MSMO1_HUMAN - dbPTM
MSMO1_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MSMO1_HUMAN
UniProt AC Q15800
Protein Name Methylsterol monooxygenase 1
Gene Name MSMO1
Organism Homo sapiens (Human).
Sequence Length 293
Subcellular Localization Endoplasmic reticulum membrane
Multi-pass membrane protein .
Protein Description Catalyzes the first step in the removal of the two C-4 methyl groups of 4,4-dimethylzymosterol..
Protein Sequence MATNESVSIFSSASLAVEYVDSLLPENPLQEPFKNAWNYMLNNYTKFQIATWGSLIVHEALYFLFCLPGFLFQFIPYMKKYKIQKDKPETWENQWKCFKVLLFNHFCIQLPLICGTYYFTEYFNIPYDWERMPRWYFLLARCFGCAVIEDTWHYFLHRLLHHKRIYKYIHKVHHEFQAPFGMEAEYAHPLETLILGTGFFIGIVLLCDHVILLWAWVTIRLLETIDVHSGYDIPLNPLNLIPFYAGSRHHDFHHMNFIGNYASTFTWWDRIFGTDSQYNAYNEKRKKFEKKTE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
32UbiquitinationPENPLQEPFKNAWNY
CCCCCCCCCHHHHHH		32.3322817900
36UbiquitinationLQEPFKNAWNYMLNN
CCCCCHHHHHHHHHC		9.1121890473
36UbiquitinationLQEPFKNAWNYMLNN
CCCCCHHHHHHHHHC		9.1121890473
40UbiquitinationFKNAWNYMLNNYTKF
CHHHHHHHHHCCCCC		2.6722817900
80UbiquitinationQFIPYMKKYKIQKDK
HHHHHHHHHCCCCCC		34.9322817900
82UbiquitinationIPYMKKYKIQKDKPE
HHHHHHHCCCCCCCC		47.7622817900
85UbiquitinationMKKYKIQKDKPETWE
HHHHCCCCCCCCCHH		71.8021906983
87UbiquitinationKYKIQKDKPETWENQ
HHCCCCCCCCCHHHH		52.3621906983
96UbiquitinationETWENQWKCFKVLLF
CCHHHHHHHHHHHHH		21.7429967540
153UbiquitinationAVIEDTWHYFLHRLL
HHHHHHHHHHHHHHH		12.9321890473
153UbiquitinationAVIEDTWHYFLHRLL
HHHHHHHHHHHHHHH		12.9323000965
155UbiquitinationIEDTWHYFLHRLLHH
HHHHHHHHHHHHHHH		2.7523000965
156UbiquitinationEDTWHYFLHRLLHHK
HHHHHHHHHHHHHHH		1.4923000965
159UbiquitinationWHYFLHRLLHHKRIY
HHHHHHHHHHHHHHH		3.5723000965
160UbiquitinationHYFLHRLLHHKRIYK
HHHHHHHHHHHHHHH		3.9224816145
163UbiquitinationLHRLLHHKRIYKYIH
HHHHHHHHHHHHHHH		29.7322817900
167UbiquitinationLHHKRIYKYIHKVHH
HHHHHHHHHHHHHHH		35.0422817900
171UbiquitinationRIYKYIHKVHHEFQA
HHHHHHHHHHHHHCC		33.4322817900
274PhosphorylationWWDRIFGTDSQYNAY
HHHHHHCCHHHHHHH		23.0228796482
276PhosphorylationDRIFGTDSQYNAYNE
HHHHCCHHHHHHHHH		34.1128796482
278PhosphorylationIFGTDSQYNAYNEKR
HHCCHHHHHHHHHHH		13.0028796482
281PhosphorylationTDSQYNAYNEKRKKF
CHHHHHHHHHHHHHH		21.8828796482
284UbiquitinationQYNAYNEKRKKFEKK
HHHHHHHHHHHHHHH		66.9223000965
286UbiquitinationNAYNEKRKKFEKKTE
HHHHHHHHHHHHHCC		73.2523000965
287UbiquitinationAYNEKRKKFEKKTE-
HHHHHHHHHHHHCC-		63.8923000965
290UbiquitinationEKRKKFEKKTE----
HHHHHHHHHCC----		69.0323000965
291UbiquitinationKRKKFEKKTE-----
HHHHHHHHCC-----		51.1724816145
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MSMO1_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MSMO1_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MSMO1_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ODPAT_HUMANPDHA2physical
22939629
MIC60_HUMANIMMTphysical
22939629
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MSMO1_HUMAN

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Related Literatures of Post-Translational Modification

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