MAGA9_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MAGA9_HUMAN
• UniProt AC: P43362
• Protein Name: Melanoma-associated antigen 9
• Gene Name: MAGEA9
• Organism: Homo sapiens (Human).
• Sequence Length: 315
• Protein Description: Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression..
• Protein Sequence: MSLEQRSPHCKPDEDLEAQGEDLGLMGAQEPTGEEEETTSSSDSKEEEVSAAGSSSPPQSPQGGASSSISVYYTLWSQFDEGSSSQEEEEPSSSVDPAQLEFMFQEALKLKVAELVHFLLHKYRVKEPVTKAEMLESVIKNYKRYFPVIFGKASEFMQVIFGTDVKEVDPAGHSYILVTALGLSCDSMLGDGHSMPKAALLIIVLGVILTKDNCAPEEVIWEALSVMGVYVGKEHMFYGEPRKLLTQDWVQENYLEYRQVPGSDPAHYEFLWGSKAHAETSYEKVINYLVMLNAREPICYPSLYEEVLGEEQEGV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSLEQRSPH ------CCHHHCCCC	40.38	26074081
7	Phosphorylation	-MSLEQRSPHCKPDE -CCHHHCCCCCCCCH	20.77	26074081
131	Ubiquitination	RVKEPVTKAEMLESV CCCCCCCHHHHHHHH	42.45	29967540
140	Ubiquitination	EMLESVIKNYKRYFP HHHHHHHHHCHHHHH	52.66	21987572
143	Ubiquitination	ESVIKNYKRYFPVIF HHHHHHCHHHHHHHH	50.44	-
243	Ubiquitination	MFYGEPRKLLTQDWV HCCCCCCHHCCHHHH	59.57	21906983
254	Phosphorylation	QDWVQENYLEYRQVP HHHHHHCCHHHCCCC	10.52	-
257	Phosphorylation	VQENYLEYRQVPGSD HHHCCHHHCCCCCCC	12.07	-
288	Phosphorylation	SYEKVINYLVMLNAR CHHHHHHHHHHHCCC	6.91	-
300	Phosphorylation	NAREPICYPSLYEEV CCCCCCCCHHHHHHH	9.14	-
304	Phosphorylation	PICYPSLYEEVLGEE CCCCHHHHHHHHCCC	17.87	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MAGA9_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MAGA9_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MAGA9_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DP13A_HUMAN	APPL1	physical	25416956

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.