MP17L_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MP17L_HUMAN
• UniProt AC: Q2QL34
• Protein Name: Mpv17-like protein
• Gene Name: MPV17L
• Organism: Homo sapiens (Human).
• Sequence Length: 196
• Subcellular Localization: Isoform 1: Peroxisome membrane ; Multi-pass membrane protein.
• Protein Description: Isoform 1 participates in reactive oxygen species metablism by up- or down-regulation of the genes of antioxidant enzymes..
• Protein Sequence: MAGWWPALSRAARRHPWPTNVLLYGSLVSAGDALQQRLQGREANWRQTRRVATLVVTFHANFNYVWLRLLERALPGRAPHALLAKLLCDQVVGAPIAVSAFYVGMSILQGKDDIFLDLKQKFWNTYLSGLMYWPFVQLTNFSLVPVQWRTAYAGVCGFLWATFICFSQQSGDGTFKSAFTILYTKGTSATEGYPKK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
180	O-linked_Glycosylation	GTFKSAFTILYTKGT CCEEEEEEEEEECCC	15.13	OGP
183	Phosphorylation	KSAFTILYTKGTSAT EEEEEEEEECCCCCC	11.53	-
184	Phosphorylation	SAFTILYTKGTSATE EEEEEEEECCCCCCC	21.39	-
193	Phosphorylation	GTSATEGYPKK---- CCCCCCCCCCC----	12.97	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MP17L_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MP17L_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MP17L_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.