LRC57_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LRC57_HUMAN
• UniProt AC: Q8N9N7
• Protein Name: Leucine-rich repeat-containing protein 57
• Gene Name: LRRC57
• Organism: Homo sapiens (Human).
• Sequence Length: 239
• Subcellular Localization: Membrane ; Lipid-anchor .
• Protein Sequence: MGNSALRAHVETAQKTGVFQLKDRGLTEFPADLQKLTSNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCSLRHLDVMDLSKNQIRSIPDSVGELQVIELNLNQNQISQISVKISCCPRLKILRLEENCLELSMLPQSILSDSQICLLAVEGNLFEIKKLRELEGYDKYMERFTATKKKFA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Myristoylation	------MGNSALRAH ------CCCHHHHHH	36.48	25255805
15	Ubiquitination	AHVETAQKTGVFQLK HHHHHHHHHCCEEEC	44.79	-
16	Phosphorylation	HVETAQKTGVFQLKD HHHHHHHHCCEEECC	26.88	-
22	Ubiquitination	KTGVFQLKDRGLTEF HHCCEEECCCCCCCC	34.30	-
35	Ubiquitination	EFPADLQKLTSNLRT CCCHHHHHHHHCCEE	62.11	21890473
37	Phosphorylation	PADLQKLTSNLRTID CHHHHHHHHCCEEEE	23.70	20068231
38	Phosphorylation	ADLQKLTSNLRTIDL HHHHHHHHCCEEEEC	44.28	20068231
42	Phosphorylation	KLTSNLRTIDLSNNK HHHHCCEEEECCCCC	23.24	20068231
46	Phosphorylation	NLRTIDLSNNKIESL CCEEEECCCCCCCCC	34.31	20068231
49	Ubiquitination	TIDLSNNKIESLPPL EEECCCCCCCCCCCC	52.69	-
52	Phosphorylation	LSNNKIESLPPLLIG CCCCCCCCCCCCEEC	50.04	21406692
60	Ubiquitination	LPPLLIGKFTLLKSL CCCCEECCEEEEEEE	28.34	-
62	Phosphorylation	PLLIGKFTLLKSLSL CCEECCEEEEEEECC	34.37	-
85	Ubiquitination	PDEICNLKKLETLSL CHHHHCCCCCCEEEC	41.12	-
86	Ubiquitination	DEICNLKKLETLSLN HHHHCCCCCCEEECC	55.51	-
140	Ubiquitination	LDVMDLSKNQIRSIP CCHHCCCHHHHHCCC	61.23	21890473
226	Ubiquitination	RELEGYDKYMERFTA HHHCCHHHHHHHHHH	37.70	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LRC57_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LRC57_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LRC57_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CE030_HUMAN	C5orf30	physical	28514442
LRC40_HUMAN	LRRC40	physical	28514442
SGT1_HUMAN	SUGT1	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.