MNT_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MNT_MOUSE
• UniProt AC: O08789
• Protein Name: Max-binding protein MNT
• Gene Name: Mnt
• Organism: Mus musculus (Mouse).
• Sequence Length: 591
• Subcellular Localization: Nucleus.
• Protein Description: Binds DNA as a heterodimer with MAX and represses transcription. Binds to the canonical E box sequence 5'-CACGTG-3' and, with higher affinity, to 5'-CACGCG-3'..
• Protein Sequence: MSIETLLEAARFLEWQAQQQQRAREEQERLRLEREREREQEQKRASNLARLAHALPVEEPRIEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQSLPPPPPLPPAAQPLPLAPRQPALVSTPGLSIKEPVTLPTRPQVPTPAPLLPDAKTTVAPTGSPKPLQPLPAPILTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEAKSSEQKKRPGGIGTREVHNKLEKNRRAHLKECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELKHELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNVDEEMEGDRAGLGPPKLNHRPQPELLKSALPTPSTAPAPLPTHPHPHPHPVALSPAHLPVQQQQPPQQKTPLPAPPPPPATPTQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQLAPATPPIGHITVHPATLNHVAHLGSQLPLYPQPVAVSQPVAVSHIAHTLSHQQVNGTAGLGPPATVMAKPAVGAQVVHHPQLVGQTVLNPVTMVTMPSFPVSTLKLA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MSIETLLEA ------CCHHHHHHH	29.18	-
157	Phosphorylation	PLLPDAKTTVAPTGS CCCCCCCCEECCCCC	28.37	24759943
158	Phosphorylation	LLPDAKTTVAPTGSP CCCCCCCEECCCCCC	17.60	26060331
162	Phosphorylation	AKTTVAPTGSPKPLQ CCCEECCCCCCCCCC	40.32	25266776
164	Phosphorylation	TTVAPTGSPKPLQPL CEECCCCCCCCCCCC	32.03	29472430
330	Phosphorylation	QPEDDQASTSTASEG CCCCCCCCCCCCCCC	19.77	25338131
331	Phosphorylation	PEDDQASTSTASEGE CCCCCCCCCCCCCCC	32.86	25338131
332	Phosphorylation	EDDQASTSTASEGED CCCCCCCCCCCCCCC	21.34	25338131
333	Phosphorylation	DDQASTSTASEGEDN CCCCCCCCCCCCCCC	34.00	25338131
335	Phosphorylation	QASTSTASEGEDNVD CCCCCCCCCCCCCCC	46.34	25338131
394	Phosphorylation	HPHPVALSPAHLPVQ CCCCCCCCCCCCCCC	15.42	27841257

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MNT_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MNT_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MNT_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SIN3B_MOUSE	Sin3b	physical	16103876
SIN3A_MOUSE	Sin3a	physical	16103876
HDAC1_MOUSE	Hdac1	physical	16103876

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.