MBI2_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MBI2_YEAST
• UniProt AC: P03873
• Protein Name: Cytochrome b mRNA maturase bI2
• Gene Name: BI2
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 423
• Subcellular Localization: Mitochondrion inner membrane ; Multi-pass membrane protein .
• Protein Description: This protein is responsible for splicing and maturation of cytochrome b mRNA. Specifically, it may be responsible for the splicing specificity of the second intron..
• Protein Sequence: MAFRKSNVYLSLVNSYIIDSPQPSSINYWWNMGSLLGLCLVIQIVTGIFMAMHYSSNIELAFSSVEHIMRDVHNGYILRYLHANGASFFFMVMFMHMAKGLYYGSYRSPRVTLWNVGVIIFILTIATAFLGYCCVYGQMSHWGNMNIASNMFNMMKTIYMMMLMLLIYIFYTIMMRQMMKTKEYTMLIKSMDYINKNKYMINLNMTNKKDMNNNIGPLNMNILSIIYGSMLGDGHAEKRKGGKGTRIVFQQEYCNINYLYYLHSLLANLGYCNTNLPLIKTRLGKKGKIRQYLKFNTWTYDSFNMIYSEWYIKNMSGKGNIKVIPKSLDNYLTPLALAIWIMDDGCKLGKGLKFTTNCFSYKDVQYLTYLLHNKYNIKSTITKGNKENTQFVIYVWKESMPILTKIVSPYIIPSMKYKLGNYL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
157	Phosphorylation	NMFNMMKTIYMMMLM HHHHHHHHHHHHHHH	10.23	28132839
159	Phosphorylation	FNMMKTIYMMMLMLL HHHHHHHHHHHHHHH	5.56	28132839
168	Phosphorylation	MMLMLLIYIFYTIMM HHHHHHHHHHHHHHH	5.73	28132839
171	Phosphorylation	MLLIYIFYTIMMRQM HHHHHHHHHHHHHHH	5.94	28132839
172	Phosphorylation	LLIYIFYTIMMRQMM HHHHHHHHHHHHHHH	7.52	28132839
199	Phosphorylation	DYINKNKYMINLNMT HHHHCCEEEEEEECC	16.78	28889911
206	Phosphorylation	YMINLNMTNKKDMNN EEEEEECCCCHHCCC	42.69	28889911
414	Phosphorylation	VSPYIIPSMKYKLGN CCCCCCCCCCCCCCC	19.93	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MBI2_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MBI2_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MBI2_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NAM7_YEAST	NAM7	genetic	14763985

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.