MU161_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MU161_SCHPO
• UniProt AC: Q10414
• Protein Name: CWF19-like protein mug161
• Gene Name: mug161
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 561
• Subcellular Localization: Nucleus .
• Protein Description: Has a role in meiosis..
• Protein Sequence: MIFYDKLKPADVLVIGSADGRVIEAIEYIADLHKQHGFKFAICLGNLFSHKRTTSADVVKLKNEKVKVPIPVYFGVGTAGLPESIISHMAMYGPEVAPNLFCMGICGFMKTFYKFTIAQLGGSYNEEKYYQPPEKFEQSLNEKCFHRSDVQKLSKRCDILFSSEWPEDVQENSTLPERKLPKGCMPLAALAANCMPQYFFVPGPVYYEREPYKNSAAINVNTGTVTHFVALAPFKNSKNEKFSYAFTLYPLTTEYMQPAPPNCTASPFEHRPIPLKRASEDQIIPQQTNKFHKSKSSTALFKSKKDSSSSLNKMHKSESHSALNNLHKSESGTSLNNRRSKVGPGSCFFCLSNPNVALHLIVAIGNEAYMALPKGPLTTTASNTPALASSGHVLIIPIAHASALSTLSDTSYEKTLNEMNRFRKAVTDMYNACDSDALVYEISRANGVHLHWQMIPIPKISSHRIESVFLEMAKEAGYDFEERDVEPHELNYFRVFLPSGKILIHRLQLRERFDLQFGRRAAAKILGLEDRVDWRKCVQTEDEEKAESEAFKMCFKPYDFT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
53	Phosphorylation	NLFSHKRTTSADVVK CCCCCCCCCCCCEEE	29.88	24763107
55	Phosphorylation	FSHKRTTSADVVKLK CCCCCCCCCCEEECC	23.12	27738172
279	Phosphorylation	PIPLKRASEDQIIPQ CCCCCCCCCCCCCCC	45.82	28889911
288	Phosphorylation	DQIIPQQTNKFHKSK CCCCCCCCCCCCCCC	34.82	29996109
294	Phosphorylation	QTNKFHKSKSSTALF CCCCCCCCCCHHHHH	29.24	21712547
296	Phosphorylation	NKFHKSKSSTALFKS CCCCCCCCHHHHHHC	39.76	28889911
297	Phosphorylation	KFHKSKSSTALFKSK CCCCCCCHHHHHHCC	22.80	29996109
298	Phosphorylation	FHKSKSSTALFKSKK CCCCCCHHHHHHCCC	34.18	28889911
303	Phosphorylation	SSTALFKSKKDSSSS CHHHHHHCCCCCCHH	37.29	21712547
307	Phosphorylation	LFKSKKDSSSSLNKM HHHCCCCCCHHHHHH	40.79	24763107
308	Phosphorylation	FKSKKDSSSSLNKMH HHCCCCCCHHHHHHH	33.80	21712547
309	Phosphorylation	KSKKDSSSSLNKMHK HCCCCCCHHHHHHHH	42.68	24763107
310	Phosphorylation	SKKDSSSSLNKMHKS CCCCCCHHHHHHHHH	37.60	21712547
317	Phosphorylation	SLNKMHKSESHSALN HHHHHHHHHCHHHHH	29.65	28889911
319	Phosphorylation	NKMHKSESHSALNNL HHHHHHHCHHHHHHH	29.81	28889911
321	Phosphorylation	MHKSESHSALNNLHK HHHHHCHHHHHHHHH	43.67	25720772
329	Phosphorylation	ALNNLHKSESGTSLN HHHHHHHCCCCCCCC	26.67	21712547
331	Phosphorylation	NNLHKSESGTSLNNR HHHHHCCCCCCCCCC	55.23	28889911
333	Phosphorylation	LHKSESGTSLNNRRS HHHCCCCCCCCCCCC	39.04	21712547
334	Phosphorylation	HKSESGTSLNNRRSK HHCCCCCCCCCCCCC	32.40	28889911
340	Phosphorylation	TSLNNRRSKVGPGSC CCCCCCCCCCCCCCE	28.58	24763107
462	Phosphorylation	IPIPKISSHRIESVF EECCCCCHHHHHHHH	21.91	27738172
467	Phosphorylation	ISSHRIESVFLEMAK CCHHHHHHHHHHHHH	18.79	27738172

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MU161_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MU161_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MU161_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
YFE6_SCHPO	gmh5	genetic	18818364
YNU4_SCHPO	SPBC28E12.04	genetic	22681890
PPR8_SCHPO	ppr8	genetic	22681890

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-296; THR-298; SER-317;SER-319; SER-331 AND SER-334, AND MASS SPECTROMETRY.
PubMed: 18257517