MRRP1_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MRRP1_DROME
• UniProt AC: Q7JUX9
• Protein Name: Mitochondrial ribonuclease P protein 1 homolog
• Gene Name: trmt10c
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 446
• Subcellular Localization: Mitochondrion.
• Protein Description: May function in mitochondrial tRNA maturation..
• Protein Sequence: MLKHFARWRLGSQLLKGCAAPVRQASKTSSAENLIAGTEEPQKKFVNPFSQPAPALSNDTISENKEERDKRLKVLQLEADIAHQEGRRVPSLEFFKDHHWEHVLTLPTKSARIKYFGYLWQIEMKKEADQRKKAERAKEAERRVAEMRKEREENTHIIYGLGHTSLFLRIYDTTINHWQNNRLTRAMQFAPKMVLDCSYDEHMNNREATYAAKQLMMCFAENRMNDEPFDLHYCNTQMDSRCMQSLQRYIPTMHNPEFPINLHSKCFTELFPKQNLVYLTPHCREDLVTYNPDDIYIVGAMVDTMNNEPLSLAKAKRLGLRMARLPLDRYLQWGSGSGKSLTLNQMINIMLDLKKTGDWDTALKHVPRRKVVQNEFQPRREKDHWSTGTRARKLNMRIDHLFDFDENRRQATSYATPQNVRQRREGLEFQLDTWATGKQKKKQRQN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
50	Phosphorylation	KKFVNPFSQPAPALS HHCCCCCCCCCCCCC	36.19	22817900
57	Phosphorylation	SQPAPALSNDTISEN CCCCCCCCCCCCCCC	34.46	22817900
60	Phosphorylation	APALSNDTISENKEE CCCCCCCCCCCCHHH	30.56	22817900
62	Phosphorylation	ALSNDTISENKEERD CCCCCCCCCCHHHHH	36.89	22817900

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MRRP1_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MRRP1_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MRRP1_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HCD2_DROME	scu	physical	14605208
HCD2_DROME	scu	physical	27131785

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of Drosophila melanogaster embryos.";
Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P.;
J. Proteome Res. 7:1675-1682(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-50; SER-57; THR-60 ANDSER-62, AND MASS SPECTROMETRY.
PubMed: 18327897