MFSD5_HUMAN - dbPTM
MFSD5_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MFSD5_HUMAN
UniProt AC Q6N075
Protein Name Molybdate-anion transporter
Gene Name MFSD5
Organism Homo sapiens (Human).
Sequence Length 450
Subcellular Localization Cell membrane
Multi-pass membrane protein .
Protein Description Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum..
Protein Sequence MLVTAYLAFVGLLASCLGLELSRCRAKPPGRACSNPSFLRFQLDFYQVYFLALAADWLQAPYLYKLYQHYYFLEGQIAILYVCGLASTVLFGLVASSLVDWLGRKNSCVLFSLTYSLCCLTKLSQDYFVLLVGRALGGLSTALLFSAFEAWYIHEHVERHDFPAEWIPATFARAAFWNHVLAVVAGVAAEAVASWIGLGPVAPFVAAIPLLALAGALALRNWGENYDRQRAFSRTCAGGLRCLLSDRRVLLLGTIQALFESVIFIFVFLWTPVLDPHGAPLGIIFSSFMAASLLGSSLYRIATSKRYHLQPMHLLSLAVLIVVFSLFMLTFSTSPGQESPVESFIAFLLIELACGLYFPSMSFLRRKVIPETEQAGVLNWFRVPLHSLACLGLLVLHDSDRKTGTRNMFSICSAVMVMALLAVVGLFTVVRHDAELRVPSPTEEPYAPEL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
15PhosphorylationAFVGLLASCLGLELS
HHHHHHHHHHCHHHH
15.16-
22PhosphorylationSCLGLELSRCRAKPP
HHHCHHHHHHCCCCC
21.69-
107 (in isoform 2)Phosphorylation-14.50-
111 (in isoform 2)Phosphorylation-2.5427642862
113 (in isoform 2)Phosphorylation-4.0027642862
129 (in isoform 2)Phosphorylation-3.0827642862
236S-palmitoylationQRAFSRTCAGGLRCL
HHHHHHHHHHHHHHH
3.0029575903
242S-palmitoylationTCAGGLRCLLSDRRV
HHHHHHHHHHCCCCH
5.5829575903
367UbiquitinationSMSFLRRKVIPETEQ
CHHHHHHCCCCHHHH
37.7722817900
367 (in isoform 1)Ubiquitination-37.7721890473
440PhosphorylationDAELRVPSPTEEPYA
CCCCCCCCCCCCCCC
41.4125849741
442PhosphorylationELRVPSPTEEPYAPE
CCCCCCCCCCCCCCC
58.2730266825
446PhosphorylationPSPTEEPYAPEL---
CCCCCCCCCCCC---
37.7629978859
474Ubiquitination-------------------------------
-------------------------------
21890473
547 (in isoform 2)Phosphorylation-24719451
553 (in isoform 2)Phosphorylation-27642862

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MFSD5_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MFSD5_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MFSD5_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PEX19_HUMANPEX19physical
21988832
CR3L1_HUMANCREB3L1physical
25416956
KASH5_HUMANCCDC155physical
25416956
CR3L1_HUMANCREB3L1physical
21516116
G3PT_HUMANGAPDHSphysical
28514442

Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MFSD5_HUMAN

loading...

Related Literatures of Post-Translational Modification

TOP