LRC51_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LRC51_HUMAN
• UniProt AC: Q96E66
• Protein Name: Leucine-rich repeat-containing protein 51
• Gene Name: LRTOMT
• Organism: Homo sapiens (Human).
• Sequence Length: 192
• Subcellular Localization: Cytoplasm.
• Protein Sequence: MNKRDYMNTSVQEPPLDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYRQYVLCTLSRITTFDFSGVTKADRTTAEVWKRMNIKPKKAWTKQNTL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7 (in isoform 6)	Phosphorylation	-	5.30	24043423
9 (in isoform 6)	Phosphorylation	-	17.47	24043423
18 (in isoform 6)	Phosphorylation	-	19.86	24043423
22	Phosphorylation	PLDYSFRSIHVIQDL CCCCCHHHHHHHHHH	18.29	25693802
22 (in isoform 2)	Phosphorylation	-	18.29	25693802
22 (in isoform 3)	Phosphorylation	-	18.29	25693802
22 (in isoform 4)	Phosphorylation	-	18.29	25693802
22 (in isoform 5)	Phosphorylation	-	18.29	25693802
35 (in isoform 6)	Phosphorylation	-	44.71	-
36	Phosphorylation	LVNEEPRTGLRPLKR HHCCCCCCCCCCCCC	51.81	-
36 (in isoform 2)	Phosphorylation	-	51.81	-
36 (in isoform 3)	Phosphorylation	-	51.81	-
36 (in isoform 4)	Phosphorylation	-	51.81	-
36 (in isoform 5)	Phosphorylation	-	51.81	-
53 (in isoform 3)	Phosphorylation	-	19.10	-
53 (in isoform 5)	Phosphorylation	-	19.10	-
53 (in isoform 4)	Phosphorylation	-	19.10	-
53	Phosphorylation	SGKSLTQSLWLNNNV CCCCHHHHHHHCCCH	19.10	-
53 (in isoform 2)	Phosphorylation	-	19.10	-
139 (in isoform 6)	Phosphorylation	-	13.52	-
140 (in isoform 6)	Phosphorylation	-	65.35	-
157	Phosphorylation	LCTLSRITTFDFSGV EEEECCCEEECCCCC	21.94	-
158	Phosphorylation	CTLSRITTFDFSGVT EEECCCEEECCCCCC	20.88	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LRC51_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LRC51_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LRC51_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
JOS2_HUMAN	JOSD2	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.