NARYVSVHVDNSRDL CCEEEEEEEECCCCC	4.52	23000965
3799	Ubiquitination	ARYVSVHVDNSRDLG CEEEEEEEECCCCCC	13.48	23000965
3807	Ubiquitination	DNSRDLGNKVTSMTF ECCCCCCCCCEEEEE	69.57	23000965
3813	Phosphorylation	GNKVTSMTFLTGKAV CCCCEEEEECCCHHH	2.60	-
3813	Ubiquitination	GNKVTSMTFLTGKAV CCCCEEEEECCCHHH	2.60	23000965
3814	Ubiquitination	NKVTSMTFLTGKAVE CCCEEEEECCCHHHH	29.53	27667366
3827	Ubiquitination	VEDLCRIKQVDLDSR HHHHHCCEECCCCCC	29.19	-
3829	Ubiquitination	DLCRIKQVDLDSRHI HHHCCEECCCCCCCE	3.03	23000965
3832	Ubiquitination	RIKQVDLDSRHIGWV CCEECCCCCCCEEEE	5.85	27667366
3835	Ubiquitination	QVDLDSRHIGWVTSE ECCCCCCCEEEEEEE	54.80	-
3837	Ubiquitination	DLDSRHIGWVTSELP CCCCCCEEEEEEECC	27.33	27667366
3839	Phosphorylation	DSRHIGWVTSELPGG CCCCEEEEEEECCCC	40.30	21406692
3839 (in isoform 2)	Phosphorylation	-	40.30	21406692
3840	Phosphorylation	SRHIGWVTSELPGGD CCCEEEEEEECCCCC	23.36	21406692
3840	Ubiquitination	SRHIGWVTSELPGGD CCCEEEEEEECCCCC	23.36	23000965
3846	Ubiquitination	VTSELPGGDNHIIKI EEEECCCCCCEEEEE	3.48	23000965
3847	Ubiquitination	TSELPGGDNHIIKIE EEECCCCCCEEEEEE	13.45	23000965
3850	Ubiquitination	LPGGDNHIIKIELKG CCCCCCEEEEEEEEC	5.80	27667366
3852	Ubiquitination	GGDNHIIKIELKGPE CCCCEEEEEEEECCC	40.38	23503661
3854	Ubiquitination	DNHIIKIELKGPENT CCEEEEEEEECCCCE	37.37	27667366
3858	Ubiquitination	IKIELKGPENTLRVR EEEEEECCCCEEEEE	19.78	27667366
3862	Ubiquitination	LKGPENTLRVRQVKV EECCCCEEEEEEEEE	32.71	27667366
3863	Ubiquitination	KGPENTLRVRQVKVL ECCCCEEEEEEEEEE	3.54	23000965
3865	Ubiquitination	PENTLRVRQVKVLGW CCCEEEEEEEEEECC	23.48	23000965
3868	Ubiquitination	TLRVRQVKVLGWKDG EEEEEEEEEECCCCC	20.07	23503661
3871	Ubiquitination	VRQVKVLGWKDGEST EEEEEEECCCCCCCC	7.37	23000965
3873	Ubiquitination	QVKVLGWKDGESTKI EEEEECCCCCCCCEE	25.63	23000965
3882	Ubiquitination	GESTKIAGQISASVA CCCCEEEEEHHHHHH	55.78	23000965
3883	Phosphorylation	ESTKIAGQISASVAQ CCCEEEEEHHHHHHH	30.84	25159151
3883	Ubiquitination	ESTKIAGQISASVAQ CCCEEEEEHHHHHHH	30.84	27667366
3884	Ubiquitination	STKIAGQISASVAQQ CCEEEEEHHHHHHHH	52.57	27667366
3886	Ubiquitination	KIAGQISASVAQQRN EEEEEHHHHHHHHCC	66.41	23503661
3888	Ubiquitination	AGQISASVAQQRNCE EEEHHHHHHHHCCCH	43.24	23000965
3889	Ubiquitination	GQISASVAQQRNCEA EEHHHHHHHHCCCHH	43.51	2190698
3889 (in isoform 2)	Ubiquitination	-	43.51	21890473
3890 (in isoform 1)	Ubiquitination	-	19.60	21890473
3891	Ubiquitination	ISASVAQQRNCEAET HHHHHHHHCCCHHHH	7.64	23503661
3892	Ubiquitination	SASVAQQRNCEAETL HHHHHHHCCCHHHHH	5.94	27667366
3893	Phosphorylation	ASVAQQRNCEAETLR HHHHHHCCCHHHHHH	44.70	30266825
3893 (in isoform 2)	Phosphorylation	-	44.70	25849741
3894	Phosphorylation	SVAQQRNCEAETLRV HHHHHCCCHHHHHHH	27.26	29255136
3894 (in isoform 2)	Phosphorylation	-	27.26	25849741
3898	Ubiquitination	QRNCEAETLRVFRLI HCCCHHHHHHHHHHH	53.64	27667366
3899	Ubiquitination	RNCEAETLRVFRLIT CCCHHHHHHHHHHHH	59.69	23000965
3904	Ubiquitination	ETLRVFRLITSQVFG HHHHHHHHHHHHHHH	7.27	23503661
3905	Phosphorylation	TLRVFRLITSQVFGK HHHHHHHHHHHHHHH	24.41	25627689
3906	Phosphorylation	LRVFRLITSQVFGKL HHHHHHHHHHHHHHH	28.52	24247654
3907	Ubiquitination	RVFRLITSQVFGKLI HHHHHHHHHHHHHHH	39.48	23000965
3908	Ubiquitination	VFRLITSQVFGKLIS HHHHHHHHHHHHHHC	24.65	23503661
3912	Ubiquitination	ITSQVFGKLISGDAE HHHHHHHHHHCCCCC	44.50	23503661
3914	Ubiquitination	SQVFGKLISGDAEPT HHHHHHHHCCCCCCC	2.87	27667366
3916	Ubiquitination	VFGKLISGDAEPTPE HHHHHHCCCCCCCHH	10.33	23503661
3921	Phosphorylation	ISGDAEPTPEQEEKA HCCCCCCCHHHHHHH	27.36	-
3925	Ubiquitination	AEPTPEQEEKALLSS CCCCHHHHHHHHHCC	37.30	27667366
3927	Ubiquitination	PTPEQEEKALLSSPE CCHHHHHHHHHCCCC	5.92	23503661
3931	Phosphorylation	QEEKALLSSPEGEEK HHHHHHHCCCCCCHH	3.92	20068231
3931	Ubiquitination	QEEKALLSSPEGEEK HHHHHHHCCCCCCHH	3.92	27667366
3932	Phosphorylation	EEKALLSSPEGEEKV HHHHHHCCCCCCHHH	1.80	17081983
3932	Ubiquitination	EEKALLSSPEGEEKV HHHHHHCCCCCCHHH	1.80	27667366
3937	Ubiquitination	LSSPEGEEKVYNATS HCCCCCCHHHCCCCC	30.39	23503661
3938	Ubiquitination	SSPEGEEKVYNATSD CCCCCCHHHCCCCCC	4.77	23503661
3946	Ubiquitination	VYNATSDADLKEHMV HCCCCCCHHHHHHHH	8.63	23503661
3948	Ubiquitination	NATSDADLKEHMVGI CCCCCHHHHHHHHHH	65.68	27667366
3950	Ubiquitination	TSDADLKEHMVGIIF CCCHHHHHHHHHHEE	9.64	27667366
3952	Ubiquitination	DADLKEHMVGIIFSR CHHHHHHHHHHEEEH	29.45	23503661
3956	Ubiquitination	KEHMVGIIFSRSKLT HHHHHHHEEEHHHCH	37.56	27667366
3958	Ubiquitination	HMVGIIFSRSKLTNL HHHHHEEEHHHCHHH	64.62	27667366
3967	Ubiquitination	SKLTNLQKQVCAHIV HHCHHHHHHHHHHHH	63.22	27667366
3968	Ubiquitination	KLTNLQKQVCAHIVQ HCHHHHHHHHHHHHH	55.39	23503661
3973	Ubiquitination	QKQVCAHIVQAIRME HHHHHHHHHHHHHHH	12.63	27667366
3979	Ubiquitination	HIVQAIRMEATRVRE HHHHHHHHHHHHHHH	2.15	23503661
3984	Ubiquitination	IRMEATRVREEWEHA HHHHHHHHHHHHHHH	6.56	27667366
3985	Ubiquitination	RMEATRVREEWEHAI HHHHHHHHHHHHHHH	5.35	23503661
3986	Ubiquitination	MEATRVREEWEHAIS HHHHHHHHHHHHHHH	34.27	23503661
3992	Ubiquitination	REEWEHAISSKENAN HHHHHHHHHCCCCCC	20.07	27667366
4002	Ubiquitination	KENANSQPNDEDASS CCCCCCCCCCCCCCC	2.91	23503661
4004	Ubiquitination	NANSQPNDEDASSDA CCCCCCCCCCCCCHH	50.04	23503661
4010	Ubiquitination	NDEDASSDAYCFELL CCCCCCCHHHHHHHH	25.36	23503661
4012	Ubiquitination	EDASSDAYCFELLSM CCCCCHHHHHHHHHH	13.54	23503661
4021	Ubiquitination	FELLSMVLALSGSNV HHHHHHHHHHCCCCH	12.81	23503661
4022	Phosphorylation	ELLSMVLALSGSNVG HHHHHHHHHCCCCHH	26.92	24719451
4027	Ubiquitination	VLALSGSNVGRQYLA HHHHCCCCHHHHHHH	9.39	23503661
4032	Phosphorylation	GSNVGRQYLAQQLTL CCCHHHHHHHHHHHH	17.55	-
4038	Ubiquitination	QYLAQQLTLLQDLFS HHHHHHHHHHHHHHH	21.23	23503661
4046	Ubiquitination	LLQDLFSLLHTASPR HHHHHHHHHHHCCHH	29.17	23503661
4088	Phosphorylation	KSLPPADISDIIHST CCCCCCCHHHHHHCC	17.83	-
4089	Phosphorylation	SLPPADISDIIHSTE CCCCCCHHHHHHCCC	25.80	23403867
4093	Phosphorylation	ADISDIIHSTEKGDW CCHHHHHHCCCCCCH	17.17	-
4097	Phosphorylation	DIIHSTEKGDWNKLG HHHHCCCCCCHHHHH	26.75	23403867
4103	Phosphorylation	EKGDWNKLGILDMFL CCCCHHHHHHHHHHH	24.98	-
4113	Phosphorylation	LDMFLGCIAKALTVQ HHHHHHHHHHHHHHE	15.04	-
4114	Phosphorylation	DMFLGCIAKALTVQL HHHHHHHHHHHHHEE	29.32	-
4115	Phosphorylation	MFLGCIAKALTVQLK HHHHHHHHHHHHEEE	12.21	-
4124	Ubiquitination	LTVQLKAKGTTITGT HHHEEEECCCEEEEC	3.53	-
4157	Phosphorylation	NSSYLRRGESHWWMK CCCHHCCCCCCCCCC	19.92	24719451
4169	Phosphorylation	WMKGSTPTQISEIII CCCCCCCCHHHHHHH	21.23	24719451
4177	Phosphorylation	QISEIIIKLIKDMAA HHHHHHHHHHHHHHH	32.82	-
4184	Phosphorylation	KLIKDMAAGHLSEAW HHHHHHHHCCHHHHH	7.79	22210691
4185	Phosphorylation	LIKDMAAGHLSEAWS HHHHHHHCCHHHHHH	18.10	24719451
4195	Phosphorylation	SEAWSRVTKNAIAET HHHHHHHHHHHHHHH	2.37	24719451
4207	Phosphorylation	AETIIALTKMEEEFR HHHHHHHHHCHHHHC	36.65	24719451
4283	Phosphorylation	NVCGNLCTDCDRFLH CCHHHHCCCHHHHHH	19.86	20068231
4294	Phosphorylation	RFLHLHRRTKTHQRQ HHHHHHHHCHHHHHH	25.15	20068231
4296	Phosphorylation	LHLHRRTKTHQRQVF HHHHHHCHHHHHHHH	28.05	20068231
4298	Acetylation	LHRRTKTHQRQVFKE HHHHCHHHHHHHHHH	38.26	7681147
4304	Ubiquitination	THQRQVFKEEEEAIK HHHHHHHHHHHHHHC	22.68	-
4309	Acetylation	VFKEEEEAIKVDLHE HHHHHHHHHCCCCCC	40.10	7681157
4309	Ubiquitination	VFKEEEEAIKVDLHE HHHHHHHHHCCCCCC	40.10	-
4321	Phosphorylation	LHEGCGRTKLFWLMA CCCCCCHHHHHHHHH	2.21	20068231
4325	Phosphorylation	CGRTKLFWLMALADS CCHHHHHHHHHHCCC	52.33	27251275
4327	Phosphorylation	RTKLFWLMALADSKT HHHHHHHHHHCCCHH	34.69	27251275
4332	Phosphorylation	WLMALADSKTMKAMV HHHHHCCCHHHHHHH	5.44	20068231
4334	Phosphorylation	MALADSKTMKAMVEF HHHCCCHHHHHHHHH	17.22	27251789
4344	Phosphorylation	AMVEFREHTGKPTTS HHHHHHHHCCCCCCC	6.31	27251789
4347	Ubiquitination	EFREHTGKPTTSSSE HHHHHCCCCCCCHHH	3.39	-
4363	Phosphorylation	CRFCGSRSGTELSAV HHHCCCCCCCCEEEC	63.01	27251275
4403	Ubiquitination	PCGGVKNEEHCLPCL CCCCCCCCCCCHHHH	9.46	24816145
4471	Ubiquitination	LGPRITFGFISCPIC CCCCEEEEEECCHHH	5.24	24816145
4473	Phosphorylation	PRITFGFISCPICKN CCEEEEEECCHHHCC	21.64	25839225
4474	Ubiquitination	RITFGFISCPICKNK CEEEEEECCHHHCCC	46.00	24816145
4484	Phosphorylation	ICKNKINHIVLKDLL HHCCCCCCHHHHHHH	16.36	-
4490	Ubiquitination	NHIVLKDLLDPIKEL CCHHHHHHHHHHHHH	14.21	24816145
4507	Phosphorylation	DVRRKALMRLEYEGL HHHHHHHHHHHHCCC	11.77	22817900
4508	Ubiquitination	VRRKALMRLEYEGLH HHHHHHHHHHHCCCC	23.57	24816145
4513	Ubiquitination	LMRLEYEGLHKSEAI HHHHHHCCCCCCCCC	13.04	24816145
4526	Ubiquitination	AITTPGVRFYNDPAG CCCCCCCEECCCHHH	53.03	24816145
4530	Ubiquitination	PGVRFYNDPAGYAMN CCCEECCCHHHHCHH	32.36	24816145
4534	Ubiquitination	FYNDPAGYAMNRYAY ECCCHHHHCHHHHHH	48.12	24816145
4538	Ubiquitination	PAGYAMNRYAYYVCY HHHHCHHHHHHHHHH	23.71	24816145
4549	Ubiquitination	YVCYKCRKAYFGGEA HHHHHCHHHHHCCCC	2.42	24816145
4551	Ubiquitination	CYKCRKAYFGGEARC HHHCHHHHHCCCCCC	50.14	-
4559	Ubiquitination	FGGEARCDAEAGRGD HCCCCCCCCCCCCCC	19.96	24816145
4560	Ubiquitination	GGEARCDAEAGRGDD CCCCCCCCCCCCCCC	11.67	24816145
4568	Ubiquitination	EAGRGDDYDPRELIC CCCCCCCCCHHHHHH	3.98	24816145
4574	Ubiquitination	DYDPRELICGACSDV CCCHHHHHHHCCCCC	30.77	24816145
4589	Ubiquitination	SRAQMCPKHGTDFLE HHHHCCCCCCCCHHH	2.10	-
4590	Ubiquitination	RAQMCPKHGTDFLEY HHHCCCCCCCCHHHH	26.20	24816145
4591	Phosphorylation	AQMCPKHGTDFLEYK HHCCCCCCCCHHHHH	27.79	24719451
4598	Ubiquitination	GTDFLEYKCRYCCSV CCCHHHHHHHHHHHH	30.25	-
4601	Ubiquitination	FLEYKCRYCCSVAVF HHHHHHHHHHHHHHH	36.90	24816145
4607	Ubiquitination	RYCCSVAVFFCFGTT HHHHHHHHHHHHCCC	58.81	24816145
4608	Ubiquitination	YCCSVAVFFCFGTTH HHHHHHHHHHHCCCH	54.11	24816145
4623	Ubiquitination	FCNACHDDFQRMTSI HHHHCHHHHHHHHCC	62.77	24816145
4624	Ubiquitination	CNACHDDFQRMTSIP HHHCHHHHHHHHCCC	37.90	24816145
4626	Ubiquitination	ACHDDFQRMTSIPKE HCHHHHHHHHCCCHH	37.25	24816145
4632	Ubiquitination	QRMTSIPKEELPHCP HHHHCCCHHHCCCCC	21.55	24816145
4634	Ubiquitination	MTSIPKEELPHCPAG HHCCCHHHCCCCCCC	1.36	24816145
4643	Ubiquitination	PHCPAGPKGKQLEGT CCCCCCCCCCCCCCC		24816145
4645	Ubiquitination	CPAGPKGKQLEGTEC CCCCCCCCCCCCCCC		-
4649	Ubiquitination	PKGKQLEGTECPLHV CCCCCCCCCCCCEEE		24816145
4660	Ubiquitination	PLHVVHPPTGEEFAL CEEEECCCCCCCCHH		24816145
4665	Ubiquitination	HPPTGEEFALGCGVC CCCCCCCCHHHCCCC		24816145
4668	Ubiquitination	TGEEFALGCGVCRNA CCCCCHHHCCCCCCC		24816145

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
3478	S	Phosphorylation	Kinase	CHEK1	O14757	GPS

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MYCB2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MYCB2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MYC_HUMAN	MYC	physical	9689053
FBSP1_HUMAN	FBXO45	physical	19398581
ROBO2_HUMAN	ROBO2	genetic	23525682
FBSP1_HUMAN	FBXO45	physical	25143387
MYC_HUMAN	MYC	physical	26517351

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Acetylation

"Lysine acetylation targets protein complexes and co-regulates majorcellular functions.";
Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.;
Science 325:834-840(2009).
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-1790 AND LYS-2422, AND MASSSPECTROMETRY.
PubMed: 19608861

Phosphorylation

"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions.";
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.;
Sci. Signal. 2:RA46-RA46(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-2645; SER-2751;SER-2882; SER-3440 AND SER-3467, AND MASS SPECTROMETRY.
PubMed: 19690332

"Large-scale proteomics analysis of the human kinome.";
Oppermann F.S., Gnad F., Olsen J.V., Hornberger R., Greff Z., Keri G.,Mann M., Daub H.;
Mol. Cell. Proteomics 8:1751-1764(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2831; SER-3467 ANDSER-3758, AND MASS SPECTROMETRY.
PubMed: 19369195

"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach.";
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.;
Anal. Chem. 81:4493-4501(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-3422; SER-3467 ANDSER-3894, AND MASS SPECTROMETRY.
PubMed: 19413330

"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-140; SER-143; SER-145;THR-2645; SER-2751; SER-3440; SER-3467; SER-3893 AND SER-3894, ANDMASS SPECTROMETRY.
PubMed: 18669648

"Kinase-selective enrichment enables quantitative phosphoproteomics ofthe kinome across the cell cycle.";
Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R.,Greff Z., Keri G., Stemmann O., Mann M.;
Mol. Cell 31:438-448(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-3467, AND MASSSPECTROMETRY.
PubMed: 18691976

"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2749; SER-2751;SER-2831; SER-3052; SER-3893 AND SER-3894, AND MASS SPECTROMETRY.
PubMed: 17081983

"Large-scale characterization of HeLa cell nuclear phosphoproteins.";
Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J.,Li J., Cohn M.A., Cantley L.C., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2774, AND MASSSPECTROMETRY.
PubMed: 15302935