MTURN_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MTURN_HUMAN
• UniProt AC: Q8N3F0
• Protein Name: Maturin
• Gene Name: MTURN
• Organism: Homo sapiens (Human).
• Sequence Length: 131
• Protein Description: May be involved in early neuronal development..
• Protein Sequence: MDFQQLADVAEKWCSNTPFELIATEETERRMDFYADPGVSFYVLCPDNGCGDNFHVWSESEDCLPFLQLAQDYISSCGKKTLHEVLEKVFKSFRPLLGLPDADDDAFEEYSADVEEEEPEADHPQMGVSQQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
34	Phosphorylation	TERRMDFYADPGVSF HHHHHHHHCCCCCEE		24681962
47 (in isoform 3)	Ubiquitination	-		21890473
55 (in isoform 3)	Ubiquitination	-		21890473
58	Phosphorylation	GDNFHVWSESEDCLP CCCEEEEECCCCHHH		-
79	Ubiquitination	DYISSCGKKTLHEVL HHHHHCCHHHHHHHH		23000965
80	Ubiquitination	YISSCGKKTLHEVLE HHHHCCHHHHHHHHH		23000965
80 (in isoform 1)	Ubiquitination	-		21890473
80 (in isoform 2)	Ubiquitination	-		21890473
88	Acetylation	TLHEVLEKVFKSFRP HHHHHHHHHHHHHHH		25953088
88	Ubiquitination	TLHEVLEKVFKSFRP HHHHHHHHHHHHHHH		23000965
88 (in isoform 1)	Ubiquitination	-		21890473
88 (in isoform 2)	Ubiquitination	-		21890473
91	Ubiquitination	EVLEKVFKSFRPLLG HHHHHHHHHHHHHHC		23000965
110	Phosphorylation	DDDAFEEYSADVEEE CCHHHHHHCCCCCCC		27642862
129	Phosphorylation	DHPQMGVSQQ----- CCCCCCCCCC-----		28348404

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
58	S	Phosphorylation	Kinase	CHUK	O15111	GPS
58	S	Phosphorylation	Kinase	IKBKB	O14920	GPS

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MTURN_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MTURN_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.