LIN2_CAEEL - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LIN2_CAEEL
• UniProt AC: P54936
• Protein Name: Protein lin-2
• Gene Name: lin-2
• Organism: Caenorhabditis elegans.
• Sequence Length: 961
• Protein Description: May play a structural role in the induction of the vulva. May be required for the localization of signal transduction molecules (such as let-23 receptor) to either the basal membrane domain or the cell junctions..
• Protein Sequence: MRELDPDESNLLLDEQLSIRDVIEQGPFSNVYRILHGPSNRKFLLRSINLNLFRQHTGLGFEEIDEEIRICQNLQHPYICRLEKTINSVHYRHIIFENMEGNDICFEIVQRASNGFVFSEYVVSHYTRQLLDALDYCHTRKIVHRDVRPHNLVLASKDTSAPLKLCGFGVAKDLSEIGGSMACGRVGVPQFMAPEIVRKDRVSCSSDIWSSGVVLFLLLAGRLPFSGSTSDIYERIMQTDVDVDGYMPNISESARNLVRRMLNADPSKRISAKEALNHEWIRDKEHMASRKHMNDVIDQMRRYNESRKLKSNVLSAVNSGRFDETTPRQDTPQTAFVDGSSPGGDCCHRGESSSNDAAEPPADKDLSGAYKVLGSLDAINSLLDPNSYKPGSTTFQKIHDDGSVRNLLRLYDKIKALPCEPVVTEVDTSTLRKETLNQIDGLLGPSPEALELRQLLNSPHLASCVQALDVVVCEIRDPKNEASGSGDKEGNCVSSDPAPAYLNGGVLPLGAQRAGTSFEHFNQSAVHTSYDEEEEELYDCMSRLRLVQFQKDTQEPMGITLKVNEDGRCFVARIMHGGMIHRQATLHVGDEIREINGMSVANRSVESLQEMLRDARGQVTFKIIPSYRSAPPACEIFVRAQFDYEPSQDDLIPCPQAGIPFKTGDILQVISKDDHNWWQARFVSSFPSIGNSSNAQRSNQQQVAGLIPSPELQEWRTACLAMERSKNTCNTHCMWFNKKKKYYTTKYLQKHSALFDQLDLVTYEEVMRLSQYRRKTLVLLGAHGVGRRHIKNTLIHRHPNRFAYPIPHTTRPPRKDEVDGKHYYFVTNEQMMADIQNNEYLEYGTHEESMYGTKLETIRNIHKSGKIAILDVEPQALKVLRTAEYSPFVVFIAAPNLQGMQDPDGSLEKLLNESDVLRQAFGHLFDFIITNSDIDDTIAQLERLVEKLPAYPQWLPVTWVY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
458	Phosphorylation	ELRQLLNSPHLASCV HHHHHHCCHHHHHHH	17.42	30078680

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LIN2_CAEEL !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LIN2_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LIN2_CAEEL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TYR1_CAEEL	tyr-1	physical	14704431
SUMV1_CAEEL	sumv-1	physical	14704431
UNC87_CAEEL	unc-87	physical	14704431
HIF1_CAEEL	hif-1	physical	14704431
YMV2_CAEEL	K04H4.2	physical	14704431
G3P3_CAEEL	gpd-3	physical	14704431
MEP1_CAEEL	mep-1	physical	14704431
COQ5_CAEEL	coq-5	physical	14704431

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.