MPZL3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MPZL3_HUMAN
• UniProt AC: Q6UWV2
• Protein Name: Myelin protein zero-like protein 3
• Gene Name: MPZL3
• Organism: Homo sapiens (Human).
• Sequence Length: 235
• Subcellular Localization: Membrane ; Single-pass type I membrane protein .
• Protein Description: Mediates homophilic cell-cell adhesion..
• Protein Sequence: MQQRGAAGSRGCALFPLLGVLFFQGVYIVFSLEIRADAHVRGYVGEKIKLKCTFKSTSDVTDKLTIDWTYRPPSSSHTVSIFHYQSFQYPTTAGTFRDRISWVGNVYKGDASISISNPTIKDNGTFSCAVKNPPDVHHNIPMTELTVTERGFGTMLSSVALLSILVFVPSAVVVALLLVRMGRKAAGLKKRSRSGYKKSSIEVSDDTDQEEEEACMARLCVRCAECLDSDYEETY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
31	Phosphorylation	QGVYIVFSLEIRADA CCEEEEEEEEEECCE	17.75	24719451
123	N-linked_Glycosylation	SNPTIKDNGTFSCAV CCCEECCCCEEEEEE	46.53	UniProtKB CARBOHYD
204	Phosphorylation	KKSSIEVSDDTDQEE CCCEEEECCCCCHHH	19.58	25849741
207	Phosphorylation	SIEVSDDTDQEEEEA EEEECCCCCHHHHHH	44.57	25849741
229	Phosphorylation	RCAECLDSDYEETY- HHHHHHCCCCCCCC-	29.19	25159151

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MPZL3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MPZL3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MPZL3_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MPZL2_HUMAN	MPZL2	physical	21982860

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.