LRC10_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LRC10_HUMAN
• UniProt AC: Q5BKY1
• Protein Name: Leucine-rich repeat-containing protein 10
• Gene Name: LRRC10
• Organism: Homo sapiens (Human).
• Sequence Length: 277
• Subcellular Localization: Nucleus.
• Protein Description: May play important roles in cardiac development and/or cardiac function..
• Protein Sequence: MGNTIRALVAFIPADRCQNYVVRDLREMPLDKMVDLSGSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILYLGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGSNALRLLPGQLRRLQELRTIWLSGNRLTDFPTVLLHMPFLEVIDVDWNSIRYFPSLAHLSSLKLVIYDHNPCRNAPKVAKGVRRVGRWAEETPEPDPRKARRYALVREESQELQAPVPLLPPTNS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MGNTIRALVAF ----CCCCHHHHHEE	13.20	24719451
20	Phosphorylation	PADRCQNYVVRDLRE CHHHHCCHHHCHHHH	3.72	24719451
144	Phosphorylation	PDVVCELSLLKTLHA CHHHHHHHHHHHHHC	14.90	24719451
212	Phosphorylation	FPSLAHLSSLKLVIY CCCHHHHHCCEEEEE	24.61	24719451
255	Phosphorylation	DPRKARRYALVREES CHHHHHHHHHHHHHH	9.95	-
262	Phosphorylation	YALVREESQELQAPV HHHHHHHHHHCCCCC	24.97	26699800
275	Phosphorylation	PVPLLPPTNS----- CCCCCCCCCC-----	46.27	26699800
277	Phosphorylation	PLLPPTNS------- CCCCCCCC-------	44.04	26699800

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LRC10_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LRC10_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LRC10_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ENOF1_HUMAN	ENOSF1	physical	28514442
TCPW_HUMAN	CCT6B	physical	28514442
SGT1_HUMAN	SUGT1	physical	28514442
RHG08_HUMAN	ARHGAP8	physical	28514442
TCPB_HUMAN	CCT2	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.