KRT82_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: KRT82_HUMAN
• UniProt AC: Q9NSB4
• Protein Name: Keratin, type II cuticular Hb2
• Gene Name: KRT82
• Organism: Homo sapiens (Human).
• Sequence Length: 513
• Protein Sequence: MSYHSFQPGSRCGSQSFSSYSAVMPRMVTHYAVSKGPCRPGGGRGLRALGCLGSRSLCNVGFGRPRVASRCGGTLPGFGYRLGATCGPSACITPVTINESLLVPLALEIDPTVQRVKRDEKEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQRCCQTNIEPIFEGYISALRRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADLETNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLCEGIGPVNISVSSSKGAFLYEPCGVSTPVLSTGVLRSNGGCSIVGTGELYVPCEPQGLLSCGSGRKSSMTLGAGGSSPSHKH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
137	"N6,N6-dimethyllysine"	RFASFINKVRFLEQK HHHHHHHHHHHHHHH	29.94	-
137	Methylation	RFASFINKVRFLEQK HHHHHHHHHHHHHHH	29.94	-
174	Phosphorylation	PIFEGYISALRRQLD HHHHHHHHHHHHHHC	16.87	22210691
207	"N6,N6-dimethyllysine"	ALEGYKKKYEEELSL HHHHHHHHHHHHHCC	54.46	-
207	Methylation	ALEGYKKKYEEELSL HHHHHHHHHHHHHCC	54.46	-
208	Phosphorylation	LEGYKKKYEEELSLR HHHHHHHHHHHHCCC	37.14	19764811
213	Phosphorylation	KKYEEELSLRPCVEN HHHHHHHCCCCCCCC	26.13	24719451
231	Phosphorylation	ALKKDVDTAFLMKAD EEECCCCHHHHHHCC	21.11	-
354	"N6,N6-dimethyllysine"	QQETENVKAQRCKLE HHHHHCHHHHHHHHH	50.84	-
354	Methylation	QQETENVKAQRCKLE HHHHHCHHHHHHHHH	50.84	-
409	Phosphorylation	EYQEVMNSKLGLDIE HHHHHHHHCCCCCEE	15.91	27251275
499	Phosphorylation	CGSGRKSSMTLGAGG CCCCCCCCCCCCCCC	20.87	29853039
501	Phosphorylation	SGRKSSMTLGAGGSS CCCCCCCCCCCCCCC	24.80	30576142
508	Phosphorylation	TLGAGGSSPSHKH-- CCCCCCCCCCCCC--	33.43	30576142
510	Phosphorylation	GAGGSSPSHKH---- CCCCCCCCCCC----	47.30	30576142

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of KRT82_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of KRT82_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of KRT82_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
K1C16_HUMAN	KRT16	physical	26344197

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.