MOT14_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MOT14_HUMAN
• UniProt AC: Q7RTX9
• Protein Name: Monocarboxylate transporter 14
• Gene Name: SLC16A14
• Organism: Homo sapiens (Human).
• Sequence Length: 510
• Subcellular Localization: Cell membrane; Multi-pass membrane protein.
• Protein Description: Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane..
• Protein Sequence: MYTSHEDIGYDFEDGPKDKKTLKPHPNIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRGLTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVHYLFITFGVAAGLGSGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMLIQGAVSLNLCVCGALMRPLSPGKNPNDPGEKDVRGLPAHSTESVKSTGQQGRTEEKDGGLGNEETLCDLQAQECPDQAGHRKNMCALRILKTVSWLTMRVRKGFEDWYSGYFGTASLFTNRMFVAFIFWALFAYSSFVIPFIHLPEIVNLYNLSEQNDVFPLTSIIAIVHIFGKVILGVIADLPCISVWNVFLLANFTLVLSIFILPLMHTYAGLAVICALIGFSSGYFSLMPVVTEDLVGIEHLANAYGIIICANGISALLGPPFAGWIYDITQKYDFSFYICGLLYMIGILFLLIQPCIRIIEQSRRKYMDGAHV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MYTSHEDIG ------CCCCHHHCC	19.56	28348404
3	Phosphorylation	-----MYTSHEDIGY -----CCCCHHHCCC	23.47	28348404
4	Phosphorylation	----MYTSHEDIGYD ----CCCCHHHCCCC	13.85	22617229
10	Phosphorylation	TSHEDIGYDFEDGPK CCHHHCCCCCCCCCC	20.14	25884760
165	Phosphorylation	ALAQGLSTTGTGFGT HHHHCCCCCCCCHHH	34.00	-
176	Phosphorylation	GFGTFLMTVLLKYLC CHHHHHHHHHHHHHH	15.34	-
213	Phosphorylation	GALMRPLSPGKNPND HHHHCCCCCCCCCCC	34.00	24719451
233	Phosphorylation	VRGLPAHSTESVKST CCCCCCCCCCHHHCC	35.66	28176443
234	Phosphorylation	RGLPAHSTESVKSTG CCCCCCCCCHHHCCC	23.55	26471730
236	Phosphorylation	LPAHSTESVKSTGQQ CCCCCCCHHHCCCCC	34.63	24173317
238	Ubiquitination	AHSTESVKSTGQQGR CCCCCHHHCCCCCCC	52.13	-
419	Phosphorylation	CALIGFSSGYFSLMP HHHHCCCCCCHHHCC	34.94	25137130

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MOT14_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MOT14_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MOT14_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
GNAQ_HUMAN	GNAQ	physical	26186194
YES_HUMAN	YES1	physical	26186194
GNAQ_HUMAN	GNAQ	physical	28514442
SVIP_HUMAN	SVIP	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.