MUSC_HUMAN - dbPTM
MUSC_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MUSC_HUMAN
UniProt AC O60682
Protein Name Musculin
Gene Name MSC
Organism Homo sapiens (Human).
Sequence Length 206
Subcellular Localization Nucleus.
Protein Description Transcription repressor capable of inhibiting the transactivation capability of TCF3/E47. May play a role in regulating antigen-dependent B-cell differentiation..
Protein Sequence MSTGSVSDPEEMELRGLQREYPVPASKRPPLRGVERSYASPSDNSSAEEEDPDGEEERCALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYENGYVHPVNLTWPFVVSGRPDSDTKEVSAANRLCGTTA
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MSTGSVSDP
------CCCCCCCCH
41.2830108239
3Phosphorylation-----MSTGSVSDPE
-----CCCCCCCCHH
31.9830108239
5Phosphorylation---MSTGSVSDPEEM
---CCCCCCCCHHHH
20.6630108239
7Phosphorylation-MSTGSVSDPEEMEL
-CCCCCCCCHHHHHH
49.5030108239
21PhosphorylationLRGLQREYPVPASKR
HHCCCCCCCCCHHHC
16.24-
27UbiquitinationEYPVPASKRPPLRGV
CCCCCHHHCCCCCCC
71.65-
45PhosphorylationYASPSDNSSAEEEDP
CCCCCCCCCCCCCCC
35.60-
46PhosphorylationASPSDNSSAEEEDPD
CCCCCCCCCCCCCCC
46.05-
128PhosphorylationRVLSKAFSRLKTSLP
HHHHHHHHHHHHCCC
41.3826437602
132PhosphorylationKAFSRLKTSLPWVPP
HHHHHHHHCCCCCCC
39.8426074081
133PhosphorylationAFSRLKTSLPWVPPD
HHHHHHHCCCCCCCC
30.7426074081
141PhosphorylationLPWVPPDTKLSKLDT
CCCCCCCCCHHHHHH
39.3926074081
144PhosphorylationVPPDTKLSKLDTLRL
CCCCCCHHHHHHHHH
32.5026074081
148PhosphorylationTKLSKLDTLRLASSY
CCHHHHHHHHHHHHH
24.9826074081

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MUSC_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MUSC_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MUSC_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ID2_HUMANID2physical
11560778

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MUSC_HUMAN

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Related Literatures of Post-Translational Modification

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