UniProt ID | MFSD5_HUMAN | |
---|---|---|
UniProt AC | Q6N075 | |
Protein Name | Molybdate-anion transporter | |
Gene Name | MFSD5 | |
Organism | Homo sapiens (Human). | |
Sequence Length | 450 | |
Subcellular Localization |
Cell membrane Multi-pass membrane protein . |
|
Protein Description | Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.. | |
Protein Sequence | MLVTAYLAFVGLLASCLGLELSRCRAKPPGRACSNPSFLRFQLDFYQVYFLALAADWLQAPYLYKLYQHYYFLEGQIAILYVCGLASTVLFGLVASSLVDWLGRKNSCVLFSLTYSLCCLTKLSQDYFVLLVGRALGGLSTALLFSAFEAWYIHEHVERHDFPAEWIPATFARAAFWNHVLAVVAGVAAEAVASWIGLGPVAPFVAAIPLLALAGALALRNWGENYDRQRAFSRTCAGGLRCLLSDRRVLLLGTIQALFESVIFIFVFLWTPVLDPHGAPLGIIFSSFMAASLLGSSLYRIATSKRYHLQPMHLLSLAVLIVVFSLFMLTFSTSPGQESPVESFIAFLLIELACGLYFPSMSFLRRKVIPETEQAGVLNWFRVPLHSLACLGLLVLHDSDRKTGTRNMFSICSAVMVMALLAVVGLFTVVRHDAELRVPSPTEEPYAPEL | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
15 | Phosphorylation | AFVGLLASCLGLELS HHHHHHHHHHCHHHH | 15.16 | - | |
22 | Phosphorylation | SCLGLELSRCRAKPP HHHCHHHHHHCCCCC | 21.69 | - | |
107 (in isoform 2) | Phosphorylation | - | 14.50 | - | |
111 (in isoform 2) | Phosphorylation | - | 2.54 | 27642862 | |
113 (in isoform 2) | Phosphorylation | - | 4.00 | 27642862 | |
129 (in isoform 2) | Phosphorylation | - | 3.08 | 27642862 | |
236 | S-palmitoylation | QRAFSRTCAGGLRCL HHHHHHHHHHHHHHH | 3.00 | 29575903 | |
242 | S-palmitoylation | TCAGGLRCLLSDRRV HHHHHHHHHHCCCCH | 5.58 | 29575903 | |
367 | Ubiquitination | SMSFLRRKVIPETEQ CHHHHHHCCCCHHHH | 37.77 | 22817900 | |
367 (in isoform 1) | Ubiquitination | - | 37.77 | 21890473 | |
440 | Phosphorylation | DAELRVPSPTEEPYA CCCCCCCCCCCCCCC | 41.41 | 25849741 | |
442 | Phosphorylation | ELRVPSPTEEPYAPE CCCCCCCCCCCCCCC | 58.27 | 30266825 | |
446 | Phosphorylation | PSPTEEPYAPEL--- CCCCCCCCCCCC--- | 37.76 | 29978859 | |
474 | Ubiquitination | ------------------------------- ------------------------------- | 21890473 | ||
547 (in isoform 2) | Phosphorylation | - | 24719451 | ||
553 (in isoform 2) | Phosphorylation | - | 27642862 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MFSD5_HUMAN !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MFSD5_HUMAN !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MFSD5_HUMAN !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
PEX19_HUMAN | PEX19 | physical | 21988832 | |
CR3L1_HUMAN | CREB3L1 | physical | 25416956 | |
KASH5_HUMAN | CCDC155 | physical | 25416956 | |
CR3L1_HUMAN | CREB3L1 | physical | 21516116 | |
G3PT_HUMAN | GAPDHS | physical | 28514442 |
Kegg Disease | ||||||
---|---|---|---|---|---|---|
There are no disease associations of PTM sites. | ||||||
OMIM Disease | ||||||
There are no disease associations of PTM sites. | ||||||
Kegg Drug | ||||||
There are no disease associations of PTM sites. | ||||||
DrugBank | ||||||
There are no disease associations of PTM sites. |
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