dbPTM

LSD2_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	LSD2_DROME
UniProt AC	Q9VXY7
Protein Name	Lipid storage droplets surface-binding protein 2
Gene Name	Lsd-2 {ECO:0000312\|EMBL:AAF48419.1}
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	352
Subcellular Localization	Cytoplasm . Lipid droplet . Cytoplasm and on surface of neutral lipid storage droplets in oocytes. Colocalizes with Lsd-1 to the droplet surface in cells of fat bodies.
Protein Description	Essential for embryogenesis. Required for normal deposition of neutral lipids in the oocyte..
Protein Sequence	MASAEQKHATGNGTTGNGTAMNDVDQPKDAKDLLPHLESLERIIKLPVVNAAWDKSQDVYGKVKGKNRVFEWALTAAEDCVTRAVTTAAPFVTKLDRPIAYVDQTLVKGIDKLEVKAPIIKDTPQEIYNQAKSKVIDVVQPHLERVVKFKAAGQQKAASLKDLAWQKANEVLATQYGSLAVNGVDTTTALAERLLEYYFPKCESDVEEDNDDKQNAVVQNGKSSENDMPVPASEDPVLHTVQTVGRLSNKISRRVYRNVSRQIKQVQKGNINDYLSSLIAALKLHQYINFINSSMGTNVEQSGGSSSDACSPFGTTTSTTTTTTTSSTSNNKPVVALPHVAKSKRAPAVSSQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
159	Phosphorylation	AGQQKAASLKDLAWQ HCHHHCHHHHHHHHH	40.59	22817900
204	Phosphorylation	YYFPKCESDVEEDND HHCCCCCCCCCCCCC	57.32	28490779
248	Phosphorylation	VQTVGRLSNKISRRV HHHHHHHHHHHHHHH	34.41	21082442

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of LSD2_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of LSD2_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of LSD2_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
LSD1_DROME	Lsd-1	genetic	22505614

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of LSD2_DROME

Related Literatures of Post-Translational Modification