KCTD4_HUMAN - dbPTM
KCTD4_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID KCTD4_HUMAN
UniProt AC Q8WVF5
Protein Name BTB/POZ domain-containing protein KCTD4
Gene Name KCTD4
Organism Homo sapiens (Human).
Sequence Length 259
Subcellular Localization
Protein Description
Protein Sequence MERKINRREKEKEYEGKHNSLEDTDQGKNCKSTLMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLLFRHVLNFLRNGELLLPEGFRENQLLAQEAEFFQLKGLAEEVKSRWEKEQLTPRETTFLEITDNHDRSQGLRIFCNAPDFISKIKSRIVLVSKSRLDGFPEEFSISSNIIQFKYFIKSENGTRLVLKEDNTFVCTLETLKFEAIMMALKCGFRLLTSLDCSKGSIVHSDALHFIK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
14PhosphorylationRREKEKEYEGKHNSL
HHHHHHHHCCCCCCC
40.84-
20PhosphorylationEYEGKHNSLEDTDQG
HHCCCCCCCCCCCCC
32.6229514088
24PhosphorylationKHNSLEDTDQGKNCK
CCCCCCCCCCCCCCC
22.3522210691
44PhosphorylationLNVGGYLYITQKQTL
EEECCEEEEEECEEC
8.08-
52PhosphorylationITQKQTLTKYPDTFL
EEECEECCCCCCCCC
31.7427251275
57PhosphorylationTLTKYPDTFLEGIVN
ECCCCCCCCCHHHCC
26.1422210691
128PhosphorylationGLAEEVKSRWEKEQL
HHHHHHHHHHHHHHC
48.0427134283
176PhosphorylationKSRIVLVSKSRLDGF
HHCEEEEEHHHCCCC
22.2829514088
178PhosphorylationRIVLVSKSRLDGFPE
CEEEEEHHHCCCCCC
30.4829514088
219PhosphorylationEDNTFVCTLETLKFE
CCCEEEEEEECHHHH
23.48-
222PhosphorylationTFVCTLETLKFEAIM
EEEEEEECHHHHHHH
38.06-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of KCTD4_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of KCTD4_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of KCTD4_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
KCTD4_HUMANKCTD4physical
16189514
KCTD4_HUMANKCTD4physical
25416956

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of KCTD4_HUMAN

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Related Literatures of Post-Translational Modification

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