dbPTM

MSI5_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	MSI5_ARATH
UniProt AC	Q9SU78
Protein Name	WD-40 repeat-containing protein MSI5
Gene Name	MSI5
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	487
Subcellular Localization	Nucleus.
Protein Description	Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA..
Protein Sequence	MESEAAATVQATRPRRAPRTPVTAILTDKRRRKPKSNNESQLPFLLQQSQKATVDDTYSQWKTLLPILYDSFVNHTLVWPSLSCRWGPQLEQAGSKTQRLYLSEQTNGSVPNTLVIANCETVNRQLNEKAHSPFVKKYKTIIHPGEVNRIRELPQNSKIVATHTDSPDILIWNTETQPDRYAVLGAPDSRPDLLLIGHQDDAEFALAMCPTEPFVLSGGKDKSVILWNIQDHITMAGSDSKSPGSSFKQTGEGSDKTGGPSVGPRGIYNGHKDTVEDVAFCPSSAQEFCSVGDDSCLMLWDARTGTSPAMKVEKAHDADLHCVDWNPHDNNLILTGSADNTVRVFDRRNLTSNGVGSPVYKFEGHRAAVLCVQWSPDKSSVFGSSAEDGLLNIWDCDRVGKKSERATKTPDGLFFQHAGHRDKVVDFHWSLLNPWTIVSVSDNCESIGGGGTLQIWRMSDLIYRPEDEVLTELEKFKSHVFTCTSKS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
1	Acetylation	-------MESEAAAT -------CCCHHHHH	13.27	-
242	Phosphorylation	MAGSDSKSPGSSFKQ ECCCCCCCCCCCCCC	38.14	28011693

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of MSI5_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of MSI5_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of MSI5_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
HDA6_ARATH	HDA6	physical	22102827

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of MSI5_ARATH

Related Literatures of Post-Translational Modification